目的:探讨心房颤动(AF)合并认知障碍(CI)的危险因素,并分析患者心功能参数与CI程度的关系。
方法:选择120例房颤患者,蒙特利尔认知评估(MoCA)用于区分有CI和无CI的AF患者。单因素分析和多因素Logistic回归分析用于评估社会人口统计学数据的影响。疾病相关数据,和CI房颤危险因素的临床数据。采用Pearson方法分析房颤患者心功能参数与认知功能评分的相关性。
结果:有89例CI患者和31例CI患者,CI患者的MoCA评分低于CI患者。年龄,职业状况,教育水平,综合吸烟史,饮酒史,心力衰竭,以及收缩压,舒张压,总胆固醇,甘油三酯,C反应蛋白,游离甲状腺素,游离三碘甲状腺原氨酸,和D-二聚体是CI患者的危险因素。左心房直径,左心室舒张末期直径,左心室收缩末期直径,CI患者的左心房最大容积高于CI患者,左心室射血分数和舒张早期峰值/舒张晚期峰值二尖瓣速度比更低。
结论:患者的心功能参数与注意密切相关,定位,记忆,视觉空间,和执行能力。心功能参数与认知功能密切相关。
To explore the risk factors of Atrial Fibrillation (AF) with Cognitive Impairment (CI) and to analyze the relationship between cardiac function parameters and the degree of CI in patients.
120 AF patients were selected, and Montreal Cognitive Assessment (MoCA) was used to distinguish between AF patients with and without CI. Univariate analysis and multivariate Logistic regression analysis were used to evaluate the impact of sociodemographic data, disease-related data, and clinical data on risk factors for AF with CI. Pearson\'s method was used to analyze the correlation between cardiac function parameters and cognitive function scores in AF patients.
There were 89 patients with CI and 31 patients without CI, and the MoCA scores of patients with CI were lower than those in patients without CI. Age, occupational status, educational level, combined smoking history, drinking history, and heart failure, as well as systolic blood pressure, diastolic blood pressure, total cholesterol, triglyceride, C-reactive protein, free thyroxine, free triiodothyronine, and D-dimer were risk factors for the patient with CI. Left atrial diameter, left ventricular end-diastolic diameter, left ventricular end-systolic diameter, and left atrial maximum volume in patients with CI were higher than those in patients without CI, and left ventricular ejection fraction and peak early diastolic velocity/peak late-diastolic mitral velocity ratio were lower.
The cardiac function parameters of patients are closely related to attention, orientation, memory, visuospatial, and executive ability. Cardiac function parameters were closely related to cognitive functions.