杜仲(EU)是中国原产于冰河时代的珍贵树种。该物种具有重要的经济价值和综合发展潜力,特别是在医疗应用中。欧盟的药用部分是其树皮(杜仲皮层)和叶(杜仲叶),自公元前一世纪以来,它们已被连续用作中药治疗疾病。在过去的20年里,随着天然多糖对药理学的兴趣越来越大,生物医学,化妆品和食品应用,越来越多的学者也开始研究欧盟多糖。已经发现欧盟多糖在体内和体外都具有多种生物学功能,包括免疫调节,抗氧化剂,抗炎,反互补,抗疲劳,和肝保护活动。这篇综述旨在总结提取方面的这些最新进展,净化,结构特征,欧盟树皮和叶多糖的药理活性及其在不同领域的应用。发现杜仲叶多糖和杜仲叶多糖均适合药用。在免疫调节和抗氧化活性方面,杜仲叶有可能替代杜仲叶。本研究对提高欧盟多糖的综合利用水平,进一步促进欧盟多糖的应用具有一定的参考价值。
Eucommia ulmoides (EU) is a precious tree species native to
China originating during the ice age. This species has important economic value and comprehensive development potential, particularly in medicinal
applications. The medicinal parts of EU are its bark (Eucommiae cortex) and leaves (Eucommiae folium) which have been successively used as a traditional Chinese medicine to treat diseases since the first century BC. During the last 2 decades, as natural polysaccharides have become of increasing interest in pharmacology, biomedicine, cosmetic and food
applications, more and more scholars have begun to study polysaccharides derived from EU as well. EU polysaccharides have been found to have a variety of biological functions both in vivo and in vitro, including immunomodulatory, antioxidant, anti-inflammatory, anticomplementary, antifatigue, and hepatoprotective activities. This review aims to summarize these recent advances in extraction, purification, structural characteristics, pharmacological activities and
applications in different fields of EU bark and leaf polysaccharides. It was found that both Eucommiae folium polysaccharides and Eucommiae cortex polysaccharides were suitable for medicinal use. Eucommiae folium may potentially be used to substitute for Eucommiae cortex in terms of immunomodulation and antioxidant activities. This study serves as a valuable reference for improving the comprehensive utilization of EU polysaccharides and further promoting the application of EU polysaccharides.