Anatomic Variation

解剖变异
  • 文章类型: Journal Article
    目的:回顾性分析血液病患者DSA血管造影过程中血管的异常解剖改变,对短期(≤6个月)反复咯血的影响因素进行统计学分析,评估入院诊断与术中诊断的一致性。
    方法:回顾性分析2022年1月至2022年12月在我院行选择性支气管动脉栓塞治疗咯血患者的术中血管造影资料。根据是否复发咯血分为观察组和对照组。采用Logistic回归模型和森林图分析影响复发率的因素。
    结果:本研究共纳入104例患者(12例结核病,35例感染,肺癌4例,支气管扩张8例,22例动静脉瘘,16例动脉瘤,和7例肺动脉高压)。术前和术中诊断符合率为73.1%。肺动静脉瘘和动脉瘤是误诊的主要疾病类型。短期复发率为16.3%,主要归因于与栓塞相关的负责血管的重新开放,血管造影渗漏,和特定类型血管的渗漏栓塞。仅有动静脉瘘和动脉瘤的患者复发率占总复发率的47%。右支气管动脉,右胸廓内动脉,右甲状腺颈干,年龄是影响咯血复发的独立因素(p<0.05)。
    结论:咯血病例中血管造影渗漏和栓塞渗漏的主要原因是对负责血管的解剖变异缺乏了解。仔细检查船只的特定类型和位置是减少二次作业的主要方法。
    OBJECTIVE: The abnormal anatomical alterations of blood vessels during DSA angiography in patients with hematological disorders were retrospectively examined, and the influencing factors of short-term (≤ 6 months) recurrent hemoptysis were statistically analyzed, and the consistency between admission diagnosis and intraoperative diagnosis was evaluated.
    METHODS: The intraoperative angiography data of patients who underwent selective bronchial artery embolization for hemoptysis in our hospital from January 2022 to December 2022 were reviewed. They were divided into the observation group and the control group based on whether there was recurrent hemoptysis. The Logistic regression model and forest map were employed to analyze the factors influencing the recurrence rate.
    RESULTS: A total of 104 patients were encompassed in this study (12 cases of tuberculosis, 35 cases of infection, 4 cases of lung cancer, 8 cases of bronchiectasis, 22 cases of arteriovenous fistula, 16 cases of aneurysm, and 7 cases of pulmonary hypertension). The coincidence rate of preoperative and intraoperative diagnoses was 73.1%. Pulmonary arteriovenous fistula and aneurysm were the predominant types of diseases that were misdiagnosed. The short-term recurrence rate was 16.3%, mainly attributed to the reopening of responsible vessels related to embolization, angiography leakage, and leaky embolization of specific types of vessels. The recurrence rate of only patients with arteriovenous fistula and aneurysm accounted for 47% of the total recurrence rate. The right bronchial artery, right internal thoracic artery, right thyroid neck trunk, and age were the independent factors influencing the recurrence of hemoptysis (p < 0.05).
    CONCLUSIONS: The main reason for angiographic leakage and embolization leakage in cases of hemoptysis is the lack of understanding of the anatomic variations of the vessels responsible. Careful examination of the specific types and locations of the vessels is the principal approach to reducing secondary operations.
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  • 文章类型: Journal Article
    目的:目前对二尖瓣环分离(MAD)作为一种可能与室性心律失常相关的解剖学异常的认识引发了关于其患病率和临床意义的争议。本研究旨在使用增强心脏CT来调查无明显结构异常的个体中MAD的患病率和程度。在探索潜在因素的同时,比如年龄,这可能与MAD有关。
    方法:回顾性纳入742名受试者的心脏CT收缩数据集。通过围绕二尖瓣环的中心轴旋转正交多平面重建图像来确定MAD。最大分离距离(DMAD)和所涉及的段(SI,对左心室壁的0至5个基底段)进行定量以评估分离程度。
    结果:总计,449(60.5%)患有MAD。MAD患者年龄明显较大(51.3±19.9岁与29.6±20.3年,P<0.001)。年龄是MAD的独立相关因素(OR=1.059;95CI:1.033,1.085;P<0.001)。然后将MAD受试者分为4个亚组(G1:≤20岁,G2:21-40年,G3:41-60岁,G4:≥61岁)。每个年龄亚组的DMAD和SI为1.9±0.2mm,2.0±1.2(G1,n=36),2.7±0.8mm,2.9±1.3(G2,n=51),3.0±0.8mm,3.0±1.3(G3,n=183),和3.0±1.0毫米,3.7±1.1(G4,n=179)。年龄是DMAD的独立相关因素(R2=0.132;β=0.014;95CI:0.004,0.024;P=0.007)和SI(OR=1.030;95CI:1.005,1.055;P=0.016)。
    结论:MAD是心脏CT的常见发现。其患病率和程度随年龄增长而增加。
    OBJECTIVE: The current recognition of mitral annular disjunction (MAD) as an anatomical abnormality potentially associated with ventricular arrhythmias has sparked controversy regarding its prevalence and clinical implications. This study aimed to investigate the prevalence and extent of MAD in individuals with no significant structural abnormalities involving the left heart using enhanced cardiac CT, while also exploring potential factors, such as age, that may be associated with MAD.
    METHODS: Systolic datasets of cardiac CT from 742 subjects were retrospectively included. MAD was determined by rotating orthogonal multiplanar reconstruction images around the central axis of the mitral annulus. The maximal distance of disjunction (DMAD) and segments involved (SI, 0 to 5 basal segments at left ventricular wall) was quantified to evaluate the extent of separation.
    RESULTS: In total, 449 (60.5%) had MAD. Subjects with MAD were significantly older (51.3 ± 19.9 years vs. 29.6 ± 20.3 years, P < 0.001). Age was found to be an independent relevant factor for MAD (OR = 1.059; 95%CI: 1.033, 1.085; P < 0.001). Subjects with MAD were then divided into 4 subgroups (G1: ≤20 years, G2: 21-40 years, G3: 41-60 years, G4: ≥61 years). DMAD and SI of each age subgroup were 1.9 ± 0.2 mm, 2.0 ± 1.2 (G1, n = 36), 2.7 ± 0.8 mm, 2.9 ± 1.3 (G2, n = 51), 3.0 ± 0.8 mm, 3.0 ± 1.3 (G3, n = 183), and 3.0 ± 1.0 mm, 3.7 ± 1.1 (G4, n = 179). Age was an independent relevant factor associated with DMAD (R2 = 0.132; β = 0.014; 95%CI: 0.004, 0.024; P = 0.007) and SI (OR = 1.030; 95%CI: 1.005, 1.055; P = 0.016).
    CONCLUSIONS: MAD is a common finding on cardiac CT. Its prevalence and extent increase with age.
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  • 文章类型: Journal Article
    目的:本研究的目的是使用三维可视化和评估(3DVE)开发一种新的,更全面的门静脉(PV)变异分类系统,并讨论变异的患病率和临床意义。
    方法:通过使用2013年至2022年之间获取的CT图像的三维可视化来跟踪和分析PVs的解剖结构。评估了来自200名成年人的扫描,总共178名患者(N=178)被纳入研究。新的分类系统,命名为BLB分类,是根据每个变异解剖结构中不存在的PV分支的水平开发的。
    结果:使用BLB分类系统,PV分为13种亚型。只有82.6-84.8%的178例患者的门静脉被描绘在Atri's,程或柯维的分类,与BLB分类确定的100%相比。BLB分类已根据先前研究的外部数据集进行了验证,97.0-98.9%的患者按BLB系统分类。
    结论:基于3DVE的变异PV解剖比以前的报告更常见。BLB分类涵盖了几乎所有的门静脉变异,可用于规划肝脏手术。
    OBJECTIVE: The purpose of this study was to develop a new and more comprehensive classification system for portal vein (PV) variations using three-dimensional visualization and evaluation (3DVE) and to discuss the prevalence rates and clinical implications of the variants.
    METHODS: The anatomies of PVs were tracked and analyzed by using three-dimensional visualization of CT images acquired between 2013 and 2022. Scans from 200 adults were evaluated and a total of 178 patients (N = 178) were included in the study. The new classification system, named BLB classification, was developed based on the level of the absent PV branch in each variant anatomy.
    RESULTS: Using the BLB classification system, PVs were divided into thirteen subtypes. Only 82.6-84.8% of the portal veins of the 178 patients were depicted in Atri\'s, Cheng\'s or Covey\'s classification, compared with 100% identified by the BLB classification. The BLB classification was validated against external data sets from previous studies, with 97.0-98.9% of patients classified by the BLB system.
    CONCLUSIONS: Variant PV anatomies are more commonly seen based on 3DVE than in previous reports. The BLB classification covers almost all portal vein variants and may be used for planning liver surgery.
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  • 文章类型: Case Reports
    背景:这项研究旨在描述双肠系膜上静脉(SMV)的发现,一种罕见的解剖学变异,多探测器计算机断层扫描(MDCT)和磁共振成像(MRI)图像。
    方法:我们描述了一个34岁男性的案例,由于肝硬化而接受了上腹部MDC和MRI检查。上腹部的MDCT和MRI血管造影图像显示肠系膜上静脉(SMV)的解剖变异,双SMV。
    结论:双SMV是一种先天性异常,没有潜在的临床表现。医生需要在腹部手术期间意识到这种解剖变化,以避免医源性损伤。
    BACKGROUND: This study aimed to describe the findings of double superior mesenteric veins (SMVs), a rare anatomical variation, on multidetector computer tomography (MDCT) and magnetic resonance imaging (MRI) images.
    METHODS: We describe the case of a 34-year-old male, who underwent both MDC and MRI examinations of the upper abdomen because of liver cirrhosis. MDCT and MRI angiography images of the upper abdomen revealed an anatomic variation of the superior mesenteric vein (SMV), the double SMVs.
    CONCLUSIONS: The double SMVs are a congenital abnormality without potential clinical manifestation. Physicians need to be aware of this anatomical variation during abdominal surgery to avoid iatrogenic injury.
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  • 文章类型: Journal Article
    背景:由于臂丛神经的复杂解剖结构及其变异倾向,臂丛神经损伤被认为是最严峻的临床挑战之一,这使得安全的临床干预复杂化。本研究旨在确定臂丛神经变异的患病率和特征类型,并阐明其临床意义。
    方法:我们对60具福尔马林固定的上臂尸体进行了细致的解剖,腋下和下颈部来揭示和评估根部,树干,师,绳索,臂丛的分支.一组解剖的医学生注意到了分支的模式,并得到了高级解剖学家的证实。使用数码相机记录并拍摄发现的变化以进行进一步分析。
    结果:在60具尸体中的40具发现了臂丛神经的变异,患病率为66.7%。这些变异被分类为根部异常(2.1%),树干异常(8.5%),分区异常(2.1%),和脐带异常(4.3%)。值得注意的是,在39具尸体中观察到交通分支异常(83.0%):14具双侧异常,14左侧有异常,11在右边这些通信分支形成了根和其他段之间的连接,包括树干,绳索,和终末神经,涉及中位数,肌肉皮肤,尺神经.
    结论:臂丛神经变异的频率和多样性,特别是在通信分支机构中,在尸体中很重要。必须在诊断过程中仔细考虑这些变化,治疗计划,在锁骨上臂丛神经阻滞和神经转移等手术之前,降低医源性并发症的风险。
    BACKGROUND: Brachial plexus injury is recognized as one of the most severe clinical challenges due to the complex anatomical configuration of the brachial plexus and its propensity for variation, which complicates safe clinical interventions. This study aimed to ascertain the prevalence and characterize the types of brachial plexus variations, and to elucidate their clinical implications.
    METHODS: We conducted meticulous dissections of 60 formalin-fixed cadavers\' upper arm, axilla and lower neck to reveal and assess the roots, trunks, divisions, cords, and branches of the brachial plexus. The pattern of branching was noted by groups of dissecting medical students and confirmed by the senior anatomists. The variations discovered were record and photographed using a digital camera for further analysis.
    RESULTS: Variations in the brachial plexus were identified in 40 of the 60 cadavers, yielding a prevalence rate of 66.7%. These variations were classified into root anomalies (2.1%), trunk anomalies (8.5%), division anomalies (2.1%), and cord anomalies (4.3%). Notably, anomalies in communicating branches were observed in 39 cadavers (83.0%): 14 with bilateral anomalies, 14 with anomalies on the left side, and 11 on the right side. These communicating branches formed connections between the roots and other segments, including trunks, cords, and terminal nerves, and involved the median, musculocutaneous, and ulnar nerves.
    CONCLUSIONS: The frequency and diversity of brachial plexus variations, particularly in communicating branches, are significant in cadavers. It is imperative that these variations are carefully considered during the diagnostic process, treatment planning, and prior to procedures such as supraclavicular brachial plexus blocks and nerve transfers, to mitigate the risk of iatrogenic complications.
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  • 文章类型: Journal Article
    目的:本研究的目的是介绍足舟骨骨的分类及诊断和治疗的解剖学基础。
    方法:对351张舟骨的计算机断层扫描(CT)图像进行分析和分类。每种类型的舟骨的解剖形态由三名独立的研究人员测量。随后分析和记录测量结果。
    结果:舟骨分为三种类型:I形(37.04%),II型(54.41%),和III形(8.55%)。左侧和右侧没有任何明显的区别,除了AB,BC,和浴abc(P<0.05);除浴abc(p>0.05)外,所有数据男女间差异均有统计学意义。
    结论:本研究中舟骨的分类可能有助于制定舟骨骨折的治疗决策。
    方法:4.
    OBJECTIVE: The purpose of this study was to present the classification of navicular bones and the anatomical basis for the diagnosis and treatment of navicular fractures of the foot.
    METHODS: 351 computed tomographic (CT) images of the navicular bone were analyzed and classified. The navicular bone\'s anatomical morphology was measured by three independent researchers in each type. Analysis and recording of the measurement results followed.
    RESULTS: Navicular bones were assorted into three types: I shape(37.04%), II shape(54.41%), and III shape(8.55%). The left and right sides did not differ in any appreciable ways, except ab, bc, and ∠abc (P < 0.05); And all data were statistically different between men and women except for ∠abc (p > 0.05).
    CONCLUSIONS: The classification of the navicular bone in this study may be helpful in making the treatment decision for navicular fracture.
    METHODS: 4.
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  • 文章类型: Journal Article
    目的:本研究使用锥形束计算机断层扫描(CBCT)评估直径,患病率,空间位置,和窦性管副管(AC)的危险因素。
    方法:对发病率进行综合评估,直径,三维(3D)空间位置,在1003张CBCT图像上进行AC的行进方向。CBCT数据用于重建上颌骨的3D模型以确定牙槽骨体积。对所得数据进行进一步分析和处理。
    结果:在50.1%的图像中存在AC。男性患者的ACs发生率高于女性患者(P<0.01),并且与上颌牙槽骨体积呈正相关(P<0.001,OR1.532)。年龄或鼻腭管直径与AC的发生无显著相关性(P>0.05)。在502例AC患者中,空调出现在左侧,右侧,和双边分别在189、98和215中。每个个体观察到的AC的最大数目为8。平均AC直径为0.89±0.26mm(最小,0.5mm;最大值,2.02mm)。
    结论:由于AC的患病率及其轨迹在个体之间显示出相当大的差异,在制定涉及上颌前区的手术计划时,外科医生必须考虑存在AC的可能性。
    OBJECTIVE: Cone-beam computed tomography (CBCT) was used in this study for evaluating the diameter, prevalence, spatial location, and risk factors of the accessory canal (AC) of the canalis sinuosus.
    METHODS: A comprehensive assessment of the incidence rate, diameter, three-dimensional (3D) spatial location, and direction of travel of AC was performed on 1003 CBCT images. The CBCT data were used to reconstruct a 3D model of the maxilla to determine the alveolar bone volume. The obtained data were further analyzed and processed.
    RESULTS: AC was present in 50.1% of images. Male patients more frequently had ACs than female patients did (P < 0.01) and was positively correlated with the maxillary alveolar bone volume (P < 0.001, OR 1.532). Age or nasopalatine canal diameter were not significantly associated with the occurrence of AC (P > 0.05). Among the 502 patients with AC, AC was present on the left side, right side, and bilaterally in 189, 98, and 215, respectively. The maximum number of ACs observed per individual was eight. The average AC diameter was 0.89 ± 0.26 mm (minimum, 0.5 mm; maximum, 2.02 mm).
    CONCLUSIONS: As the prevalence of AC and its trajectory display considerable variation among individuals, surgeons must consider the possibility of the presence of AC when devising surgical plans involving the anterior maxillary region.
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  • 文章类型: Journal Article
    背景:了解眶下动脉(IOA)的解剖结构对于恢复中面前内侧至关重要;但是,缺乏充分描述IOA分支解剖结构的研究,它们与眼动脉分支的联系尚不清楚。
    目的:本研究旨在使用三维(3D)技术阐明IOA在下眼睑内展开的解剖学特征,从而为临床外科手术提供解剖学基础。
    方法:对132具尸体头侧造影剂注射后的计算机断层扫描进行了分析,利用Mimics软件进行重建。这项研究的重点是检查IOA的吻合,它的主要分支,和从眼动脉发出的分支。
    结果:观察到I型IOA的患病率为38.6%(51/132),而II型IOA在61.4%(81/132)的病例中发现。观察到IOA与角动脉直接吻合的发生率为7.6%(10/132)。在57.6%(76/132)的病例中发现了眼睑分支(PIOA)的存在。在下眼睑,发现了四种不同的IOA分布模式:I型PIOA的可能性为5.3%,而对于类型IIA,IIB,还有IICPIOA,概率为8.3%,32.6%,和11.4%,分别。IOA轨道分支的发生率为41.7%(55/132)。
    结论:3D技术可以以高分辨率绘制IOA变异,并确定IOA分支在下眼睑血管囊泡中的展开模式,作为临床实践的指导。
    方法:本期刊要求作者为每篇文章分配一定程度的证据。对于这些循证医学评级的完整描述,请参阅目录或在线作者说明www。springer.com/00266.
    BACKGROUND: Knowledge of the anatomy of the infraorbital artery (IOA) is crucial for the rejuvenation of the anterior medial aspect of the midface; however, studies adequately describing the anatomy of the IOA branches are lacking, and their connection with the ophthalmic artery branches remains unclear.
    OBJECTIVE: This study aims to elucidate the anatomical characteristics of the IOA in its deployment within the lower eyelid using three-dimensional (3D) technology, thereby offering an anatomical foundation for clinical surgical procedures.
    METHODS: An analysis was conducted on computed tomography scans of 132 cadaveric head sides post-contrast injection, utilizing the Mimics software for reconstruction. The study focused on examining the anastomosis of the IOA, its principal branches, and the branches emanating from the ophthalmic artery.
    RESULTS: The prevalence of type I IOA was observed at 38.6% (51/132), while Type II IOA was found in 61.4% (81/132) of cases. A 7.6% incidence (10/132) of IOA directly anastomosing with the angular artery was noted. The presence of palpebral branches (PIOA) was identified in 57.6% (76/132) of instances. In the lower eyelid, four distinct distribution patterns of IOA were discerned: The likelihood of Type I PIOA was 5.3%, whereas for Types IIA, IIB, and IIC PIOA, the probabilities were 8.3%, 32.6%, and 11.4%, respectively. The occurrence of the orbital branch of IOA was recorded at 41.7% (55/132).
    CONCLUSIONS: 3D technology can map IOA variants and identify the deployment patterns of IOA branches in the lower eyelid vascular vesicles at high resolution as a guide in clinical practice.
    METHODS: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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  • 文章类型: Journal Article
    关于解剖变异与后鼻孔息肉(ACP)发展之间的联系的研究很少,ACP的病因尚不清楚。本研究旨在探讨解剖变异之间的关系,上颌窦容积,鼻道相关参数,以及ACP的发生。
    在2010年2月至2020年2月期间,在山东省耳鼻喉科医院接受单方ACP治疗的回顾性横断面研究中,纳入了127例患者。评价指标包括解剖变异,上颌窦容积,45名儿童和82名成人的鼻道相关参数,通过3DSlicer软件进行了两次评估。使用Kolmogorov-Smirnov检验评估参数,其次是配对t检验和卡方检验进行多重比较。
    两侧的副上颌口(AMO)和上颌窦保留囊肿存在显着差异(均P<0.001)。上颌窦体积和性别在成人ACP侧(P=0.026)和非经前肛门息肉(非ACP)侧(P=0.032)具有统计学意义。患侧上颌窦体积明显大于健康侧(P<0.001)。儿童从上颌窦口到ACP侧中鼻甲最外侧边缘平面的长度大于非ACP侧(P=0.044)。从上颌窦口到ACP侧中鼻甲最外侧边缘平面的雄性长度明显大于健康侧(P<0.001)。非ACP侧上颌窦口至中鼻甲最外侧缘平面的长度(P=0.014)和下鼻甲至鼻中隔的长度(P=0.013)高于成人患侧。健康侧从下鼻甲到鼻中隔的男性长度高于患侧(P<0.001)。男性在非ACP侧从上颌窦侧壁到鼻中隔的最大长度(P=0.024)和从下鼻甲到鼻中隔的长度(P=0.003)比女性长。男性从上颌窦外侧壁到ACP侧鼻中隔的最大长度比女性大(P=0.011)。
    在我们的研究中,AMO的发生,上颌窦扩大的大小,窦道复合体和共同鼻道周围相关通道的狭窄被认为可能与ACP的形成有关。此外,涉及窦道复合体并可能导致上颌窦压力和鼻通气变化的解剖变异是ACP形成的重要因素。
    UNASSIGNED: There is little investigation into the connection between anatomic variations and the development of antrochoanal polyp (ACP), and the etiology of ACP remains unclear. The study aims to explore the relationship among anatomic variations, maxillary sinus volume, nasal meatus-related parameters, and the occurrence of ACP.
    UNASSIGNED: There were 127 patients included in this retrospective cross-sectional study with unilateral ACPs hospitalized at Shandong Provincial ENT Hospital between February 2010 and February 2020. Evaluation indicators included anatomic variations, maxillary sinus volume, and nasal meatus-related parameters in 45 children and 82 adults, which were evaluated twice by 3DSlicer software. Parameters were assessed using the Kolmogorov-Smirnov test, followed by paired t-test and Chi-squared test for multiple comparisons.
    UNASSIGNED: Significant differences were found in the accessory maxillary ostium (AMO) and maxillary sinus retention cyst between two sides (both P<0.001). Maxillary sinus volume and sex had an association of statistical significance on adults\' ACP side (P=0.026) and non-antrochoanal polyp (non-ACP) side (P=0.032). The affected side\'s maxillary sinus volume was significantly larger than the healthy side (P<0.001). The length from the maxillary sinus orifice to the plane of the most lateral margin of the middle turbinate of the ACP side was larger than the non-ACP side in children (P=0.044). Males\' length from the maxillary sinus orifice to the plane of the most lateral margin of the middle turbinate of the ACP side was considerably greater than the healthy side (P<0.001). The length from the maxillary sinus orifice to the plane of the most lateral margin of the middle turbinate (P=0.014) and the length from the inferior turbinate to the nasal septum (P=0.013) on the non-ACP side was higher than the affected side in adults. Males\' length from the inferior turbinate to the nasal septum was higher on the healthy side than the affected side (P<0.001). Males had a greater maximum length from the maxillary sinus lateral wall to the nasal septum (P=0.024) and the length from the inferior turbinate to the nasal septum (P=0.003) on the non-ACP side than females. Males had a larger maximum length from the maxillary sinus lateral wall to the nasal septum on the ACP side than females (P=0.011).
    UNASSIGNED: In our study, the occurrence of the AMO, the maxillary sinus\'s expanded size, and the stenosis of the associated channels around the ostiomeatal complex and common meatus are regarded as probably connected to the formation of ACPs. In addition, the anatomic variations that involve the ostiomeatal complex and may lead to a change in maxillary sinus pressure and nasal ventilation are important factors in the formation of ACPs.
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  • 文章类型: Journal Article
    目的:使用基于MRI的合成CT图像确定轴向脊柱关节炎(axSpA)患者骶髂关节变异的患病率,并评估其与骨髓水肿的关系。因为这可能会使疑似axSpA患者的MRI诊断活动性骶髂关节炎复杂化。
    方法:172例患者被纳入回顾性研究。所有患者均因临床怀疑骶髂关节炎而接受MRI检查。axSpA的诊断是由三级医院风湿病学家做出的。两名读者独立地确定了骨髓水肿的存在以及九种已知的骶髂关节(SIJ)变体中的一种或多种的存在。
    结果:SIJ变异在axSpA患者(82.9%)和非SpA组(85.4%)中很常见;患病率无显著差异。骨髓水肿常见于axSpA(86.8%)和非SpA(34%)患者。具有SIJ变异的AxSpA患者(除了附属关节)表现出4至10倍的骨髓水肿几率,但没有统计学意义。该组中存在的变体越多,骨髓水肿的几率越高。然而,不能排除一些多重共线性,因为根据定义,axSpA组的骨髓水肿非常常见。
    结论:SIJ变异在axSpA和非SpA患者中是常见的。SIJ变异与axSpA患者骨髓水肿患病率较高相关,可能是由于生物力学的改变,可用作稳定器的附件接头除外。
    OBJECTIVE: To determine the prevalence of sacroiliac joint variants in patients with axial spondyloarthritis (axSpA) using MRI-based synthetic CT images and to evaluate their relationships with the presence of bone marrow edema, as this may potentially complicate diagnosing active sacroiliitis on MRI in patients with suspected axSpA.
    METHODS: 172 patients were retrospectively included. All patients underwent MRI because of clinical suspicion of sacroiliitis. The diagnosis of axSpA was made by a tertiary hospital rheumatologist. Two readers independently determined the presence of bone marrow edema and the presence of one or more of the nine known sacroiliac joint (SIJ) variants.
    RESULTS: SIJ variants were common in axSpA patients (82.9%) and the non-SpA group (85.4%); there were no significant differences in prevalence. Bone marrow edema was frequently found in axSpA (86.8%) and non-SpA patients (34%). AxSpA patients with SIJ variants (except for accessory joint) demonstrated 4 to 10 times higher odds for bone marrow edema, however not statistically significant. The more variants were present in this group, the higher the chance of bone marrow edema. However, some multicollinearity cannot be excluded, since bone marrow edema is very frequent in the axSpA group by definition.
    CONCLUSIONS: SIJ variants are common in axSpA and non-SpA patients. SIJ variants were associated with higher prevalence of bone marrow edema in axSpA patients, potentially due to altered biomechanics, except for accessory joint which may act as a stabilizer.
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