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  • 文章类型: Journal Article
    背景:颈部肌肉脂肪浸润和/或肌肉体积的变化可以改变颈椎排列和颅骨负荷分布,这可能会导致口面区域的疼痛。
    目的:这项研究的目的是检查颞下颌关节紊乱病(TMD)患者颈部肌肉的肌肉体积和脂肪浸润。
    方法:本病例对照研究包括18例TMD患者和18例年龄和性别匹配的对照。使用磁共振成像(MRI)和ITK-SNAP软件测量参与者颈部肌肉的肌肉体积和脂肪浸润。胸锁乳突(SCM)的3D模型,脾炎(SPLC),颈半肌(SC)-长半肌(SCP),使用ITK-SNAP创建C3-C7范围内的多裂(M)肌肉,半自动分割软件。模型用于确定体积和脂肪浸润水平。颈部残疾指数(NDI)用于评估颈部疼痛相关的残疾。TMD的严重程度是使用Fonseca记忆指数(FAI)确定的,而颌骨相关残疾用颌骨功能限制量表-20(JFLS-20)测量。使用数字评定量表(NRS)记录休息时和咀嚼期间的疼痛水平。
    结果:总肌肉体积无统计学差异,SCM的脂肪渗透量和脂肪渗透百分比,SPLC,SCP,SC,两组之间的M肌肉(p>0.05)。与对照组相比,患者组的NDI评分更高(p<0.001)。NDI评分与JFLS-20呈正相关(r=0.831,p<0.001),休息时(r=0.753,p<0.001)和咀嚼时(r=0.686,p<0.001)的FAI(r=0.815,p<0.001)和NRS评分。
    结论:本研究未发现TMD患者和对照组之间颈部肌肉体积或脂肪浸润的任何显著差异。然而,颈部残疾的严重程度与下颌功能有关,疼痛和TMD水平。
    BACKGROUND: Changes in the fatty infiltration and/or muscle volume of neck muscles can alter cervical spine alignment and cranial load distribution, which may cause pain in the orofacial region.
    OBJECTIVE: The aim of the study was to examine the muscle volume and fatty infiltration of neck muscles in patients with temporomandibular disorders (TMD).
    METHODS: This case-control study included 18 patients with TMD and 18 ageand sex-matched controls. The muscle volume and fatty infiltration of the neck muscles of the participants were measured using magnetic resonance imaging (MRI) and ITK-SNAP software. The 3D models of the sternocleidomastoid (SCM), splenius capitis (SPLC), semispinalis cervicis (SC)-semispinalis capitis (SCP), and multifidus (M) muscles within the C3-C7 range were created using ITK-SNAP, a semi-automatic segmentation software. The models were used to determine the volumes and fatty infiltration levels. The Neck Disability Index (NDI) was used to assess neck pain-related disability. The severity of TMD was determined using the Fonseca Anamnestic Index (FAI), while jaw-related disability was measured with the Jaw Functional Limitation Scale-20 (JFLS-20). Pain levels were recorded at rest and during chewing using the numeric rating scale (NRS).
    RESULTS: There were no statistically significant differences in total muscle volume, fatty infiltration volume and fatty infiltration percentage of the SCM, SPLC, SCP, SC, and M muscles between the 2 groups (p > 0.05). The patient group had higher NDI scores compared to the controls (p < 0.001). The NDI scores correlated positively with the JFLS-20 (r = 0.831, p < 0.001), FAI (r = 0.815, p < 0.001) and NRS scores at rest (r = 0.753, p < 0.001) and during chewing (r = 0.686, p < 0.001).
    CONCLUSIONS: The present study did not identify any significant differences in the neck muscle volume or fatty infiltration between the TMD patients and controls. However, the severity of neck disability was found to correlate with jaw function, pain and TMD levels.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Journal Article
    肱骨近端骨折是65至89岁患者的第三大常见骨折类型,女性比男性更常见。鉴于肱骨近端骨折的手术治疗方法多种多样,这项研究的目的是(1)报告美国国家对肱骨近端骨折手术治疗的数量和发生率估计,以更好地了解过去十年中不断变化的实践;(2)分析年龄组之间的数量和发生率差异,性别,和地理区域。
    使用IBMMarketscan国家数据库,所有接受切开复位内固定(ORIF)的患者,半髋关节置换术,2010年至2019年期间或反向全肩关节置换术(RTSA)与当前程序术语代码一起确定。进一步对数据集进行分层,以确定接受肱骨近端骨折治疗的患者。IBMMarketscan提供了排放重量,用于确定IBMSPSSStatistics软件中每个程序的国家年度估算量(IBMCorp.,Armonk,NY,美国)。每1,000,000人调整数量和发病率,并根据年龄组计算亚组,性别,和地理区域。美国人口普查局的年度人口数据用于所有发病率计算。
    在过去的十年中,手术治疗的肱骨近端骨折的总体积和发生率分别增加了13%和5%,分别。虽然总体发病率下降,ORIF仍然是最常见的手术治疗方法。ORIF的体积和发生率的最大下降发生在≥75的患者中。ORIF治疗的发病率在南部和西部增加,而在东北部和中西部减少。2010年至2019年间,HA的总量和发病率下降,并且在所有亚组中都保持这种趋势。RTSA的总体积和发生率增加了300%以上。接受RTSA的男性和女性的发病率分别增加了266%和320%,分别。RTSA的体积和发病率在所有年龄组都增加。中西部地区RTSA的数量和发病率增加,南,和西部地区,而东北地区保持不变。
    肱骨近端骨折的手术治疗趋势在过去十年中发生了很大变化。ORIF仍然是肱骨近端骨折最常见的手术治疗方法。HA已失宠,而RTSA的性别使用量显着增加,年龄组,和地理区域。这些趋势代表了在选择手术治疗时,通过考虑所有患者和骨折特征来治疗肱骨近端骨折的实践变化。
    UNASSIGNED: Proximal humerus fractures are the third most common fracture type for patients between the ages of 65 and 89 and occur more frequently in women than men. Given the variety of surgical treatments for proximal humerus fractures, the aim of this study was to (1) report United States national volume and incidence estimates for surgical management of proximal humerus fractures to better understand the changing practice over the past decade and (2) to analyze differences in volume and incidence among age groups, sex, and geographic region.
    UNASSIGNED: Using IBM Marketscan national database, all patients that underwent open reduction internal fixation (ORIF), hemiarthroplasty, or reverse total shoulder arthroplasty (RTSA) between 2010 and 2019 were identified with Current Procedural Terminology codes. The dataset was further stratified to identify patients treated for proximal humerus fractures. IBM Marketscan provided discharge weights that were used to determine estimated national annual volumes of each procedure in IBM SPSS Statistics software (IBM Corp., Armonk, NY, USA). Volume and incidence were adjusted per 1,000,000 persons and calculated for subgroups according to age group, sex, and geographical region. The United States Census Bureau annual population data was used for all incidence calculations.
    UNASSIGNED: Over the past decade, the total volume and incidence of surgically treated proximal humerus fractures increased by 13% and 5%, respectively. Although overall incidence decreased, ORIF remained the most common surgical treatment. The greatest decrease in volume and incidence of ORIF occurred in patients ≥75. The incidence of ORIF treatment increased in the South and West while it decreased in the Northeast and Midwest. Total volume and incidence of HA decreased between 2010 and 2019 and this trend remained among all subgroups. Total volume and incidence of RTSA increased by over 300%. The incidence of males and females receiving RTSA increased by 266% and 320%, respectively. Volume and incidence of RTSA increased across all age groups. Volume and incidence of RTSA increased in the Midwest, South, and Western regions while it remained unchanged in the Northeast.
    UNASSIGNED: Surgical management trends of proximal humerus fractures have changed greatly over the past decade. ORIF remains the most common surgical treatment for proximal humerus fractures. HA has fallen out of favor while RTSA has seen significant increases in usage across sex, age groups, and geographic regions. These trends represent a change in practice for treating proximal humerus fractures by considering all patient and fracture characteristics when opting for surgical management.
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  • 文章类型: Journal Article
    UNASSIGNED:开发和验证基于胃腺癌(GA)的大体肿瘤体积(GTV)对应于多探测器计算机断层扫描(CT)测量的N期的定量模型,用于术前确定可切除性。
    UNASSIGNED:在治疗前两周接受对比增强CT的493例确诊为GA的连续患者随机纳入训练队列(TC,n=271),内部验证队列(IVC,n=107)和外部验证队列(EVC,n=115)。通过将所有肿瘤面积的总和乘以切片厚度在CT上测量GTV。在TC,进行了单因素和多因素分析,以选择与可切除性相关的因素.接收器工作特性(ROC)分析是为了确定基于N级的GTV是否可以识别可切除性。在IVC和EVC中,未加权科恩的Kappa检验是为了评估ROC模型的性能。
    未经评估:根据单变量分析,年龄,cT阶段,cN分期和GTV与TC可切除性相关(P值均<0.05),多变量分析表明,cN分期和GTV是独立的危险因素,比值比为1.594(95%置信区间[CI]:1.105-2.301)和1.055(95CI:1.035-1.076)。分别。TC的ROC分析显示,截止值分别为21.81、21.70和36.93cm3,以区分cN0-3,cN2和cN3阶段的可切除和不可切除的癌症,曲线下面积分别大于0.8,这在IVC和EVC中得到了验证,平均Cohenk值超过0.72。
    UNASSIGNED:GTV和cN分期可能是无法切除的GA的独立危险因素,基于N级的GTV可以帮助确定可切除性。
    UNASSIGNED: To develop and validate a quantitative model based on gross tumor volume (GTV) of gastric adenocarcinoma (GA) corresponding to N-stage measured at multidetector computed tomography (CT) for preoperative determination of resectability.
    UNASSIGNED: 493 consecutive patients with confirmed GA undergoing contrast-enhanced CT two weeks before treatments were randomly enrolled into the training cohort (TC, n = 271), internal validation cohort (IVC, n = 107) and external validation cohort (EVC, n = 115). GTV was measured on CT by multiplying sums of all tumor areas by section thickness. In TC, univariate and multivariate analyses were performed to select factors associated with resectability. Receiver operating characteristic (ROC) analysis was to determine if N-stage based GTV could identify resectability. In IVC and EVC, unweighted Cohen\'s Kappa tests were to evaluate performances of the ROC models.
    UNASSIGNED: According to univariate analysis, age, cT stage, cN stage and GTV were related to resectability in TC (all P-values < 0.05), and multivariate analysis suggested that cN stage and GTV were independent risk factors with odds ratios of 1.594 (95% confidence interval [CI]: 1.105-2.301) and 1.055 (95%CI: 1.035-1.076), respectively. ROC analysis in TC revealed the cutoffs of 21.81, 21.70 and 36.93 cm3 to differentiate between resectable and unresectable cancers in stages cN0-3, cN2 and cN3 with areas under the curves of more than 0.8, respectively, which was validated in IVC and EVC with average Cohen k-values of more than 0.72.
    UNASSIGNED: GTV and cN stage can be independent risk factors of unresectable GA, and N-stage based GTV can help determine resectability.
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  • 文章类型: Journal Article
    尽管人们普遍认识到髋部骨折患者的髋部BMD降低,有和没有髋部骨折的受试者在诸如皮质体积和厚度等几何参数上的差异并不为人所知。
    这项横断面研究包括了5162名社区居住的老年妇女进行了髋关节CT扫描,其中236人患有急性髋部骨折。326名年龄匹配的无髋部骨折妇女作为对照。使用MIAF-股骨软件测量髋部骨折患者的完整对侧股骨和对照组的左股骨。总髋关节(TH)的积分和皮质体积(Vols),股骨头(FH),股骨颈(FN),对转子(TR)和转子间(IT)进行分析。在FH和FN中,体积进一步细分为上前(SA)和后(SP)以及下前(IA)和后(IP)象限。测定上面列出的所有感兴趣的子体积(VOI)的皮质厚度(CortThick)。
    对照组和骨折组的平均年龄分别为71.7和72.0岁,分别。除TRVol外,骨折患者的所有VOI的CortThick和Vol均显着降低。在骨折患者中,除象限SA的皮质体积外,所有象限中FN的皮质厚度和体积均显着降低(p=0.635)。髋部骨折患者在调整年龄前后的整体FN体积和横截面积(CSA)较小,身高和体重。关于髋部骨折的辨别,整个股骨近端的皮质体积比皮质厚度差。Cort/TrabMass比值(RCTM),测量骨骼的内部分布,在区分髋部骨折风险方面优于皮质厚度。对于包含THCortThick的模型,获得了最高的曲线下面积(AUC)值0.805,FHVol,THRCTM和FNCSA。
    股骨近端骨折和未骨折的女性在总体积和皮质体积以及皮质厚度方面存在显著差异。几何变量的组合对髋部骨折风险的辨别能力与aBMD相似。
    Although it is widely recognized that hip BMD is reduced in patients with hip fracture, the differences in geometrical parameters such as cortical volume and thickness between subjects with and without hip fracture are less well known.
    Five hundred and sixty two community-dwelling elderly women with hip CT scans were included in this cross-sectional study, of whom 236 had an acute hip fracture. 326 age matched women without hip fracture served as controls. MIAF-Femur software was used for the measurement of the intact contralateral femur in patients with hip fracture and the left femur of the controls. Integral and cortical volumes (Vols) of the total hip (TH), femoral head (FH), femoral neck (FN), trochanter (TR) and intertrochanter (IT) were analyzed. In the FH and FN the volumes were further subdivided into superior anterior (SA) and posterior (SP) as well as inferior anterior (IA) and posterior (IP) quadrants. Cortical thickness (CortThick) was determined for all sub volumes of interest (VOIs) listed above.
    The average age of the control and fracture groups was 71.7 and 72.0 years, respectively. The fracture patients had significantly lower CortThick and Vol of all VOIs except for TRVol. In the fracture patients, cortical thickness and volume at the FN were significantly lower in all quadrants except for cortical volume of quadrant SA (p= 0.635). Hip fracture patients had smaller integral FN volume and cross-sectional area (CSA) before and after adjustment of age, height and weight. With respect to hip fracture discrimination, cortical volume performed poorer than cortical thickness across the whole proximal femur. The ratio of Cort/TrabMass (RCTM), a measure of the internal distribution of bone, performed better than cortical thickness in discriminating hip fracture risk. The highest area under curve (AUC) value of 0.805 was obtained for the model that included THCortThick, FHVol, THRCTM and FNCSA.
    There were substantial differences in total and cortical volume as well as cortical thickness between fractured and unfractured women across the proximal femur. A combination of geometric variables resulted in similar discrimination power for hip fracture risk as aBMD.
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  • 文章类型: Journal Article
    This paper provides new evidence on the link between patient outcome and physician experience. Using birth certificates data from a large hospital in Italy, I analyze whether cesarean section surgeons who have performed more procedures in the recent past observe an improvement in performance. By using data from the Italian health care system, where patients are not allowed to choose their physician, I lower concerns of potential reverse causality (selective referral). I find evidence indicating a strong learning-by-doing effect: for emergent cases, a one standard deviation increase in recent experience reduces the likelihood of neonatal intensive care unit admission by nearly 3.2 percentage points (13.8%) and of being born with a low Apgar Score by about 1.9 percentage points (13.2%), all else equal. This effect is not present for the case of elective C-sections.
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  • 文章类型: Journal Article
    Individual tree structural parameters are vital for precision silviculture in planted forests. This study used near-field LiDAR (light detection and ranging) data (i.e., unmanned aerial vehicle laser scanning (ULS) and ground backpack laser scanning (BLS)) to extract individual tree structural parameters and fit volume models in subtropical planted forests in southeastern China. To do this, firstly, the tree height was acquired from ULS data and the diameter at breast height (DBH) was acquired from BLS data by using individual tree segmentation algorithms. Secondly, point clouds of the complete forest canopy were obtained through the combination of ULS and BLS data. Finally, five tree taper models were fitted using the LiDAR-extracted structural parameters of each tree, and then the optimal taper model was selected. Moreover, standard volume models were used to calculate the stand volume; then, standing timber volume tables were created for dawn redwood and poplar. The extraction of individual tree structural parameters exhibited good performance. The volume model had a good performance in calculating the standing volume for dawn redwood and poplar. Our results demonstrate that near-field LiDAR has a strong capability of extracting tree structural parameters and creating volume tables for subtropical planted forests.
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  • 文章类型: Journal Article
    Prostate cancer presents a significant challenge and burden for health care centres across the world. In the UK and other parts of Europe, as well as areas of the USA, centralisation of services has been implemented. In the UK and Europe, hospital centres are split into a hub-and-spoke system. High-volume centres carry out treatment as hubs and local hospitals carry out diagnostics and referrals as spokes. In this narrative mini-review we evaluate whether centralisation of services has improved patient outcomes, streamlined the use of resources, and reduced costs. We also discuss the positive and negative impacts of centralisation of prostate cancer services. PATIENT SUMMARY: This mini-review discusses the current use of centralisation of prostate cancer services. We assess the evidence in favour of centralisation as well as the issues it can present to both health care systems and patients.
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  • 文章类型: Journal Article
    To elaborate efficient and economical water supply systems is one of the main objectives in the sanitation companies water system projects. In order to address the challenges faced in reaching this objective, this study aims to identify, first, the relation between the percentage of non-conformed samples in treated water and the inefficiency of the filtering units installed in the water treatment plant, and second, if, by drawing the consumption variation curve it is the most efficient way to predict the storage tanks volume-comparing necessary capacity, determined by the consumption curve, and installed capacity, predict by the outdated Brazilian normative. In order to reach answers for these two questions, this study measured the operating efficiency of the treatment plant as well as have set a quantitative comparison between the two dimensioning criteria for storage tanks volume present in the literature. As a result, the analysis provided the authors to detect a focus of contamination in the single-layered filtering units, limited by the filtering capacity of 2-6 m3/(m2 day), whilst operating at 333.13 m3/(m2 day). As well as to detect by the drawing of the consumption variation curve an oversize of 68% and 60% in the dimensioning of the studied storage tanks. With the results provided by this analysis approach, it was possible to efficiently detect and correct critical impairments in the treatment phase and to conclude that a long-term analysis should be drawn in order to affirm if the consumption variation curve is the best design methodology for the reservoirs.
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  • 文章类型: Journal Article
    OBJECTIVE: To determine whether the changing cardiac landscape has affected traditional cardiothoracic surgery (CTS) resident case volume, particularly cardiac case volume.
    METHODS: The Accreditation Council for Graduate Medical Education (ACGME) case logs for traditional CTS residents from 2016 to 2019 were reviewed. Using linear and nonlinear regression, trends in the annual volume and proportion of CTS operations were examined.
    RESULTS: Overall, the average number of total and category-specific CTS resident cases have increased from 2016 to 2019. However, in general, the proportion of thoracic surgery cases has been increasing, and the proportion of cardiac surgery cases has been decreasing. In particular, the proportion of coronary atherosclerosis (-0.2546 per 100 cases/year; P < .001) and valvular heart disease (-0.319 per 100 cases/year; P < .001) procedures demonstrated the greatest downward trends. The average operative experience for residents has increased (28.8 cases/resident/year; P < .001), but cardiac track residents (22.24 cases/resident/year; P < .001) have had a smaller increase than thoracic track residents (35.04 cases/resident/year; P < .001). Nevertheless, cardiac track residents experienced an increase in their average proportion of cardiac cases (0.176 per 100 cases/year; P < .001) compared with average (-0.263 per 100 cases/year; P < .001) and thoracic track (-0.978 per 100 cases/year; P < .001) CTS residents, indicating specialization of the tracks.
    CONCLUSIONS: The overall CTS resident operative experience has increased over the last several years, with cardiac cases increasing more slowly than thoracic cases. The analysis reveals that cardiac operative volume has been asymmetrically allocated to cardiac track residents, indicating a greater specialization of the tracks. Annual evaluation of CTS resident case volume will provide essential insight into the field.
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