BACKGROUND: Vitiligo can be challenging to treat and exhibit an unpredictable clinical course. Phototherapy in the form of visible light can achieve both repigmentation and depigmentation outcomes in vitiligo, with minimal associated adverse events. This review focuses on the mechanistic understandings and clinical outcomes of visible light-based treatments for vitiligo.
METHODS: Articles were retrieved from PubMed starting from May 1965 until August 2023, yielding 496 unique articles. We conducted title, abstract, and full-text screening to identify articles describing the use of visible light (380-750 nm), either as part of combination therapy or as monotherapy, for repigmentation or depigmentation treatment in vitiligo.
RESULTS: Twenty-seven articles met inclusion criteria, offering preclinical and clinical data regarding the utilization of helium-neon laser (red light) and blue light-emitting diodes (LEDs) as methods of repigmentation therapy in vitiligo. Preclinical and clinical data on the utilization of Q-switched ruby laser (694 nm) and frequency-doubled (FD) Nd:YAG laser (532 nm) for vitiligo depigmentation therapy were also identified.
CONCLUSIONS: While limited by small studies and a lack of standardized administration of phototherapy, the evidence for visible light\'s effectiveness in managing vitiligo is encouraging. Red light therapy using He-Ne lasers and blue light therapy via LEDs can stimulate repigmentation in patients with vitiligo with minimal adverse events. Q-switched ruby and FD Nd:YAG lasers provide viable, visible light depigmentation options, either alone or with topical agents. With limited clinical data, larger studies are needed to validate the efficacy of visible light therapy in treating vitiligo and to better understand its long-term outcomes.

Harmful algal blooms have raised great concerns due to their adverse effects on aquatic ecosystems and human health. Recently, visible light-driven (VLD) photocatalysis has attracted attention for algae inactivation owing to its unique characteristics of low cost, mechanical stability, and excellent removal efficiency. However, the low utilization of visible light and the high complexation rate of electron-hole (e--h+) pairs are essential drawbacks of conventional photocatalysts. Scientific efforts have been devoted to modifying VLD photocatalysts to enhance their antialgal activity. This review concisely summarizes the anti-algae performance of the latest modified VLD photocatalysts. The summary of the mechanisms in VLD photocatalytic inactivation demonstrates that reactive oxygen species (ROS) can induce oxidative damage to algal cells and photocatalytic degradation of released organic matter. In addition, the factors, such as photocatalyst dosage, algal concentration and species, and the physicochemical properties of different water matrices, such as pH, natural organic matter, and inorganic ions, affecting the efficacy of VLD catalytic oxidation for algae removal are briefly outlined. Thereafter, this review compiles perspectives on the emerging field of VLD photocatalytic inactivation.

The scientific data review shows that advanced oxidation processes based on the hydroxyl or sulfate radicals are of great interest among the currently conventional water and wastewater treatment methods. Different advanced treatment processes such as photocatalysis, Fenton\'s reagent, ozonation, and persulfate-based processes were investigated to degrade contaminants of emerging concern (CECs) such as pesticides, personal care products, pharmaceuticals, disinfectants, dyes, and estrogenic substances. This article presents a general overview of visible light-driven advanced oxidation processes for the removal of chlorfenvinphos (organophosphorus insecticide), methylene blue (azo dye), and diclofenac (non-steroidal anti-inflammatory drug). The following visible light-driven treatment methods were reviewed: photocatalysis, sulfate radical oxidation, and photoelectrocatalysis. Visible light, among other sources of energy, is a renewable energy source and an excellent substitute for ultraviolet radiation used in advanced oxidation processes. It creates a high application potential for solar-assisted advanced oxidation processes in water and wastewater technology. Despite numerous publications of advanced oxidation processes (AOPs), more extensive research is needed to investigate the mechanisms of contaminant degradation in the presence of visible light. Therefore, this paper provides an important source of information on the degradation mechanism of emerging contaminants. An important aspect in the work is the analysis of process parameters affecting the degradation process. The initial concentration of CECs, pH, reaction time, and catalyst dosage are discussed and analyzed. Based on a comprehensive survey of previous studies, opportunities for applications of AOPs are presented, highlighting the need for further efforts to address dominant barriers to knowledge acquisition.

BACKGROUND: The growing use of electronic devices and other artificial light sources in recent decades has changed the pattern of exposure to blue light (400-500 nm). Although some progress has been made in the study of the biological effects of blue light on the skin, many questions in this field remain unexplored. The aim of this article was to review the currently available evidence on the deleterious effects of blue light on the skin as well as the methods and strategies designed to protect from the detrimental effects of blue light. The PubMed and ProQuest databases were searched in January 2022. Search results were supplemented by articles considered relevant by the authors.
CONCLUSIONS: The results of in vitro, in vivo, and clinical studies show that blue light produces direct and indirect effects on the skin. The most significant direct effects are the excessive generation of reactive oxygen and nitrogen species, and hyperpigmentation. Reactive oxygen and nitrogen species cause DNA damage and modulate the immune response. Indirect effects of blue light include disruption of the central circadian rhythm regulation via melatonin signaling and local circadian rhythm regulation via direct effects on skin cells. Antioxidants and sunscreens containing titanium dioxide, iron oxides, and zinc oxide can be used to protect against the detrimental effects of blue light as part of a strategy that combines daytime protection and night-time repair.
CONCLUSIONS: Blue light produces a wide variety of direct and indirect effects on the skin. As exposure to blue light from artificial sources is likely to continue to increase, this area warrants further investigation.

In recent years, carbon quantum dots (CQDs) have received widespread attention owing to their non-toxicity, sustainability, excellent photostability, and intrinsic photoluminescence properties. In particular, CQDs have attracted considerable interest for visible-light-driven photocatalysis because of their excellent electron transfer characteristics and high light capture efficiency. Many studies have reported CQDs/photocatalyst composite systems constructed to make full use of the solar spectrum, improving the ability of photocatalytic materials to degrade organic pollutants. Here, we review the recent research on CQDs-based photocatalysts, and their ability to remove environmental pollutants, with a special emphasis on degradation mechanisms. Several improvements in the catalytic response of CQDs to visible light are also included. In addition, we discuss the aspects that should be considered to construct composite materials based on CQD characteristics and the potential applications of CQD-based photocatalysts for efficient utilization of visible light.

Bismuth-based composite materials have unique structural, chemical, optical, and electrical properties that are highly beneficial in Photocatalysis. The layered structure and tunable bandgap properties of the Bismuth-based composites are advantageous for the absorption of solar light efficiently. Also, these properties help the separation and recombination of photogenerated charge carriers, leading to enhancement in the photocatalytic activity. Synthesis of the catalyst at a lower temperature to produce catalyst reduces the production cost and electrical energy consumption. This review provides an overview of the recent development in Bismuth-based composite nanostructured photocatalytic materials, mainly using low-temperature driven synthesis methods. Herein, we have mainly summarized the primarily used low temperature-based synthetic routes, particularly in the temperature range of 50-300 °C for synthesizing Bismuth-based composite materials. In addition to this, the photocatalytic mechanism, the textural, structural, electronic, and photocatalytic properties of the synthesized photocatalysts are discussed. The literature shows that the surface area of the composite Bismuth-based photocatalytic materials synthesized using the low-temperature synthetic route is in the range of 1.5-81 m2/g and can be activated by solar, ultraviolet, and Light Emitting Diode (LEDs) light irradiation based on the synthetic route. Their photocatalytic performance and structural stability are excellent and utilized for several runs. The comprehensive understanding of the low-temperature synthesis of Bismuth-based composite materials for visible light-activated photocatalytic applications provided will be useful for developing photocatalytic materials on an industrial scale due to energy-efficient synthetic routes. Furthermore, the prospects of low temperature-driven Bismuth-based composite synthesis routes are discussed.

Photocatalysis is a green approach frequently utilised to eliminate a variety of environmentally hazardous refractory pollutants. Accordingly, the modification of semiconductor photocatalysts with Carbon Quantum Dots (CQDs) is of great importance for the treatment of such pollutants due to their attractive physical and chemical properties. CQDs are a perfect candidate to handle photocatalysts of high-performance since they operate as co-catalysts and as visible light harvesters. The higher separation rate of electron-hole pairs in the photocatalytic system is attributable to better photodegradation efficiency. This review classifies CQD based photocatalysts as pure, doped and composite materials and discusses the specific advantages of CQDs in visible light-driven photocatalysis. In this work, the versatile roles of CQDs in CQD-based photocatalytic systems are thoroughly discussed and summarised.

Clothing is recognized by leading health agencies as a primary method to protect against the harmful effects of photodamage caused by ultraviolet (UV) radiation and visible light. The photoprotective capacity of clothing is commonly measured as the ultraviolet protective factor (UPF). While the technology driving photoprotective clothing has been well-established, there continues to be efforts to discover new materials to improve the UPF of clothing. Here, we show increased Google searches for photoprotective clothing over the last decade, suggesting a high level of public interest in photoprotective clothing. In addition, we investigate the frequency of UPF-graded photoprotective clothing sold by large retail stores featured in Fortune 1000. We review factors that alter the UPF of clothing and describe emerging textile technologies used to increase clothing\'s photoprotective capacity. Finally, we compare how photoprotective clothing is regulated among different countries, the importance of photoprotective clothing in occupational health, and research in visible light and clothing photoprotection.

Social distancing is conducive to grow the impact of artificial light in the daily life of the worldwide population with reported consequences to the skin. Sunlight is also essential for human development, indeed, solar radiation is composed of different types of wavelengths, which generate different skin effects. It can be divided into ultraviolet (UV), infrared (IR), and visible. UV radiation (UVA and UVB) has cutaneous biological effects ranging from photoaging, immunosuppression to melanoma formation, through the production of reactive oxygen species (ROS), inflammation and elevation of the energy state of organic molecules, changing the DNA structure. IR radiation reaches deeper layers of the skin and is also related to the generation of ROS, photoaging and erythema while visible light is responsible for generating ROS, pigmentation, cytokine formation, and matrix metallopeptidases (MMPs). Furthermore, artificial light could be harmful to the skin, as it can generate ROS, hyperpigmentation, and stimulate photoaging. Currently, we briefly summarized the cutaneous biological effects of sunlight, as well as artificial light on skin and remarked the opportunity of the evolution of current photoprotective formulas through new strategies with broad spectrum protection.

Photocatalysis has emerged as an environmentally friendly approach for microbial disinfection. The development of visible-light-driven (VLD) photocatalysts for water pollution remediation is imperative, considering that visible light constitutes a substantial fraction of the solar spectrum. The modification of photocatalysts by Ag/AgX (X = Cl, Br, I) deposition can be used to improve photocatalytic efficiencies. This is achieved by preventing photogenerated electron-hole pairs recombination through electron trapping mechanisms. With the introduction of silver NPs, visible light absorption can also be increased through its SPR enhancement. Silver also possesses excellent antimicrobial properties. Consequently, a novel class of Ag/AgX-containing hybrid materials has recently emerged as a promising candidate for water disinfection. This review summarizes the latest advances in the synthesis of Ag/AgX-containing photocatalysts using various synthetic methods. The microbial disinfection efficiencies of the as-prepared materials, the main reactive oxygen species and disinfection mechanisms are also reviewed in detail. Finally, some areas that need to be improved are discussed along with new insights as perspectives for future developments in this field.