urinary retention

尿潴留
  • 文章类型: Journal Article
    目的:这项随机对照试验的目的是评估在有尿潴留风险的男性患者在胃肠道手术中硬膜外麻醉期间早期拔除导尿管是否可行。
    方法:本随机对照试验纳入接受胃癌或结肠癌根治术的男性患者。患者以1:1随机分为2组:早期组,其中在术后第二天或第三天拔除硬膜外导管之前拔除导尿管,和后期小组,其中拔除硬膜外导管后拔除导尿管。随机化调整因素为年龄(≥65岁或<65岁)和手术部位(胃或结肠)。主要终点是尿潴留。次要终点是尿路感染的发生率和术后住院时间。
    结果:在2020年3月至2024年2月之间招募了73名患者,分为早期(n=37)和晚期(n=36)组。4名患者在随机分组后撤回了他们的同意书。意向治疗分析显示,早期组4例(11.1%)和晚期组1例(3.0%)发生尿潴留(P=0.20)。晚期尿路感染1例(3.0%)。两组的中位术后住院时间均为9天。
    结论:在接受硬膜外麻醉的胃肠手术的男性患者中,早期拔除导尿管可在预期可接受范围内增加尿潴留。
    背景:UMIN000040468,注册日期:2020年5月21日。
    OBJECTIVE: The purpose of this randomized controlled trial was to evaluate whether early urinary catheter removal is feasible during epidural anesthesia during gastrointestinal surgery in male patients at high risk for urinary retention.
    METHODS: Male patients who underwent radical surgery for gastric or colon cancer were enrolled in this randomized controlled trial. Patients were randomized 1:1 into 2 groups: the early group, in which the urinary catheter was removed before removal of the epidural catheter on the second or third postoperative day, and the late group, in which the urinary catheter was removed after removal of the epidural catheter. The randomization adjustment factors were age (≥ 65 or < 65 years) and operative site (gastric or colon). The primary endpoint was urinary retention. The secondary endpoints were the incidence of urinary tract infection and length of postoperative hospital stay.
    RESULTS: Seventy-three patients were enrolled between March 2020 and February 2024 and assigned to the Early (n = 37) and Late (n = 36) groups. Four patients withdrew their consent after randomization. The intention-to-treat analysis showed that urinary retention occurred in 4 patients (11.1%) in the early group and 1 patient (3.0%) in the late group (P = 0.20). Urinary tract infection occurred in 1 patient (3.0%) in the late group. The median postoperative hospital stay was 9 days in both groups.
    CONCLUSIONS: Early urinary catheter removal in male patients undergoing gastrointestinal surgery with epidural anesthesia could increase urinary retention within the expected acceptable range.
    BACKGROUND: UMIN000040468, Date of registration: May 21, 2020.
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  • 文章类型: Journal Article
    尿潴留是导致患者疼痛和不适的术后问题,即使使用导管。磁疗在通过穴位治疗术后尿潴留中的潜在作用仍不确定。这项研究旨在评估磁疗对手术患者尿潴留的影响。
    这项单盲临床试验研究在手术室的康复部门进行,随后在阿明医院的外科部门进行。该研究于2022年在伊斯法罕进行,使用简单随机抽样方法选择了64名患者,并将其平均分为两组。在干预组中,应用了磁铁板,而对照组在七个特定点接受铁板,持续时间为35±5分钟。人口统计信息,尿液排泄的类型,尿潴留的持续时间,使用研究者编制的干预组和对照组的检查表记录排泄尿量.比较这些数据并进行描述性和分析性统计分析。
    在参与者中(N=64),大多数是男性(N=37,57.80%),平均年龄为40.17岁。卡方分析显示,干预组和对照组在尿排泄类型方面没有显着差异(p=0.106)。然而,Mann-WhitneyU检验显示两组之间在消除尿潴留所需持续时间和排尿量方面存在显著差异(F2,41=62和F1,76=62;p<0.001).
    已证明,将磁疗应用于针灸和反射点的新颖方法可减少首次排尿所需的时间,并增加术后患者的尿量。
    UNASSIGNED: Urinary retention is a postoperative problem that causes pain and discomfort for patients, even when catheters are used. The potential role of magnetic therapy in treating postoperative urinary retention through acupuncture points remains uncertain. This research aims to assess the impact of magnetic therapy on urinary retention in patients undergoing surgery.
    UNASSIGNED: This single-blind clinical trial study was conducted in a recovery department within an operating room and subsequently in the Surgery Department of Amin Hospital. The study took place in Isfahan in 2022, with a sample of 64 patients selected using a simple random sampling method and divided equally into two groups. In the intervention group, magnet plates were applied, while the control group received iron plates at seven specific points for duration of 35 ± 5 minutes. Demographic information, the type of urinary excretion, the duration of urinary retention, and the volume of excreted urine were recorded using a researcher-made checklist for both intervention and control groups. These data were compared and subjected to descriptive and analytical statistical analysis.
    UNASSIGNED: Among the participants (N = 64), the majority were male (N = 37, 57.80%), and the mean age was 40.17 years. The Chi-square analysis revealed no significant difference between the intervention and control groups in terms of the type of urinary excretion (p = 0.106). However, the Mann-Whitney U-test demonstrated significant difference between the two groups regarding the duration required to eliminate urinary retention and the volume of excreted urine (F2,41 = 62 and F1,76 = 62; p < 0.001).
    UNASSIGNED: The use of a novel approach involving magnetic therapy applied to acupuncture and reflexology points has been shown to reduce the time required for the first urination and increase the volume of urine in post-surgery patients.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Journal Article
    目的:根治性子宫切除术是早期宫颈癌的治疗标准,并与术后尿潴留有关。关于减轻术后尿潴留的最佳排尿试验方法尚无明确共识。我们的目的是评估宫颈癌根治性子宫切除术后排尿试验类型与尿潴留风险之间的关系。
    方法:我们对2014年1月至2023年2月因明显早期宫颈癌(FIGO2018分期IA2-IB2)接受根治性子宫切除术的患者进行了回顾性分析。我们根据术后排尿试验的方法比较了尿潴留的发生率和围手术期结局(定时,自动填充,或回填)。多变量逻辑回归用于确定术后30天内空隙试验类型与无尿潴留的相关性。
    结果:在确定的115名患者中,48名(41.8%)患者完成了定时虚空试验,40(34.7%)的自动填空试验,和27(23.5%)的回填空白试验。根据空隙试验,44.3%的患者发生术后尿潴留,没有差异(p=0.17)。对于进行回填排尿试验的患者,尿潴留更有可能在7天(p=0.012)和30天(p=0.01)后消退。与其他试验相比。在多变量模型中,回填空隙试验与没有30天尿潴留相关,与其他试验相比(aOR15.1;95%C.I.1.5-154.9)。
    结论:根据术后空隙试验方法,根治性子宫切除术后尿潴留的发生率没有差异。根治性子宫切除术后的回填空隙试验可能导致术后尿潴留的解决率增加。
    OBJECTIVE: Radical hysterectomy is the standard of care for management of early-stage cervical cancer and is associated with postoperative urinary retention. No clear consensus exists regarding optimal voiding trial methodology for mitigating postoperative urinary retention. Our objective was to evaluate the association between type of postoperative voiding trial and risk of urinary retention after radical hysterectomy for cervical cancer.
    METHODS: We conducted a retrospective analysis of patients undergoing radical hysterectomy for apparent early-stage cervical cancer (FIGO 2018 Stage IA2-IB2) between January 2014 and February 2023. We compared incidence of urinary retention and perioperative outcomes based on method of postoperative voiding trial (timed, autofill, or backfill). Multivariate logistic regression was used to determine association of type of void trial with absence of urinary retention within 30 days postoperatively.
    RESULTS: Of the 115 patients identified, 48 (41.8%) patients completed a timed void trial, 40 (34.7%) an autofill void trial, and 27 (23.5%) a backfill void trial. 44.3% of patients developed postoperative urinary retention with no differences based on void trial (p = 0.17). Urinary retention was more likely to resolve by 7 (p = 0.012) and 30 days (p = 0.01) for patients undergoing backfill voiding trials, compared to other trials. In multivariate models, backfill void trial was associated with absence of 30-day urinary retention, compared to other trials (aOR 15.1; 95% C.I. 1.5-154.9).
    CONCLUSIONS: Rates of urinary retention following radical hysterectomy do not differ based on postoperative void trial methodology. A backfill void trial following radical hysterectomy may lead to increased rates of resolution of postoperative urinary retention.
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  • 文章类型: Journal Article
    比较无导尿管(TWOC)立即试验后建立自发性排尿的成功与男性急性尿retention留的延迟性TWOC。
    在这篇系统综述中,我们纳入了报告在≥18岁男性因急性尿潴留而插管的即时TWOC或延迟TWOC(≤30天)成功率的研究.我们排除了耻骨上导管插入术的研究,术后/围手术期导尿和与创伤相关的尿潴留。我们搜索了以下数据库:MEDLINE,Embase,Cochrane系统评价数据库,Cochrane中央控制试验登记册,打开灰色和Clinicaltrials.gov.搜索于2022年11月30日结束。语言或发布日期没有限制。使用ROB2.0和ROBINS-I工具评估偏倚风险。我们进行了随机效应限制的最大似然模型荟萃分析。使用等级评估证据的确定性。
    我们纳入了61项研究。在两项随机对照试验(RCT)中,都有一些对偏见风险的担忧,包括总共174名参与者,相对成功率为1.22(95%CI0.84-1.76),有利于延迟TWOC。在两项比较队列研究中,两者都有严重的偏见风险,包括642名参与者,相对成功率为1.18(0.94-1.47),有利于延迟TWOC。一项研究由于质量极低而被排除在该荟萃分析之外。四项研究报告了即时TWOC队列的成功率,都有严重的偏见风险,包括409名参与者,总体成功率为47%(29-66)。52项研究报告了TWOC延迟队列的成功率,都有严重的偏见风险,包括12489名参与者,总体成功率为53%(49-56)。证据的确定性被认为是低的RCT和非常低的其余部分。
    有有限数量的适当设计的研究直接解决研究问题。证据都不赞成这两种方法。
    UNASSIGNED: To compare the success of establishing spontaneous micturition following immediate trial without catheter (TWOC) to delayed TWOC in males catheterized for acute urinary retention.
    UNASSIGNED: In this systematic review, we included studies reporting success rates of immediate TWOC or delayed TWOC (≤30 days) among males ≥18 years of age catheterized for acute urinary retention. We excluded studies on suprapubic catheterization, postoperative/perioperative catheterization and urinary retention related to trauma. We searched the following databases: MEDLINE, Embase, Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, Open Grey and Clinicaltrials.gov. The search was concluded on 30 November 2022. There were no restrictions on language or publication date. Risk of bias was assessed using the ROB 2.0 and ROBINS-I tools. We did random-effects restricted maximum likelihood model meta-analyses. Certainty of evidence was assessed using GRADE.
    UNASSIGNED: We included 61 studies. In two randomized controlled trials (RCTs), both with some concerns for risk of bias, including in total 174 participants, the relative success rate was 1.22 (95% CI 0.84-1.76) favouring delayed TWOC. In two comparative cohort studies, both with serious risk of bias, including 642 participants, the relative success rate was 1.18 (0.94-1.47) favouring delayed TWOC. One study was excluded from this meta-analysis because of critically low quality. Four studies reporting success rates for cohorts with immediate TWOC, all with serious risk of bias, including 409 participants, had an overall success rate of 47% (29-66). Fifty-two studies reporting success rates for cohorts with delayed TWOC, all with serious risk of bias, including 12 489 participants, had an overall success rate of 53% (49-56). The certainty of the evidence was considered low for the RCTs and very low for the rest.
    UNASSIGNED: There was a limited number of appropriately designed studies addressing the research question directly. The evidence favours neither approach.
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  • 文章类型: Journal Article
    目的:许多患者在根治性子宫切除术后出现膀胱症状。本研究根据排尿试验(TOV)时间(出院前TOV与出院后TOV)比较了根治性子宫切除术后的尿路结局。
    方法:对2010年1月至2020年1月在两个学术三级转诊中心接受根治性子宫切除术的患者进行了一项回顾性非劣效性研究。根据术后TOV的时间对患者进行分层:出院前或出院后。短期泌尿结果(包括通过TOV,保留表示)和长期从头泌尿功能障碍(定义为刺激性排尿症状,紧迫性,频率,夜尿症,压力或急迫性尿失禁,神经源性膀胱,和/或尿retention留)从病历中提取。我们假设出院前TOV失败的患者比例在出院后TOV的15%非劣效性范围内。
    结果:总共198例患者接受了子宫颈根治性子宫切除术(198例中有118例;59.6%),子宫(198人中有36人;18.2%),和卵巢癌(198人中有29人;14.6%)。119名患者(198人中有119名,占60.1%)接受了出院前TOV,其中119人中有14人(11.8%)失败。出院后TOV患者(198人中有79人,占39.9%),79人中有5人(6.3%)失败。出院前TOV失败的患者比例在非劣效性范围内(差异为5.4%,p=0.23)。出院后TOV组出现长期从头排尿功能障碍的患者比例更高(差异为27.2%,p=0.005)。出院前TOV组诊断新尿路功能障碍的中位时间为0.5年(范围0-9),而出院后TOV组为1.0年(范围0-6)(p>0.05)。
    结论:在这项研究中,出院前TOV的短期结局不差,长期结局改善.
    OBJECTIVE: Many patients develop bladder symptoms after radical hysterectomy. This study compared urinary outcomes following radical hysterectomy based on trial of void (TOV) timing (pre-discharge TOV versus post-discharge TOV).
    METHODS: A retrospective non-inferiority study of patients at two academic tertiary referral centers who underwent radical hysterectomy between January 2010 and January 2020 was carried out. Patients were stratified according to timing of postoperative TOV: either pre-discharge or post-discharge from the hospital. Short-term urinary outcomes (including passing TOV, representation with retention) and long-term de novo urinary dysfunction (defined as irritative voiding symptoms, urgency, frequency, nocturia, stress or urgency incontinence, neurogenic bladder, and/or urinary retention) were extracted from the medical record. We hypothesized that the proportion of patients who failed pre-discharge TOV would be within a 15% non-inferiority margin of post-discharge TOV.
    RESULTS: A total of 198 patients underwent radical hysterectomy for cervical (118 out of 198; 59.6%), uterine (36 out of 198; 18.2%), and ovarian (29 out of 198; 14.6%) cancer. One hundred and nineteen patients (119 out of 198, 60.1%) underwent pre-discharge TOV, of whom 14 out of 119 (11.8%) failed. Of the post-discharge TOV patients (79 out of 198, 39.9%), 5 out of 79 (6.3%) failed. The proportion of patients who failed a pre-discharge TOV was within the non-inferiority margin (5.4% difference, p = 0.23). A greater proportion of patients in the post-discharge TOV group developed long-term de novo urinary dysfunction (27.2% difference, p = 0.005). Median time to diagnosis of de novo urinary dysfunction was 0.5 years (range 0-9) in the pre-discharge TOV group versus 1.0 year (range 0-6) in the post-discharge TOV group (p > 0.05).
    CONCLUSIONS: In this study, pre-discharge TOV had non-inferior short-term outcomes and improved long-term outcomes.
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  • 文章类型: Journal Article
    背景:分娩镇痛干预,特别是使用阿片类药物和硬膜外麻醉,引起了人们对其对产后尿潴留(PUR)的潜在影响的担忧,需要对其与该临床结果的关联进行全面调查。
    方法:本回顾性病例对照研究分析了2023年1月至2023年12月我院产后患者的临床资料。麻醉方法,包括阿片类药物和非阿片类药物的使用,硬膜外镇痛和不使用镇痛,被评估。还进行了Logistic回归分析以确定与表观PUR的重要关联。
    结果:本研究包括54例有PUR的产后患者和54例无尿潴留的产后患者的临床数据。与没有PUR的妇女相比,有明显PUR的妇女在分娩期间接受阿片类药物的比例更高(p=0.033)。相反,有明显PUR的女性接受非阿片类镇痛药的比例低于无PUR的女性(p=0.026).此外,有明显PUR的女性接受硬膜外镇痛的比例高于无PUR的女性(p=0.041).Logistic回归分析表明,分娩期间阿片类药物的消耗与表观PUR显着相关(比值比(OR)=2.469,p=0.022)。相比之下,分娩期间的非阿片类药物消耗与表观PUR呈负相关(OR=0.297,95%CI=0.123-0.681,p=0.005).此外,分娩期间使用硬膜外镇痛与表观PUR显著相关(OR=2.857,95%CI=1.289-6.552,p=0.011).
    结论:分娩期间阿片类药物的使用和硬膜外镇痛的使用被认为是明显PUR的重要危险因素。这些发现强调了在分娩期间需要一种周到且平衡的镇痛管理方法,以最大程度地降低产科患者PUR的风险。
    BACKGROUND: Labor analgesic interventions, particularly the use of opioids and epidural anaesthesia, have raised concerns regarding their potential impact on postpartum urinary retention (PUR), necessitating a comprehensive investigation into their association with this clinical outcome.
    METHODS: This retrospective case-control study analysed clinical data from postpartum patients at our hospital from January 2023 to December 2023. Anaesthetic methods, including opioid and non-opioid drug usage, epidural analgesia and non-use of analgesia, were assessed. Logistic regression analysis was also performed to determine important associations with apparent PUR.
    RESULTS: This study included clinical data from 54 postpartum patients with PUR and 54 without urinary retention. A higher percentage of women with apparent PUR received opioids during labour compared with those without PUR (p = 0.033). Conversely, a lower percentage of women with apparent PUR received non-opioid analgesics compared with those without PUR (p = 0.026). In addition, a higher percentage of women with apparent PUR received epidural analgesia compared with those without PUR (p = 0.041). Logistic regression analysis demonstrated that opioid consumption during labour was significantly associated with apparent PUR (odds ratio (OR) = 2.469, p = 0.022). By contrast, non-opioid consumption during labour was inversely associated with apparent PUR (OR = 0.297, 95% CI = 0.123-0.681, p = 0.005). In addition, the use of epidural analgesia during labour showed a remarkable association with apparent PUR (OR = 2.857, 95% CI = 1.289-6.552, p = 0.011).
    CONCLUSIONS: Opioid use during labour and the use of epidural analgesia were identified as important risk factors for apparent PUR. These findings emphasise the need for a thoughtful and balanced approach to analgesic management during labour to minimise the risk of PUR in obstetric patients.
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  • 文章类型: Journal Article
    背景:术后尿潴留(POUR)是肛肠手术的常见并发症。这项研究是为了确定POUR在良性肛肠疾病的肛肠手术中的发生率,确定其风险因素,并建立POUR预测的列线图。
    方法:采用巢式病例对照研究。收集患者的临床资料,并对POUR的发生率进行了分析。单因素分析用于确定与POUR相关的危险因素,多因素logistic回归分析用于确定POUR的独立危险因素。使用逻辑回归模型开发了用于术前预测POUR的列线图(n=609)。
    结果:良性肛肠疾病肛肠手术后POUR的发生率为19.05%。POUR的独立危险因素为:女性(P=0.007);男性合并良性前列腺增生(BPH)(P=0.001);术后视觉模拟评分(VAS)评分>6(P=0.002);患者自控硬膜外镇痛(PCEA)(P=0.016);手术时间>30min(P=0.039)。在列线图中,BPH是影响POUR发生的最重要因素,术后VAS评分>6,PCEA,手术时间>30分钟,性影响最小.
    结论:对于因良性肛肠疾病而接受肛肠手术的患者,可以采取预防措施来降低POUR的风险,考虑到以下危险因素:女性或男性患有BPH,严重的术后疼痛,PCEA,手术时间>30分钟。此外,我们开发并验证了一个易于使用的列线图,用于良性肛肠疾病肛肠手术中POUR的术前预测.
    背景:中国临床试验注册:ChiCTR2000039684,2020年5月11日。
    BACKGROUND: Postoperative urinary retention (POUR) is a common complication of anorectal surgery. This study was to determine the incidence of POUR in anorectal surgery for benign anorectal diseases, identify its risk factors, and establish a nomogram for prediction of POUR.
    METHODS: A nested case-control study was conducted. The clinical data of patients were collected, and the incidence of POUR was analyzed. Univariate analysis was used to identify the risk factors associated with POUR, and multivariate logistic regression analysis was used to determine independent risk factors for POUR. A nomogram for the preoperative prediction of POUR using a logistic regression model was developed (n = 609).
    RESULTS: The incidence of POUR after anorectal surgery for benign anorectal diseases was 19.05%. The independent risk factors for POUR were: female (P = 0.007); male with benign prostatic hyperplasia (BPH) (P = 0.001); postoperative visual analogue scale (VAS) score > 6 (P = 0.002); patient-controlled epidural analgesia (PCEA) (P = 0.016); and a surgery time > 30 min (P = 0.039). In the nomogram, BPH is the most important factor affecting the occurrence of POUR, followed by a postoperative VAS score > 6, PCEA, surgery time > 30 min, and sex has the least influence.
    CONCLUSIONS: For patients undergoing anorectal surgery for benign anorectal diseases, preventive measures can be taken to reduce the risk of POUR, taking into account the following risk factors: female or male with BPH, severe postoperative pain, PCEA, and surgery time > 30 min. Furthermore, we developed and validated an easy-to-use nomogram for preoperative prediction of POUR in anorectal surgery for benign anorectal diseases.
    BACKGROUND: China Clinical Trial Registry: ChiCTR2000039684, 05/11/2020.
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    文章类型: Journal Article
    背景:剖宫产(CD)通常使用神经轴麻醉进行。使用神经轴吗啡已被证明在术后疼痛管理方面是有益的;然而,其对术后尿潴留的影响尚不清楚.
    目的:确定CD期间向神经轴注射吗啡是否会影响术后尿潴留率。
    方法:我们对接受CD的患者进行了回顾性病例对照观察研究。我们将使用鞘内或硬膜外腔注射吗啡的患者(2020年11月至2021年10月)与无吗啡的CD患者的历史队列(2019年11月至2020年10月)进行了比较。主要结果是术后明显尿潴留的发生率,需要进行膀胱导管检查。
    结果:研究组包括283名患者,对照组313例患者符合分析条件.在基线人口统计学和CD适应症方面没有发现差异。在研究组中,由于尿retention留引起的产后膀胱导尿次数较高(5%vs.1%,P值=0.003)。没有记录30天再入院的病例。此外,使用神经轴吗啡治疗的患者需要更少的术后麻醉重复剂量(口服镇痛7.4vs.10.1,静脉镇痛0.29vs.0.31,口服阿片类药物0.06vs.3.70,静脉注射阿片类药物0.01vs.0.45,全部P值<0.001)。
    结论:虽然在CD期间使用神经轴吗啡似乎是安全有效的,术后尿潴留的风险似乎由于其使用而增加。通过膀胱导管插入术治疗的明显尿潴留病例不会导致短期并发症。
    BACKGROUND: Cesarean deliveries (CD) are commonly performed using neuraxial anesthesia. The use of neuraxial morphine has proven beneficial in terms of postoperative pain management; however, its effect on postoperative urine retention remains unclear.
    OBJECTIVE: To determine whether morphine injection into the neuraxis during CD influences postoperative urinary retention rate.
    METHODS: We conducted a retrospective case-control observational study of patients undergoing CD. We compared patients using morphine injected into the intrathecal or epidural spaces (November 2020 to October 2021) to a historical cohort of patients undergoing CD without morphine (November 2019 to October 2020). The primary outcome was the rate of postoperative overt urinary retention necessitating bladder catheterization.
    RESULTS: The study group comprised 283 patients, and 313 patients in the control group were eligible for analysis. No differences were found with respect to the baseline demographic and indication for CD. The number of postpartum urinary bladder catheterizations due to urine retention was higher in the study group (5% vs. 1%, P-value = 0.003). No cases of 30-day readmission were recorded. Moreover, patients treated with neuraxial morphine required fewer repeat doses of postoperative anesthesia (oral analgesia 7.4 vs. 10.1, intravenous analgesia 0.29 vs. 0.31, oral opioids 0.06 vs. 3.70, intravenous opioids 0.01 vs. 0.45, P-value < 0.001 for all).
    CONCLUSIONS: While neuraxial morphine used during CD appears to be safe and effective, the risk of postoperative urinary retention seems to be increased due to its use. Cases of overt urinary retention treated by bladder catheterization does not lead to short-term complications.
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  • 文章类型: Journal Article
    近年来,肛周手术后剧烈疼痛严重影响住院患者的预后。如何最大限度地改善术后疼痛和围手术期舒适度就显得尤为重要。
    本研究是一项双盲随机对照试验(注册编号::ChiCTR2100048760,注册日期:2021年7月16日,链接:www。chictr.org.cn/showproj.html?proj=130226),将患者随机分为两组:一组患者术后用0.5%罗哌卡因行20mL双侧阴部神经阻滞(P组),另一组患者术后行20mL双侧阴部神经阻滞,给予0.5%罗哌卡因+8mg地塞米松(PD组).主要结果是术后第一次换药时中度至重度疼痛的发生率。次要结果包括手术后3天的恢复质量-15(QoR-15)评分,睡眠质量,术后3天疼痛评分,和不良事件的发生率。
    在主要结果指标中,P组为41.7%,PD组为24.2%(p=0.01).术前2天,PD组QoR-15评分和睡眠质量均优于P组。PD组术后尿潴留发生率明显降低(p=0.01)。
    肛周手术后地塞米松局部麻醉联合阴部神经阻滞可降低首次换药时中重度疼痛的发生率。这可能是肛周手术后多模式镇痛的方法之一。
    https://www.chictr.org.cn/,标识符ChiCTR2100048760。
    UNASSIGNED: In recent years, severe pain after perianal surgery has seriously affected the prognosis of hospitalized patients. How to maximize the improvement of postoperative pain and perioperative comfort becomes particularly important.
    UNASSIGNED: This study was a double-blind randomized controlled trial (Registration No.: ChiCTR2100048760, Registration Date: 16 July 2021, Link: www.chictr.org.cn/showproj.html?proj=130226), and patients were randomly divided into two groups: one group underwent postoperative 20 mL bilateral pudendal nerve block with 0.5% ropivacaine (P group), and the other group underwent postoperative 20 mL bilateral pudendal nerve block with 0.5% ropivacaine + 8 mg dexamethasone (PD group). The primary outcome was the incidence of moderate to severe pain at the first postoperative dressing change. Secondary outcomes included Quality of recovery-15 (QoR-15) score at 3 days after surgery, sleep quality, pain score at 3 days after surgery, and incidence of adverse events.
    UNASSIGNED: In the main outcome indicators, the incidence was 41.7% in the P group and 24.2% in the PD group (p = 0.01). The QoR-15 score and sleep quality in PD group were better than those in P group 2 days before surgery. The incidence of postoperative urinary retention was significantly decreased in PD group (p = 0.01).
    UNASSIGNED: Local anesthesia with dexamethasone combined with pudendal nerve block after perianal surgery can reduce the incidence of moderate to severe pain during the first dressing change. This may be one of the approaches to multimodal analgesia after perianal surgery.
    UNASSIGNED: https://www.chictr.org.cn/, identifier ChiCTR2100048760.
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