unusual

不寻常的
  • 文章类型: Journal Article
    在孟加拉国,自由放养的鸭养殖场为新型甲型流感病毒的产生提供了机会,这一点在2023年出现了一种不寻常的甲型(H1N1N7)病毒就证明了这一点。对具有新特性的甲型流感病毒的潜在出现的此类环境的持续监测仍然是优先事项。
    In Bangladesh, free-range duck farms provide opportunities for the generation of novel influenza A viruses as evidenced by the emergence of an unusual A(H1N7) virus in 2023. Continued surveillance of such environments for the potential emergence of influenza A viruses with novel properties remains a priority.
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  • 文章类型: Case Reports
    粘液表皮样癌(MEC)是一种通常由腮腺引起的唾液腺肿瘤。MEC有各种症状,包括无痛的,在耳叶下面或前面缓慢生长的肿块。然而,不寻常的表现也可以是耳后肿胀的形式。耳后肿胀的其他更常见的良性差异包括淋巴结病,表皮样囊肿,还有脂肪瘤.因此,仅根据临床表现将耳廓后肿胀诊断为MEC具有挑战性,高度怀疑,以及具有各种放射学研究的多学科方法,例如计算机断层扫描(CT)和磁共振成像(MRI),需要与组织病理学评估合作才能准确诊断这种恶性肿瘤。预后取决于各种因素,包括肿瘤的分级,病人的年龄,和合并症,以及诊断时的阶段。早期诊断和手术干预是治疗的支柱,之后可以根据恶性肿瘤的分期进行辅助放疗。这是一个患者出现耳后肿胀的报告,最初被误诊为良性坏死淋巴结。经过进一步评估,它被发现是腮腺粘液表皮样癌,通过手术切除和放射治疗。
    Mucoepidermoid carcinoma (MEC) is a salivary gland tumor commonly arising from the parotid gland. MEC has various presenting symptoms, including a painless, slow-growing mass below or anterior to the ear lobule. However, an unusual presentation can also be in the form of post-auricular swelling. Other more common benign differentials for post-auricular swelling include lymphadenopathy, epidermoid cysts, and lipomas. Thus, diagnosing a postauricular swelling as MEC solely based on clinical presentation is challenging, and a high suspicion, as well as a multidisciplinary approach with various radiological investigations such as computed tomography (CT) and magnetic resonance imaging (MRI), are required in collaboration with histopathological assessment for an accurate diagnosis of this malignancy. Prognosis depends on various factors, including the grade of the tumor, the patient\'s age, and comorbidities, as well as the stage at the time of diagnosis. Early diagnosis and surgical intervention are the mainstays of treatment, which can be followed by adjuvant radiotherapy based on the stage of the malignancy. This is a report of a patient who presented with post-auricular swelling, which was initially misdiagnosed as a benign necrotic lymph node. After further evaluation, it was found to be a mucoepidermoid carcinoma of the parotid gland, which was managed by surgical excision and radiotherapy.
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  • 文章类型: Journal Article
    The coeliac trunk, the first anterior branch, often originates at the level of the T12 vertebral body, right below the aortic hiatus, as the first ventral branch of the abdominal aorta. It commonly divides into the left gastric, common hepatic, and splenic arteries. We report a rare variation in the branching pattern and course of branches of the coeliac trunk in two donated female cadavers during routine abdominal dissection. It is essential to understand the coeliac trunk and the distinctions in its origin and branching pattern to perform efficient upper abdominal surgical and radiological procedures and to adopt novel interventional and treatment options for hepatic cancers. As anatomists, we are also attempting to link our study\'s variations to their embryological genesis.
    İlk ön dal olan çölyak trunkus, abdominal aortanın ilk ventral dalı olarak genellikle T12 vertebral cisim seviyesinde, aortik hiatusun hemen altından çıkar. Genellikle sol gastrik, ortak hepatik ve splenik arterlere ayrılır. Bu yazıda, bağışlanan iki kadın kadavrada, rutin abdominal diseksiyon sırasında çölyak trunkusun dallanma paterninde ve seyrinde görülen nadir bir varyasyon sunulmaktadır. Etkin üst abdominal cerrahi ve radyolojik prosedürler gerçekleştirmek ve karaciğer kanserleri için yeni girişimsel ve tedavi seçeneklerini benimsemek için çölyak trunkusu ve kökenindeki ve dallanma paternindeki farklılıkları anlamak çok önemlidir. Anatomi uzmanları olarak biz de çalışmamızdaki varyasyonları embriyolojik oluşumlarıyla ilişkilendirmeye çalışmaktayız.
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  • 文章类型: Journal Article
    我们研究的目的是报告患者的毛霉菌病的异常表现,他们从COVID-19感染中恢复过来。这是一项前瞻性观察研究,在拉文德拉·纳特·泰戈尔医学院进行,乌代布尔,印度,过去3个月(2021年4月至6月)。所有颌面部和牙齿毛霉菌病患者均纳入研究。所有患者要么患有COVID-19感染,要么从中康复。8例(40%)患者有使用皮质类固醇治疗COVID1-19感染的病史,15名患者有已知的糖尿病病例或新诊断的糖尿病患者在就诊时血糖不受控制,3例(15%)患者处于糖尿病前期状态,HbA1c在6.0%~6.5%之间,2例患者无糖尿病.没有患者患有糖尿病酮症酸中毒,只有一名患者报告视力完全丧失并伴有牙齿症状。在不受控制的糖尿病中,毛霉菌病以牙齿松动的形式出现。不当使用类固醇和不受控制的糖尿病是两个主要的危险因素,所以眼睛应该保持在这两个。
    Aim of our study was to report unusual presentation of mucormycosis in patients, who were recovered from COVID-19 infection. This was a prospective observational study, undertaken at Ravindra Nath Tagore Medical College, Udaipur, India, over a period of last 3 months (April-June 2021). All patients with maxillofacial and dental mucormycosis were included in the study. All patients either have COVID-19 infection or recovered from it. Eight (40%) patients had history of use of corticosteroids for COVID1-19 infection, fifteen patients had either known case of diabetes or newly diagnosed diabetes with uncontrolled blood sugar at the time of presentation, three (15%) patients were in pre-diabetic state with HbA1c between 6.0 and 6.5% and two patients had no diabetes. None of patients had diabetic ketoacidosis and only one patient reported complete loss of vision with dental symptoms. There was unusual presentation of mucormycosis in form of loosening of teeth in uncontrolled diabetes. Injudicious use of steroids and uncontrolled diabetes are two main risk factors, so eyes should be kept on both of these.
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  • 文章类型: Journal Article
    合成反铁磁体(SAF)是一种出色的系统,可通过调整层厚度和材料成分来控制磁耦合。这里,我们控制垂直磁化SAFPt/Co/Ir/CoFeB/MgO多层膜中的层间交换耦合(IEC),通过改变非磁性层Ir厚度和磁性层Co厚度来调节。并且我们研究了自旋轨道转矩(SOT)驱动的SAF磁化切换。在IEC较弱的SAF中,SOT驱动的开关行为类似于单个铁磁体系统,由外部磁场主导。相比之下,在拥有超强IEC的SAF中,饱和磁场大于50kOe,SOT驱动的开关行为由有效磁场决定。有效磁场与外部磁场相关,IEC领域,CoFeB和Co的磁矩,和磁各向异性。这些结果可以促进对垂直SAF的SOT切换的理解,并促进具有低杂散场和较低功率的SAF在自旋电子器件中的应用。
    Synthetic antiferromagnet (SAF) is an outstanding system for controlling magnetic coupling via tuning the layer thickness and material composition. Here, we control the interlayer exchange coupling (IEC) in a perpendicularly magnetized SAF Pt/Co/Ir/CoFeB/MgO multilayer, which is tuned by varying the nonmagnetic layer Ir thickness and the magnetic layer Co thickness. And we study the spin-orbit torque (SOT) driven magnetization switching of the SAF. In the SAF with a weak IEC, the SOT-driven switching behavior is similar to that of a single ferromagnet system, which is dominated by the external magnetic field. In contrast, in the SAF with an ultra-strong IEC, the saturation magnetic field is large than 50 kOe, and the SOT-driven switching behavior is decided by the effective magnetic field. The effective field is correlated to the external magnetic field, the IEC field, magnetic moments of CoFeB and Co, and magnetic anisotropy. These results may advance the understanding of SOT switching of perpendicular SAFs and promote the applications of SAFs with low stray fields and lower power in spintronic devices.
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  • 文章类型: Journal Article
    传统上,麻风病已分为从结核菌到麻风病极的各种光谱,以及组织,纯神经炎麻风病和反应状态。然而,这是过度简化,因为麻风病可能以异常的临床形式出现,可能会混淆诊断。我们的目标是强调麻风病在所有疾病谱中发生的异常临床表现。我们的病例系列描述了2011年至2021年10年间发现的八种罕见的麻风病表现,其中进行了临床诊断,然后进行了麻风病的组织病理学确认。这些包括罕见的表现,如银屑病样斑块,拉扎林麻风病,疣状斑块和肥厚性瘢痕。这些罕见的演讲中的许多至今仍未报道,如原发性性腺功能减退症和环状斑块模仿环带性红斑离心和旋回性红斑。结节病和梅毒在皮肤病学中被标记为伟大的模仿者。当前的病例系列和审查是试图强调许多麻风病的不寻常表现,需要单独提及才能做出正确和及时的诊断,并防止这种本来可以治疗的传染病的衰弱后遗症。
    Conventionally, leprosy has been divided into various spectra of presentation ranging from the tuberculoid to the lepromatous pole, as well as histoid, pure neuritic leprosy and reactional states. This however is an oversimplification as leprosy can present in unusual clinical forms that may obfuscate the diagnosis. Our objective was to highlight unusual clinical presentations of leprosy occurring across all spectra of the disease. Our case series describes eight uncommon presentations of leprosy seen over a period of 10 y from 2011 to 2021, wherein clinical diagnosis followed by a histopathological confirmation of leprosy was performed. These include rare presentations such as psoriasiform plaques, Lazarine leprosy, verrucous plaques and hypertrophic scarring. Many of these rare presentations remain hitherto unreported, such as primary hypogonadism and annular plaques mimicking erythema annulare centrifugum and erythema gyratum repens. Sarcoidosis and syphilis have been labeled as great mimickers in dermatology. The current case series and review is an attempt to highlight a multitude of unusual presentations of leprosy that need a separate mention to make a correct and timely diagnosis and prevent the debilitating sequelae of this otherwise treatable infectious disease.
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  • 文章类型: Journal Article
    未经证实:尽管在COVID19中已经报道了一些外周血异常,但白红母细胞病是一个不寻常的发现。我们报告了33例表现为白细胞红细胞增多症的COVID19病例。我们打算描述其在这种新型病毒感染中的发生率,并将其与临床结果相关联。
    未经证实:这是一项在LUCKNOWCOVID19三级医院进行的前瞻性研究,印度回顾了2020年8月20日至2020年9月30日收治的COVID19例患者入院第一天的血液学检查记录。对标记为异常的测试结果进行外周血涂片检查。当涂片显示存在粒细胞左移和有核红细胞时,报告了白红细胞增多症。在第7天检查后续涂片。这些发现与临床结果相关。
    UNASSIGNED:在查看的274张幻灯片中,33(12%)在入院第1天显示出白细胞成红细胞图。在第7天的随访涂片在76%(25/33)的病例中可用。随访涂片显示13例好转,恶化9例,无变化3例。共有19人(58%)死亡。12名患者(36%)康复,2名患者(6%)被转移到其他无法进一步随访的医院。
    未经授权:白红母细胞病是COVID19的一种不寻常表现。虽然罕见,这种外周血异常可以深入了解潜在的病理生理过程.此外,这似乎是一个不利的预后因素,因此,对随访涂片的检查可能有助于临床医生和重症医师迅速做出管理决策。
    UNASSIGNED: Although several peripheral blood abnormalities have been reported in COVID 19,Leukoerythroblastosis is an unusual finding. We report 33 COVID19 cases presenting with leukoerythroblastosis. We intend to describe its incidence in this novel viral infection and correlate it with the clinical outcome.
    UNASSIGNED: It is a Prospective study done at a Level 3 COVID 19 hospital of LUCKNOW, INDIA. Hematologic test records of day 1 of admission of COVID 19 cases admitted from 20th August 2020 to 30th September 2020 were reviewed. Peripheral blood smear examination was performed on test results that were flagged for abnormalities. Leukoerythroblastosis was reported when the smears showed presence of granulocyte left shift and nucleated red blood cells. Follow up smears were examined on Day 7. The findings were correlated with the clinical outcome.
    UNASSIGNED: Out of 274 slides reviewed, 33 (12%) showed a leukoerythroblastic picture on day 1 of admission. Follow up smears on day 7 were available in 76% (25/33) cases. The follow up smears showed improvement in 13 cases, worsening in 9 cases and no changes in 3 cases. There were total 19 (58%) deaths. 12 patients (36%) recovered and 2 patients (6%) were shifted to other hospitals whose further follow up was not available.
    UNASSIGNED: Leukoerythroblastosis is an unusual presentation of COVID 19. Although rare, this peripheral blood abnormality can provide insight into the underlying pathophysiologic processes. Furthermore, it seems to be an adverse prognostic factor, so examination of follow up smears may help clinicians and intensivists to make prompt management decisions.
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  • 文章类型: Journal Article
    UNASSIGNED: Adrenal myelolipomas are rare, benign tumours with an incidence of 0.08-0.2%. They present between the fifth and seventh decade of life [1].
    METHODS: Our patient presented with complaints of vomiting and left lumbar pain of four weeks duration. Blood work revealed dyselectrolytemia. Contrast enhanced computed tomography of the abdomen and pelvis confirmed the diagnosis and the patient was planned for an adrenalectomy. Histopathology report revealed the pathology. She is currently on routine follow up and is disease free. Written informed consent was obtained from the patient for publication of this case report and its accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal on request. This case report has been reported in line with the SCARE criteria [2].
    UNASSIGNED: With the increased use of imaging modalities of the abdomen, they are now considered to be the second most common cause of adrenal incidentalomas (6-16%) [3]. Most tumours are small, asymptomatic and often go undiagnosed. Large tumours can cause chronic pain and other nonspecific symptoms.
    CONCLUSIONS: Though myelolipomas are identified on routine CT scans, on a background of dyselectrolytemia, a further evaluation is of utmost importance to rule out the possibility of a functioning tumour.
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  • 文章类型: Journal Article
    多年来,胸腺瘤的命名法一直在争论这些肿瘤的最佳分组方式。在迄今为止呈现的每个模式中,主要问题是淋巴细胞的存在或缺乏,肿瘤已被归入特定类别。然而,尽管这个概念适用于大多数情况,有许多肿瘤不一定属于这些类别,因为胸腺瘤显示与上皮细胞相关的另一种细胞增殖,或者上皮细胞本身的排列模式与经典胸腺瘤的常规特征不同。在这里,我们将强调这些功能,在某些情况下,主要是纵隔镜下的小活检可能会在解释中造成相当大的问题。我们确实认为最重要的问题是熟悉这些肿瘤可能表现出的不同生长模式,以避免误诊。此外,我们认为,无论肿瘤的生长模式或细胞组成如何,强烈建议像其他肿瘤一样仔细取样并正确分期。尽管我们充分意识到胸腺瘤可能表现出的不同的生长模式和特定的细胞细节,对每一种肿瘤的讨论超出了本综述的范围.因此,我们更加强调这些,在我们的判断中,这在日常实践中更常见。
    Over the years the nomenclature of thymomas has been debated regarding the best manner in which these tumors should be grouped. In every schema presented thus far, the main issue has been the presence or lack of lymphocytes and accordingly, the tumors have been place into a specific category. However, even though this concept applies for most of the cases, there are numerous tumors that do not necessarily fit into those categories as either the thymomas show another cellular proliferation associated with the epithelial cells or the epithelial cell themselves are arranged in a pattern that departs from the conventional features of the classic thymoma. Herein we will emphasize those features, which in some circumstances, mainly with small mediastinoscopic biopsies may pose a considerable problem in interpretation. We do consider that the most important issue is to be familiar with the different growth pattern that these tumors may show in order to avoid misdiagnosis. In addition, we consider that regardless of the growth pattern or cellular composition of the tumor, it is highly recommended that these tumors just like any other be carefully sampled and properly stage. Although we are fully aware of the different growth pattern and specific cellular details that thymoma may show, the discussion of each one of those tumors is beyond the scope of this review. Therefore, we have placed more emphasis in those, which in our judgment are more commonly encountered in the daily practice.
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  • 文章类型: Journal Article
    肠结石或胃肠道结石的形成是一种罕见的医学病症,由于各种病理而在肠淤滞的背景下发展。其患病率高达10%,可以在不同的临床图片中呈现,以挑战临床医生。
    Enterolithiasis or formation of gastrointestinal concretions is an uncommon medical condition that develops in the setting of intestinal stasis due to various pathologies. Its prevalence ranges upto 10% and can present in different clinical pictures to challenge a clinician.
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