■轴性脊柱关节炎(axSpA)包括胸部表现和呼吸功能变化,需要全面了解才能有效治疗。这篇综述旨在研究这些表现,并评估超声在检测膈肌改变中的作用,为axSpA患者的改进诊断和治疗策略提供见解。
■从2003年至2023年在IndexMedicus和Scopus中进行了系统搜索。纳入标准包括主要和次要出版物,重点是高质量的证据,如随机对照试验和有或没有荟萃分析的系统评价。关键词脊柱关节炎,呼吸,胸部,胸廓,在搜索中使用了隔膜和超声。重复后共鉴定出22篇文章,和不充分的文件被删除。
■审查包括患病率,axSpA的分类和关节外表现,强调对呼吸功能的影响。胸部表现和药物干预的潜在影响进行了详细的研究,并讨论了影响呼吸动力学的各种条件。此外,解释了超声检查在评估膈肌功能中的应用,用于评估膈肌运动的参数和测量,描述了肌肉厚度和呼吸流动性。结果表明axSpA患者膈肌功能的变化及其与疾病活动的相关性。
■这篇叙述性综述强调了axSpA与呼吸表现之间的复杂关系,并强调了对胸功能和膈肌动力学的重大影响。超声在评估膈肌功能中的应用为客观评估提供了一个有希望的途径,该途径提供了对疾病活动和潜在治疗反应的见解。这篇综述强调了早期诊断和警惕监测的关键作用。并倡导采用多学科方法,整合非药物干预措施,特别是量身定制的身体活动,以维持和改善axSpA患者的呼吸功能。增加研究计划和对axSpA肺部并发症的认识对于优化该患者组的医疗保健和改善治疗结果至关重要。
UNASSIGNED: Axial spondyloarthritis (axSpA) includes thoracic manifestations and changes in respiratory function that require a comprehensive understanding for effective treatment. This
review aims to investigate these manifestations and evaluate the role of ultrasound in detecting diaphragmatic changes to provide insights for improved diagnosis and treatment strategies in axSpA patients.
UNASSIGNED: A systematic search was conducted in Index Medicus and Scopus from 2003 to 2023. Inclusion criteria included primary and secondary publications, with a focus on high-quality evidence such as randomised controlled trials and systematic reviews with or without meta-analysis. Keywords spondyloarthritis, respiratory, chest, thoracic, diaphragm and ultrasound were used in the search. A total of 22 articles were identified after duplicates, and inadequate papers were removed.
UNASSIGNED: The
review included the prevalence, classification and extra-articular manifestations of axSpA, highlighting the impact on respiratory function. Thoracic manifestations and the potential impact of pharmacological interventions were detailed, and various conditions affecting respiratory dynamics were discussed. In addition, the utility of
ultrasonography in assessing diaphragmatic function was explained and the techniques, parameters and measurements used to assess diaphragmatic movement, muscle thickness and respiratory mobility were described. The results illustrate the changes in diaphragmatic function in axSpA patients and their correlation with disease activity.
UNASSIGNED: This narrative
review highlights the intricate relationship between axSpA and respiratory manifestations and emphasises the significant impact on thoracic function and diaphragmatic dynamics. The utility of ultrasound in assessing diaphragmatic function offers a promising avenue for objective evaluation that provides insight into disease activity and potential therapeutic responses. This
review emphasises the critical role of early diagnosis and vigilant monitoring, and advocates a multidisciplinary approach that integrates non-pharmacological interventions, particularly tailored physical activity, to maintain and improve respiratory function in axSpA patients. Increased research initiatives and awareness of pulmonary complications in axSpA are essential to optimise medical care and improve treatment outcomes in this patient group.