Abstract：
Toxocariasis, a zoonotic infection transmitted by Toxocara canis (from dogs) and Toxocara cati (from cats) larvae, poses rare but severe risks to humans. We present a case of hepatic visceral larva migrans (VLM) caused by Toxocara canis in a 21-year-old male with a history of close contact with a pet dog. Initial symptoms and imaging findings mimicked a pyogenic liver abscess. The initial laboratory investigations revealed neutrophilia and elevated levels of IgE. Despite broad-spectrum antibiotics, persistent fever prompted further investigation. Subsequent serological testing for Toxocara antibodies and histopathological analysis of liver tissue demonstrating eosinophil infiltrates and Charcot-Leyden crystals led to a confirmed diagnosis of a liver abscess caused by Toxocara canis. Serological testing for Toxocara antibodies and histopathological analysis of liver tissue confirmed a Toxocara canis-induced liver abscess. Albendazole treatment yielded significant clinical improvement. This case highlights the necessity of considering toxocariasis in liver abscess differentials, particularly in high-seroprevalence regions like Vietnam. Relying solely on serological tests may be insufficient, emphasizing the need for corroborative evidence, including invasive procedures like liver biopsy, for accurate hepatic toxocariasis diagnosis.
摘要：
弓形虫病,由犬弓形虫（来自狗）和弓形虫（来自猫）幼虫传播的人畜共患感染，对人类构成罕见但严重的风险。我们介绍了一例由犬弓形虫引起的肝内脏幼虫（VLM）病例，该病例有与宠物狗密切接触的病史。最初的症状和影像学表现模仿化脓性肝脓肿。最初的实验室调查显示嗜中性粒细胞增多和IgE水平升高。尽管有广谱抗生素,持续发烧促使进一步调查。随后对Toxocara抗体进行血清学测试，并对肝组织进行组织病理学分析，证明嗜酸性粒细胞浸润和Charcot-Leyden晶体可明确诊断为犬弓形虫引起的肝脓肿。弓形虫抗体的血清学测试和肝组织的组织病理学分析证实了弓形虫诱发的肝脓肿。阿苯达唑治疗产生了显著的临床改善。该病例强调了在肝脓肿差异中考虑弓形虫病的必要性，特别是在像越南这样的高血清阳性率地区。仅仅依靠血清学检测可能是不够的,强调需要确凿证据，包括肝活检等侵入性手术，用于准确的肝弓形虫病诊断。
