transitional cell carcinoma

移行细胞癌
  • 文章类型: Journal Article
    这项研究的目的是确定接受CT尿路造影(CTU)的无症状镜下血尿患者是否符合美国泌尿外科协会的放射学评估标准,并确定CTU对上呼吸道恶性肿瘤的产量。
    对成人患者无症状镜下血尿的连续CTU检查进行回顾性分析。有临床证据提示良性血尿的患者(结石,尿路感染,外伤)或先前的泌尿系恶性肿瘤被排除在外。研究组包括419名患者(173名男性,246名妇女)。对CT报告进行审查,以确定所有病例中血尿的原因。对200名随机分配的患者进行了适当性评估。对尿液分析结果进行了综述,CTU的适当使用定义为在没有尿路感染的情况下,每个高倍视野超过3个红细胞。记录CTU后的膀胱镜检查结果。
    总共,200例患者中有58例(29.0%;95%CI,23.2-35.6%)不符合美国泌尿外科协会的放射学评估标准。15(7.5%)只接受试纸分析。38例(19.0%)的尿液分析结果显示每个高功率场0-2个RBC。发现五名患者(2.5%)患有尿路感染。未发现上尿路上皮肿瘤(0/419;95%CI,0.0-0.9%)。鉴定出一个实性肾肿块,无病理证实。在CTU观察到一种可能的膀胱肿块,但在随后的膀胱镜检查中未发现。
    在29.0%的考试中,CTU适用于不符合放射学评估标准的患者。CTU用于上尿路恶性肿瘤的产量低。
    The purposes of this study were to determine whether patients with asymptomatic microscopic hematuria undergoing CT urography (CTU) meet the American Urological Association criteria for radiologic evaluation and to determine the yield of CTU for upper tract malignancy.
    A retrospective review was conducted of consecutive CTU examinations performed for asymptomatic microscopic hematuria in adult patients. Patients with clinical evidence suggestive of a benign cause of hematuria (stone, urinary tract infection, trauma) or prior urologic malignancy were excluded. The study group included 419 patients (173 men, 246 women). CT reports were reviewed to identify causes of hematuria in all cases. Evaluate for appropriateness was conducted with 200 randomly allocated patients. Urinalysis results were reviewed, and appropriate use of CTU was defined as more than 3 RBCs per high-power field in the absence of urinary tract infection. Cystoscopy results after CTU were noted.
    In total, 58 of 200 patients (29.0%; 95% CI, 23.2-35.6%) did not meet American Urological Association criteria for radiologic evaluation. Fifteen (7.5%) received dipstick analysis only. Thirty-eight (19.0%) had urinalysis results showing 0-2 RBCs per high-power field. Five patients (2.5%) were found to have urinary tract infections. No upper tract urothelial neoplasms were identified (0/419; 95% CI, 0.0-0.9%). One solid renal mass was identified without pathologic confirmation. One possible bladder mass was seen at CTU but not visualized at subsequent cystoscopy.
    In 29.0% of examinations, CTU is performed for patients who do not meet the criteria for radiologic evaluation. The yield of CTU for upper urinary tract malignancy is low.
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  • 文章类型: Journal Article
    目的:制定旨在表征肾脏肿块的磁共振成像技术指南(多参数磁共振成像,MPMRI)和膀胱和上尿路成像(磁共振尿路造影,MRU)。
    方法:法国泌尿生殖系统成像学会组织了一次德尔菲共识会议,进行了两轮德尔菲调查,然后进行了面对面的会议。针对肾脏mpMRI和MRU发布了两份单独的问卷。共识是使用先验标准严格定义的。
    结果:42位专业的太阳放射学家完成了两轮调查,两轮调查之间没有任何损耗。mpMRI问卷的84个陈述中的56个(67%)和MRU问卷的44/71个陈述中的56个(62%)达成了最终共识。对于MPMRI,人们一致认为不需要注射呋塞米,成像方案应包括T2加权成像,双重化学位移成像,弥散加权成像(使用多个b值;最大b值,1000s/mm2)和脂肪饱和单推注多相(未增强,皮质髓质,肾图)对比增强成像;晚期成像(注射后10分钟以上)被认为是可选的。对于MRU,患者应在检查前排空膀胱。协议必须包括T2加权成像,解剖快速T1/T2加权成像,弥散加权成像(使用多个b值;最大b值,1000s/mm2)和脂肪饱和单推注多相(未增强,皮质髓质,肾图,排泄)对比增强成像。在注射造影剂之前,必须静脉注射呋塞米。重度T2加权胰胆管造影术样成像被认为是可选的。
    结论:本次以专家为基础的共识会议为规范肾脏磁共振成像提供了建议,输尿管和膀胱。
    结论:•多参数磁共振成像(mpMRI)旨在表征肾脏肿块;磁共振尿路造影(MRU)旨在对膀胱和收集系统进行成像。•对于mpMRI,不需要注射呋塞米。•对于MRU,在注射造影剂前必须静脉注射呋塞米;大量T2加权胰胆管造影样成像是可选的.
    OBJECTIVE: To develop technical guidelines for magnetic resonance imaging aimed at characterising renal masses (multiparametric magnetic resonance imaging, mpMRI) and at imaging the bladder and upper urinary tract (magnetic resonance urography, MRU).
    METHODS: The French Society of Genitourinary Imaging organised a Delphi consensus conference with a two-round Delphi survey followed by a face-to-face meeting. Two separate questionnaires were issued for renal mpMRI and for MRU. Consensus was strictly defined using a priori criteria.
    RESULTS: Forty-two expert uroradiologists completed both survey rounds with no attrition between the rounds. Fifty-six of 84 (67%) statements of the mpMRI questionnaire and 44/71 (62%) statements of the MRU questionnaire reached final consensus. For mpMRI, there was consensus that no injection of furosemide was needed and that the imaging protocol should include T2-weighted imaging, dual chemical shift imaging, diffusion-weighted imaging (use of multiple b-values; maximal b-value, 1000 s/mm2) and fat-saturated single-bolus multiphase (unenhanced, corticomedullary, nephrographic) contrast-enhanced imaging; late imaging (more than 10 min after injection) was judged optional. For MRU, the patients should void their bladder before the examination. The protocol must include T2-weighted imaging, anatomical fast T1/T2-weighted imaging, diffusion-weighted imaging (use of multiple b-values; maximal b-value, 1000 s/mm2) and fat-saturated single-bolus multiphase (unenhanced, corticomedullary, nephrographic, excretory) contrast-enhanced imaging. An intravenous injection of furosemide is mandatory before the injection of contrast medium. Heavily T2-weighted cholangiopancreatography-like imaging was judged optional.
    CONCLUSIONS: This expert-based consensus conference provides recommendations to standardise magnetic resonance imaging of kidneys, ureter and bladder.
    CONCLUSIONS: • Multiparametric magnetic resonance imaging (mpMRI) aims at characterising renal masses; magnetic resonance urography (MRU) aims at imaging the urinary bladder and the collecting systems. • For mpMRI, no injection of furosemide is needed. • For MRU, an intravenous injection of furosemide is mandatory before the injection of contrast medium; heavily T2-weighted cholangiopancreatography-like imaging is optional.
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