使用光学泵浦磁力计的可穿戴脑磁图的应用在神经科学领域引起了广泛关注。脑电图系统可以覆盖整个头部,并反映大量神经元的整体活动。可以通过脑电图结果来验证光泵浦磁力计在检测事件相关分量中的功效。多变量模式分析能够跟踪神经认知过程随时间的演变。在本文中,我们采用了经典的中文语义一致性范式,并分别收集了脑电图和光泵浦磁力计信号。然后,我们验证了光泵浦磁力计和脑电图在使用互信息指数检测N400中的一致性。多元模式分析揭示了这两种模式的解码性能差异,这可以通过对时间泛化矩阵的动态/稳定编码分析进一步验证。探照灯分析的结果为脑磁图源水平和脑电图传感器水平的这种差异提供了神经基础。这项研究为使用可穿戴脑磁图研究大脑的编码模式开辟了一条新途径,并揭示了两种模式在反映神经元表示模式方面的敏感性差异。
The application of wearable magnetoencephalography using optically-pumped magnetometers has drawn extensive attention in the field of neuroscience. Electroencephalogram system can cover the whole head and reflect the overall activity of a large number of neurons. The efficacy of optically-pumped magnetometer in detecting event-related components can be validated through electroencephalogram results. Multivariate pattern analysis is capable of tracking the evolution of neurocognitive processes over time. In this paper, we adopted a classical Chinese semantic congruity paradigm and separately collected electroencephalogram and optically-pumped magnetometer signals. Then, we verified the consistency of optically-pumped magnetometer and electroencephalogram in detecting N400 using mutual information index. Multivariate pattern analysis revealed the difference in decoding performance of these two modalities, which can be further validated by dynamic/stable coding analysis on the temporal generalization matrix. The results from searchlight analysis provided a neural basis for this dissimilarity at the magnetoencephalography source level and the electroencephalogram sensor level. This
study opens a new avenue for investigating the brain\'s coding patterns using wearable magnetoencephalography and reveals the differences in sensitivity between the two modalities in reflecting neuron representation patterns.