term birth

足月出生
  • 文章类型: Journal Article
    评估孕妇在怀孕期间的饮食摄入量以及对2020-2025年美国人妊娠特定饮食指南(DGA)的遵守情况。
    这是一项回顾性观察性研究。研究人群包括分娩足月婴儿(妊娠>37周)的妇女。参与者在出生后接受了饮食筛查问卷(DSQ),并要求他们回忆怀孕最后一个月的饮食摄入量。然后将参与者的估计饮食摄入量与2020-2025年DGA进行比较,其中包括针对孕妇的具体建议。
    在完成DSQ的51名女性中,没有人摄入所有调查饮食因素的推荐量.具体来说,只有一名女性(2%)达到建议的水果摄入量,11名女性(22%)达到建议的钙摄入量,25名女性(49%)超过了建议的添加糖摄入量上限,没有一个女性(0%)满足蔬菜的摄入量,全谷物,乳制品和纤维。
    我们研究中的女性在妊娠最后一个月没有遵守妊娠特异性DGA建议。我们的发现强调了提高孕产妇营养意识和教育以提高对DGA的依从性的必要性。
    UNASSIGNED: To assess maternal dietary intake during pregnancy and adherence to the 2020-2025 pregnancy-specific Dietary Guidelines for Americans (DGA).
    UNASSIGNED: This was a retrospective observational study. The study population consisted of women who gave birth to term infants (>37 weeks of gestation). Participants were given the Dietary Screener Questionnaire (DSQ) after birth and asked to recall their dietary intake in the last month of pregnancy. Participants\' estimated dietary intakes were then compared to the 2020-2025 DGA which includes specific recommendations for pregnant women.
    UNASSIGNED: Out of 51 women who completed the DSQ, none consumed the recommended amounts of all surveyed dietary factors. Specifically, only one woman (2%) met the recommended intake of fruits, 11 women (22%) met the recommended intake of calcium, 25 women (49%) exceeded the recommended upper limit for added sugar intake, and none of the women (0%) met the intake of vegetables, whole grains, dairy and fiber.
    UNASSIGNED: Women in our study did not adhere to the pregnancy-specific DGA recommendations in the last month of pregnancy. Our findings underscore the need to increase maternal nutritional awareness and education to improve adherence to the DGA.
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  • 文章类型: Journal Article
    评估单胎和双胎妊娠中延迟(延迟)脐带夹紧(DCC)和脐带挤奶对母婴死亡率和发病率的影响。
    怀孕早产或足月单身或双胞胎的女性。
    在早产儿中,DCC(理想情况下)60到120秒,但至少30秒,降低婴儿死亡率和发病率的风险。早产双胞胎的DCC与一些益处相关。在单身人士中,DCC持续60秒改善血液学参数。在非常早产儿中,脐带挤奶增加脑室内出血的风险。
    搜索Medline,PubMed,Embase,从成立到2020年3月,Cochrane图书馆使用医学主题标题(MeSH)术语和与延迟脐带夹紧和脐带挤奶相关的关键词进行。本文件是对证据的抽象,而不是方法学审查。
    作者使用建议等级评估对证据质量和建议强度进行了评估,开发和评估(等级)方法。见在线附录A(表A1的定义和A2的强和条件[弱]建议的解释)。
    UNASSIGNED: To assess the impact of deferred (delayed) cord clamping (DCC) and umbilical cord milking in singleton and twin gestations on maternal and infant mortality and morbidity.
    UNASSIGNED: Women who are pregnant with preterm or term singletons or twins.
    UNASSIGNED: In preterm singletons, DCC for (ideally) 60 to 120 seconds, but at least for 30 seconds, reduces infant risk of mortality and morbidity. DCC in preterm twins is associated with some benefits. In term singletons, DCC for 60 seconds improves hematological parameters. In very preterm infants, umbilical cord milking increases risk for intraventricular hemorrhage.
    UNASSIGNED: Searches of Medline, PubMed, Embase, and the Cochrane Library from inception to March 2020 were undertaken using Medical Subject Heading (MeSH) terms and key words related to deferred cord clamping and umbilical cord milking. This document represents an abstraction of the evidence rather than a methodological review.
    UNASSIGNED: The authors rated the quality of evidence and strength of recommendations using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. See online Appendix A (Tables A1 for definitions and A2 for interpretations of strong and conditional [weak] recommendations).
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  • 文章类型: Practice Guideline
    目的:评估单胎和双胎妊娠延迟(延迟)脐带夹闭(DCC)和脐带挤奶对母婴死亡率和发病率的影响。
    方法:孕妇有早产或足月的单胎或双胎。
    结果:在早产儿中,DCC(理想情况下)60到120秒,但至少30秒,降低婴儿死亡率和发病率的风险。早产双胞胎的DCC与一些益处相关。在单身人士中,DCC持续60秒改善血液学参数。在非常早产儿中,脐带挤奶增加脑室内出血的风险。
    方法:搜索Medline,PubMed,Embase,从成立到2020年3月,Cochrane图书馆使用医学主题标题(MeSH)术语和与延迟脐带夹紧和脐带挤奶相关的关键词进行。本文件是对证据的抽象,而不是方法学审查。
    方法:作者使用建议分级评估对证据质量和建议强度进行了评估,开发和评估(等级)方法。见在线附录A(表A1的定义和A2的强和条件[弱]建议的解释)。
    未经评估:产妇和新生儿护理提供者。
    结论:
    OBJECTIVE: To assess the impact of deferred (delayed) cord clamping (DCC) and umbilical cord milking in singleton and twin gestations on maternal and infant mortality and morbidity.
    METHODS: People who are pregnant with preterm or term singletons or twins.
    RESULTS: In preterm singletons, DCC for (ideally) 60 to 120 seconds, but at least for 30 seconds, reduces infant risk of mortality and morbidity. DCC in preterm twins is associated with some benefits. In term singletons, DCC for 60 seconds improves hematological parameters. In very preterm infants, umbilical cord milking increases risk for intraventricular hemorrhage.
    METHODS: Searches of Medline, PubMed, Embase, and the Cochrane Library from inception to March 2020 were undertaken using Medical Subject Heading (MeSH) terms and key words related to deferred cord clamping and umbilical cord milking. This document represents an abstraction of the evidence rather than a methodological review.
    METHODS: The authors rated the quality of evidence and strength of recommendations using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. See online Appendix A (Tables A1 for definitions and A2 for interpretations of strong and conditional [weak] recommendations).
    UNASSIGNED: Maternity and newborn care providers.
    CONCLUSIONS:
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  • 文章类型: Evaluation Study
    为了评估新生儿复苏计划的关联,第7版对胎粪污染羊水(MSAF)出生的足月婴儿的变化。
    我们评估了复苏团队从2014年1月1日至2017年6月30日看到的14322名MSAF出生的无活力足月婴儿不再常规插管的效果,城市,学术医院。
    改变指南后,MSAF足月婴儿的产房插管率从19%下降到3%(P=<.0001)。所有其他产房插管的比率也下降了3%。第七版指南实施后,1分钟Apgar评分显著更可能>3(P=.009),显著更不可能<7(P=.011)。生命第一天后对持续呼吸支持的需求也减少了。NICU的入院率,逗留时间,入院时呼吸支持的需求没有变化。
    新生儿复苏计划的实施,第七版针对MSAF出生的常规吸痰不剧烈婴儿的建议在时间上与1分钟Apgar评分的改善有关,并减少了生命第一天后对呼吸支持的需求。在分娩室进行的总插管也显着减少。这对一线提供者的插管经验具有长期影响。
    To evaluate the association of the Neonatal Resuscitation Program, Seventh Edition changes on term infants born with meconium-stained amniotic fluid (MSAF).
    We evaluated the effect of no longer routinely intubating nonvigorous term infants born with MSAF in 14 322 infants seen by the resuscitation team from January 1, 2014 to June 30, 2017 in a large, urban, academic hospital.
    Delivery room intubations of term infants with MSAF fell from 19% to 3% after the change in guidelines (P = <.0001). The rate of all other delivery room intubations also decreased by 3%. After the implementation of the Seventh Edition guidelines, 1-minute Apgar scores were significantly more likely to be >3 (P = .009) and significantly less likely to be <7 (P = .011). The need for continued respiratory support after the first day of life also decreased. Admission rates to the NICU, length of stay, and the need for respiratory support on admission were unchanged.
    Implementation of the Neonatal Resuscitation Program, Seventh Edition recommendations against routine suctioning nonvigorous infants born with MSAF was temporally associated with an improvement in 1-minute Apgar scores and decreased the need for respiratory support after the first day of life. There was also a significant decrease in total intubations performed in the delivery room. This has long-term implications on intubation experience among frontline providers.
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  • 文章类型: Editorial
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  • 文章类型: Comparative Study
    The Japan Resuscitation Council (JRC) updated the guidelines for neonatal cardiopulmonary resuscitation in 2010, which recommended appropriate oxygen supplementation under the assessment of oximetry, with continuous positive airway pressure (CPAP) as a consideration in the delivery room. Whether this update has resulted in an improvement of respiratory stabilization in term neonates has not been well investigated to date.
    The aim of this study is to evaluate the impact of the update of the JRC Guidelines in 2010 on the frequency of respiratory support for term neonates within 24 h of life in the nursery or neonatal intensive care unit (NICU).
    We conducted a retrospective, single-center study using data of term neonates born between 2008 and 2009 (defined as \'group 1\', before the update of the guidelines), and between 2011 and 2012 (defined as \'group 2\', after the update of the guidelines). We compared resuscitation procedures in the delivery room and respiratory support in the nursery or NICU within 24 h of life between the two groups. Respiratory support included oxygen therapy, nasal CPAP and mechanical ventilation.
    A total of 5,036 infants were analyzed. In group 2, oxygen administration in the delivery room was significantly decreased (38.9 vs. 22.1%, p < 0.001) and face mask CPAP in the delivery room increased (1.7 vs. 11.1%, p < 0.001). The prevalence of respiratory support within 24 h of life in the nursery or NICU increased significantly in group 2 (group 1, 6.8% vs. group 2, 16.6%, p < 0.001).
    The update of the JRC Guidelines in 2010 resulted in an increase of respiratory support for term infants within 24 h of life.
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  • 文章类型: Journal Article
    背景:先前的研究报道了定量脐带葡萄糖-6-磷酸脱氢酶(G6PD)的参考下限(LRL),但是他们没有使用认可的国际统计方法。使用通用标准期望产生更多真实的发现。因此,我们的目的是通过使用国际临床化学联合会(IFCC)和临床和实验室标准研究所(CLSI)认可的用于参考区间估计的统计分析,来估计健康足月新生儿定量G6PD检测的LRL.
    方法:这项横断面回顾性研究在阿卜杜勒阿齐兹国王医院进行,沙特阿拉伯,2010年3月至2012年6月。该研究监测了一个阿拉伯穆斯林部落的母亲所生的连续新生儿,该部落被认为G6PD缺乏症的患病率较低。包括满足以下标准的新生儿:足月分娩(37周);没有进入特殊护理托儿所;没有光疗治疗;直接抗球蛋白试验阴性;女性新生儿的父亲来自同一母亲部落。通过自动试剂盒分光光度法测量G6PD活性(单位/克血红蛋白)。本研究使用IFCC和CLSI认可的统计分析来进行参考区间估计。2.5百分位数和相应的95%置信区间(CI)估计为LRL,无论是存在还是不存在异常值。
    结果:207名男性和188名女性足月新生儿脐血定量G6PD检测符合纳入标准。Horn方法检测到20个G6PD值作为异常值(8个男性和12个女性)。在仅不存在异常值的情况下,定量脐带G6PD值的分布表现出正态分布。Harris-Boyd方法和比例标准显示组合性别LRL是可靠的。存在异常值的组合引导LRL为10.0(95%CI:7.5-10.7),不存在异常值的组合参数LRL为11.0(95%CI:10.5-11.3)。
    结论:这些结果有助于足月新生儿脐带G6PD定量检测的LRL。当预分析因素和测试方法具有可比性并且满足IFCC-CLSI转移要求时,它们可转移到另一个实验室。我们建议在没有异常值的情况下使用估计的LRL,因为将G6PD缺陷的新生儿错误标记为正常是无法忍受的,而将G6PD正常的新生儿错误标记为缺陷是可以忍受的。
    BACKGROUND: Previous studies have reported the lower reference limit (LRL) of quantitative cord glucose-6-phosphate dehydrogenase (G6PD), but they have not used approved international statistical methodology. Using common standards is expecting to yield more true findings. Therefore, we aimed to estimate LRL of quantitative G6PD detection in healthy term neonates by using statistical analyses endorsed by the International Federation of Clinical Chemistry (IFCC) and the Clinical and Laboratory Standards Institute (CLSI) for reference interval estimation.
    METHODS: This cross sectional retrospective study was performed at King Abdulaziz Hospital, Saudi Arabia, between March 2010 and June 2012. The study monitored consecutive neonates born to mothers from one Arab Muslim tribe that was assumed to have a low prevalence of G6PD-deficiency. Neonates that satisfied the following criteria were included: full-term birth (37 weeks); no admission to the special care nursery; no phototherapy treatment; negative direct antiglobulin test; and fathers of female neonates were from the same mothers\' tribe. The G6PD activity (Units/gram Hemoglobin) was measured spectrophotometrically by an automated kit. This study used statistical analyses endorsed by IFCC and CLSI for reference interval estimation. The 2.5th percentiles and the corresponding 95% confidence intervals (CI) were estimated as LRLs, both in presence and absence of outliers.
    RESULTS: 207 males and 188 females term neonates who had cord blood quantitative G6PD testing met the inclusion criteria. Method of Horn detected 20 G6PD values as outliers (8 males and 12 females). Distributions of quantitative cord G6PD values exhibited a normal distribution in absence of the outliers only. The Harris-Boyd method and proportion criteria revealed that combined gender LRLs were reliable. The combined bootstrap LRL in presence of the outliers was 10.0 (95% CI: 7.5-10.7) and the combined parametric LRL in absence of the outliers was 11.0 (95% CI: 10.5-11.3).
    CONCLUSIONS: These results contribute to the LRL of quantitative cord G6PD detection in full-term neonates. They are transferable to another laboratory when pre-analytical factors and testing methods are comparable and the IFCC-CLSI requirements of transference are satisfied. We are suggesting using estimated LRL in absence of the outliers as mislabeling G6PD-deficient neonates as normal is intolerable whereas mislabeling G6PD-normal neonates as deficient is tolerable.
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