status

status
  • 文章类型: Journal Article
    背景:关于受过职业培训的注册护士在学校和实践社区实习期间的社会化如何影响他们的感知,以及与认证护理助理的工作关系。
    目的:本文研究,首先,注册护士学生如何内化教师传达的关于认证护理助理的看法和话语,导师和其他学生在学校和实践社区的社会化过程中。第二,它检查了这种社会化如何形成学生的感知,以及与认证护理助理的实际工作关系。
    方法:使用解释性框架的定性描述性和探索性研究。
    方法:对15名注册护士学生进行了个人深入访谈,这些学生都是在培训的第三或第四年。
    结果:研究结果表明,在学校中,很少明确讨论注册护士学生和注册护理助理之间的任务划分和工作关系。然而,教师和学生含蓄地和明确地传达了认证护理助理的地位较低,将后者的角色描述为劣等和协助注册护士的角色。在实践社区实习期间,一些学生在直接与认证的护理助理合作时最初会调整这种看法,他们通常在培训的第一年是他们的导师,将认证的护理助理视为平等,并强调两个职业群体的相互依存性。然而,在他们的训练中,注册护士学生开始与毕业的注册护士有更多的联系,并再现了主要的看法和话语,即认证的护理助理是劣等的,应该支持注册护士,从而延续普遍的地位差异和不平等。
    结论:研究结果将帮助培训中心和实践社区的护士教育工作者了解如何使用教育来结束普遍存在的地位差异,并促进不同护理名称之间的相互尊重和公平。
    BACKGROUND: Limited knowledge exists about how the socialization of vocationally trained registered nurses both at school and during internships in the community of practice influences their perception of, and working relationship with certified nursing assistants.
    OBJECTIVE: This paper studies, first, how registered nurse students internalize the perceptions and discourses about certified nursing assistants conveyed by teachers, mentors and other students during their socialization at school and in the community of practice. Second, it examines how this socialization forms student\'s perception of, and actual working relationship with certified nursing assistants.
    METHODS: Qualitative descriptive and exploratory study using an interpretative framework.
    METHODS: Individual in-depth interviews were conducted with 15 registered nurse students that were in their third or fourth year of training.
    RESULTS: The findings reveal that at school the division of tasks and working relationship between registered nurse students and certified nursing assistants was very rarely discussed explicitly. However, teachers and students implicitly and explicitly conveyed that certified nursing assistants have lower status, describing the latter\'s role as inferior and as assisting to the role of registered nurses. During internships in the community of practice, some students initially adjust this perception when directly working with certified nursing assistants, who generally are their mentor in the first years of training, consider certified nursing assistants as equal and highlight the interdependence of the two occupational groups. Yet, further in their training, registered nurse students start to relate more to graduated registered nurses and reproduce the dominant perception and discourse that certified nursing assistants are inferior and supposed to support registered nurses, thereby perpetuating pervasive status differences and inequality.
    CONCLUSIONS: Findings will assist nurse educators both in training centers and in the community of practice to understand how education can be used to end pervasive status differences and foster mutual respect and equity between different designations in nursing.
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  • 文章类型: Journal Article
    第一颗恒磨牙(FPM)是口腔中出现的第一颗恒牙,它们在牙列中起着重要的作用,牙科发展,和闭塞。由于早期萌出,FPM是最容易患龋齿的牙齿。FPMs的流失有许多不利的后果。许多以前的研究都集中在年轻的年龄组。据我们所知,有关沙特阿拉伯成年人FPM状况的文献中需要报道更多的最新数据.该研究旨在评估利雅得患者样本中成人永久性第一磨牙的状况。方法从牙科大学医院的患者记录中进行横断面回顾性研究,牙科学院,沙特国王大学(KSU),在获得道德批准后。在KSU看到的810名18岁及以上患者的全景图像,牙科学院,进行了检查以评估FPM的状态。在2017年至2022年之间,出于各种牙科原因进行了全景检查。患者分为三个年龄组:18-30岁,31-50岁和>50岁。以特定形式收集数据并进行分析。牙齿缺失的患病率,以及修复的龋齿,被记录下来。此外,记录了有关修复类型的更多信息。关于年龄的研究结果的相关性,性别,侧面,对所有病例进行下颌测定,并采用卡方检验。P值小于0.05被认为具有统计学意义。结果共对810例患者进行了全景X线照片研究。全景式男性研究对象为382名(47.2%),女性为427人(52.8%)。其中三百三十九人(339人;41.9%)年龄在30岁以下,327人(40.4%)在31-50岁年龄组,其余144人(17.8%)年龄在50岁以上。第1磨牙缺失的患病率为16齿145颗(17.9%),26齿147颗(18.1%),36齿207颗(25.5%),46齿188颗(23.2%)。在年龄组和性别与第一磨牙缺失牙齿之间没有发现统计学上的显着关联(p=0.848和p=0.159)。百分之十九(19.13%)的患者只有一名漏诊FPM,12.3%的患者有两个,其中6.29%的人有三颗FPM牙齿缺失。五分之五(5.55%)的患者有四个缺失的FPM。在整个样本中,共有56.8%(242)的X射线照片没有显示任何缺失的牙齿。下颌FPM(35.2%)的缺失频率高于上颌骨(14.8%),左下颌象限FPM缺失率略高(25.55%)。统计上,在不同年龄组中,失踪FPM的数量之间存在显着关联,p值<0.0001。最恢复的,carious,替换的牙齿是下颌左磨牙,牙齿颜色修复是最常用的修复方法。结论在本研究人群中发现第一恒磨牙(FPM)缺失的患病率较高。这需要更多的意识和预防措施来保护如此重要的牙齿,因此减少了对复杂程序的需求。
    Introduction The first permanent molars (FPMs) are the first permanent teeth to emerge in the oral cavity, which have an important role in dentition, dental development, and occlusion. FPMs are the most susceptible teeth to caries due to early eruption. There are many adverse consequences related to losing FPMs. Many of the previous studies focused on younger age groups. To the best of our knowledge, there needs to be more newly updated data reported in the literature regarding the status of FPMs in adults in Saudi Arabia. The study aimed to assess the status of permanent first molars among adults in a sample of patients in Riyadh. Methods A cross-sectional retrospective study was conducted from the records of patients in the Dental University Hospital, College of Dentistry, King Saud University (KSU), after obtaining ethical approval. Panoramic images of 810 patients ages 18 and above who were seen at KSU, College of Dentistry, were examined to assess the status of FPMs. A panoramic examination was undertaken for various dental reasons in the time between the years 2017 and 2022. Patients were divided into three age groups: 18-30, 31-50, and >50 years. Data were collected in a particular form and analyzed. The prevalence of missing teeth, as well as restored and carious teeth, were recorded. In addition, further information regarding the type of restoration was recorded. Correlations of the findings regarding age, gender, side, and jaw were determined for all cases and were performed using the chi-square test. P-values less than 0.05 were considered statistically significant. Results A total of 810 patients\' panoramic radiographs were studied. Panoramic male study subjects were 382 (47.2%), and females were 427 (52.8%). Three-hundred thirty-nine (339; 41.9%) of them were of less than 30 years of age, 327 (40.4%) were in the age group of 31-50 years, and the remaining 144 (17.8%) were above 50 years of age. The prevalence of missing first molar teeth was 145 (17.9%) for teeth 16, 147 (18.1%) for teeth 26, 207 (25.5%) for teeth 36, and 188 (23.2%) for teeth 46. No statistically significant association was found between the age groups and gender and the first molar missing teeth (p=0.848 & p=0.159). Nineteen point thirteen percent (19.13%) of patients had only one missing FPM, 12.3% of patients had two, and 6.29% of them had three missing FPM teeth. Five point fifty-five percent (5.55%) of patients had four missing FPMs. A total of 56.8% (242) radiographs in the overall sample did not show any missing teeth. The mandibular FPMs (35.2%) were found missing more frequently than their maxillary counterparts (14.8%), and the left mandibular quadrant showed a slightly higher rate of missing FPM (25.55%). Statistically, a significant association was seen between the number of missing FPM among different age groups, p-value <0.0001. The most restored, carious, and replaced tooth was the mandibular left molar, and tooth-color restoration was the most commonly used restoration. Conclusion A high prevalence rate of missing first permanent molars (FPMs) was found in this study population. This calls for more awareness and preventive measures to preserve such significant teeth, therefore reducing the need for complex procedures. Further prospective studies on a larger population are needed to comprehensively evaluate the status of FPMs.
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  • 文章类型: Journal Article
    背景:收入不平等对健康的缓慢而阴险的影响意味着它们的影响可能很难揭示,需要很多年才能变得明显。这些影响也可以根据主观地位和种族而有所不同,这使得收入不平等与健康之间的关系难以理解。对急性应激的心血管反应指示未来的健康结果。
    目的:研究中短期收入不平等是否影响心血管对急性应激的反应,同时考虑种族和主观地位。
    方法:参与MIDUS生物标志物数据项目的1155人可获得参与者的居住状态。此详细信息用于合并MIDUS生物标志物数据项目之前1、5、10和15年的相关美国州级不平等数据,该项目评估了心血管对急性压力的反应。
    结果:我们的分析表明,前5、10和15年的不平等与心血管对急性应激的反应之间存在关联。主观社区地位与黑人和少数民族成员身份相互作用,影响了不平等与心血管反应之间的联系。
    结论:在收入不平等程度很高的州,较不健康的心血管反应是明显的。但是,较低的主观社区地位以及黑人和少数民族成员与收入不平等互动,因此其影响取决于州一级的不平等。这些发现扩展了有关收入不平等和健康的文献,并特别强调了将收入不平等与健康联系起来的心理生理学途径。
    BACKGROUND: The slow and insidious effects of income inequality on health means that their effects can be difficult to reveal, taking many years to become apparent. These effects can also be experienced differently according to subjective status and ethnicity making the relation between income inequality and health difficult to understand. Cardiovascular reactions to acute stress are indicative of future health outcomes.
    OBJECTIVE: To examine whether short to medium term income inequality affected cardiovascular responses to acute stress whilst accounting for ethnic groups and subjective status.
    METHODS: Participants state of residence was available for 1155 people who participated in the MIDUS biomarker data project. This detail was used to merge the relevant US state level inequality data 1, 5, 10 and 15 years prior to the MIDUS biomarker data project which assessed cardiovascular responses to acute stress.
    RESULTS: Our analysis demonstrated an association between inequality 5, 10 and 15 year prior and cardiovascular reactions to acute stress. Subjective community status and Black and minority ethnic group membership interacted to affect the association between inequality and cardiovascular reactions.
    CONCLUSIONS: In states where income inequality was high, less healthy cardiovascular responses were evident. However lower subjective community status and Black and Ethnic minority group members interacted with income inequality such that their impact was variable contingent on state level inequality. These findings extend the literature on income inequality and health and particularly highlights a psychophysiology pathway linking income inequality and health.
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  • 文章类型: Journal Article
    先前的研究已经证明了与学习相关的压力源对医学生心理健康的负面影响。已经发现,社会资源,如社会身份,双重身份和社会支持有助于缓冲负面的心理健康结果。值得注意的是,社会地位被发现会削弱压力和抑郁症状之间的联系。基于这些发现,本研究调查了社会资源(即,社会认同,社会支持,双重身份和地位)减轻了与学习相关的压力源对承担过多压力负担的医学生的心理健康的影响。
    数据收集基于问卷(在线和纸笔),该问卷分发给北莱茵-威斯特法伦州的医学生,德国。样本(224名参与者)包括77.2%的女性和22.8%的男性医学生(36.2%的人类医学学生(HMS)和63.8%的牙科医学学生(DMS))。问卷包括图形量表和标准化问卷。我们调查了人口统计数据,与学习相关的压力源(即学业成绩,临床实践,教师关系)和抑郁症状作为结果,和社会认同,社会支持,作为主持人的双重身份和地位。使用SPSS25forWindows进行分析。
    我们发现与研究相关的应激源和抑郁症状之间存在显著的正相关。虽然双重身份以及同学的社会支持在这些协会中成为缓冲,其他社会资源没有。关于地位,发现它仅在HMS中用作缓冲区,他们通常比牙科医学生享有更高的地位。
    这只是社会资源,如同学的支持和双重身份,但不是其他资源类型,这可以有效地缓冲与研究相关的压力源相关的抑郁症状。这些发现可以用来促进学生与同学和教师之间的关系,或者整个大学,使学生能够更好地应对压力,因此,减少抑郁症状。此外,HMS,赋予自己相对较高的地位,可以在紧张的情况下使用他们的状态作为缓冲因素,从外面可以做的事情很少。
    BACKGROUND: Previous research has demonstrated the negative effects of study-related stressors on the mental health of medical students. It has been found that social resources such as social identity, dual identity and social support help buffer negative mental health outcomes. Notably, social status has been found to weaken the connection between stress and depressive symptoms. Based on these findings, the present study investigates how social resources (i.e., social identity, social support, dual identity and status) mitigate the impact of study-related stressors on the mental health of medical students who carry an inordinate stress burden.
    METHODS: The data collection was based on a questionnaire (online and paper-pencil) which was distributed to medical students in North Rhine-Westphalia, Germany. The sample (224 participants) consisted of 77.2% female and 22.8% male medical students (36.2% human medicine students (HMS) and 63.8% dental medicine students (DMS)). The questionnaire included graphical scales and standardized questionnaires. We investigated demographic data, study-related stressors (i.e. academic performance, clinical practice, faculty relations) and depressive symptoms as outcomes, and social identity, social support, dual identity and status as moderators. The analyses were performed using SPSS 25 for Windows.
    RESULTS: We found significant positive associations between study-related stressors and depressive symptoms. While dual identity as well as social support by fellow students emerged as buffers in these associations, the other social resources did not. As regards status, it was found to work as a buffer only in HMS, who typically enjoy a significantly higher status than dental medical students.
    CONCLUSIONS: It is only social resources such as support from fellow students and dual identity, but not other resource types, that can be effective buffers against depressive symptoms associated with study-related stressors. These findings can be used to promote students\' identities in relation to both fellow students and the faculty, or the university as a whole, enabling students to better cope with stress and, thus, suffer less from depressive symptoms. Furthermore, the HMS, who ascribe a relatively high status to themselves, can use their status as a buffering factor in stressful situations, in which little can be done from the outside.
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  • 文章类型: Journal Article
    目的:本研究的目的是验证Alford等人提出的老年人硬膜下血肿(SHE)评分。作为65岁以上非创伤性/轻度创伤急性硬膜下血肿(aSDH)患者的死亡率预测指标。此外,我们进一步评估了与不良结局相关的预测因素.
    方法:根据年龄对患者进行评分(如果患者年龄超过80岁,则给予1分),GCS入场(GCS5-121分,GCS3-42分),和SDH体积(体积50mL为1点)。点的总和确定SHE分数。进行多因素logistic回归分析以确定与30天死亡率相关的其他独立危险因素。
    结果:我们评估了2008年至2020年间在我们机构接受治疗的131例aSDH患者。我们观察到Alford等人发表的30天死亡率相同。:SHE0:4.3%vs.3.2%,p=1.0;SHE1:12.2%vs.13.1%,p=1.0;SHE2:36.6%vs.32.7%,p=0.8;SHE3:97.1%vs.95.7%,p=1.0和SHE4:100%与100%,p=1.0。此外,无论SHE评分如何,18例出现癫痫持续状态(SE)的患者死亡率均为100%。各组中SE的分布为:SHE1为1,SHE2为6,SHE3为9,SHE4为2。逻辑回归显示,手术撤离是癫痫发作的唯一重要危险因素。所有发生SE的患者均接受手术治疗(p=0.0065)。此外,SHE3和4在手术和保守治疗之间的结果没有差异。
    结论:SHE评分是老年患者轻微创伤急性硬膜下血肿的可靠死亡率预测指标。此外,我们认为,在接受手术后送的患者中,癫痫持续状态是一个重要的预期寿命限制因素.
    OBJECTIVE: The aim of this study was the verification of the Subdural Hematoma in the Elderly (SHE) score proposed by Alford et al. as a mortality predictor in patients older than 65 years with nontraumatic/minor trauma acute subdural hematoma (aSDH). Additionally, we evaluated further predictors associated with poor outcome.
    METHODS: Patients were scored according to age (1 point is given if patients were older than 80 years), GCS by admission (1 point for GCS 5-12, 2 points for GCS 3-4), and SDH volume (1 point for volume 50 mL). The sum of points determines the SHE score. Multivariate logistic regression analysis was performed to identify additional independent risk factors associated with 30-day mortality.
    RESULTS: We evaluated 131 patients with aSDH who were treated at our institution between 2008 and 2020. We observed the same 30-day mortality rates published by Alford et al.: SHE 0: 4.3% vs. 3.2%, p = 1.0; SHE 1: 12.2% vs. 13.1%, p = 1.0; SHE 2: 36.6% vs. 32.7%, p = 0.8; SHE 3: 97.1% vs. 95.7%, p = 1.0 and SHE 4: 100% vs. 100%, p = 1.0. Additionally, 18 patients who developed status epilepticus (SE) had a mortality of 100 percent regardless of the SHE score. The distribution of SE among the groups was: 1 for SHE 1, 6 for SHE 2, 9 for SHE 3, and 2 for SHE 4. The logistic regression showed the surgical evacuation to be the only significant risk factor for developing the seizure. All patients who developed SE underwent surgery (p = 0.0065). Furthermore, SHE 3 and 4 showed no difference regarding the outcome between surgical and conservative treatment.
    CONCLUSIONS: SHE score is a reliable mortality predictor for minor trauma acute subdural hematoma in elderly patients. In addition, we identified status epilepticus as a strong life-expectancy-limiting factor in patients undergoing surgical evacuation.
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  • 文章类型: Journal Article
    许多中青年维持性血液透析患者预后差,在长期治疗过程中会遇到一系列问题,因此容易产生污名。本研究旨在分析中青年维持性血液透析患者的病耻感,并探讨其影响因素。本研究采用方便抽样的横断面描述性研究方法,纳入2020年11月至2021年2月上海交通大学附属第六人民医院的97名患者。社会影响量表,人口统计问卷,和血液透析指标用于调查。比较血液透析患者的生化指标。中青年维持性血液透析患者存在中等程度的病耻感。低收入的病人,更年轻,是男性,长期血液透析和失业患者的病耻感评分明显高于其他患者(P<0.05)。年龄,性别,职业状况,通过多元回归分析发现,家庭年收入和血液透析时间是影响中青年维持性血液透析患者病耻感的主要因素。在我们的样本中,对血液透析相关病耻感的看法很常见。低收入的病人,更年轻,是男性,长期血液透析和就业有较高的污名,值得临床医务工作者关注。需要复制研究来证实这些发现。
    Many young and middle-aged maintenance hemodialysis patients suffer a poor prognosis, experience a series of problems during long-term treatment and are thus prone to stigma. This study was designed to analyze stigma in young and middle-aged maintenance hemodialysis patients and explore its influencing factors. This study was conducted as a cross-sectional descriptive study with a convenience sampling method and included 97 patients from Shanghai Jiao Tong University Affiliated Sixth People\'s Hospital between November 2020 and February 2021. The Social Impact Scale, a demographic questionnaire, and hemodialysis indicators were used in the investigation. Patient biochemical indexes from hemodialysis were compared. Young and middle-aged maintenance hemodialysis patients had a medium level of stigma. Patients who had low income, were younger, were male, had long-term hemodialysis and were unemployed had significantly higher stigma scores than other patients (P < 0.05). Age, gender, occupational status, annual household income and the duration of hemodialysis were found to be the main factors related to stigma in young and middle-aged maintenance hemodialysis patients by multiple regression analysis. Perceptions of hemodialysis-related stigma were common in our sample. Patients who had low income, were younger, were male, had long-term hemodialysis and were employed had a higher level of stigma, which deserves attention from clinical medical workers. Replication studies are needed to confirm these findings.
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  • 文章类型: Journal Article
    Conflicts of interest (COI) in health and medicine have been the source of considerable public and professional debate. Much of this debate has focused on financial, rather than non-financial COI, which is a significant lacuna because non-financial COI can be just as influential as financial COI. In an effort to explore the nature and effects of non-financial, as well as financial COI, we conducted semi-structured interviews with eleven Australian medical professionals regarding their experiences of, and attitudes towards, COI. We found that this group of medical professionals saw non-financial interests-most notably the pursuit of status and respect and the avoidance of stigma-as potentially conflicting with other important interests (such as patient care).
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  • 文章类型: Journal Article
    BACKGROUND: Many western countries have problems recruiting and retaining medical specialists. In Sweden there is a lack of primary care doctors and psychiatrists. Despite much research on the topic the shortage remains. We therefore set out to analyse choice of medical speciality using Bourdieu\'s theoretical concepts; cultural capital, social background and perceived status.
    METHODS: A cross-sectional questionnaire-based study of 399 alumni from the Medical School at Karolinska Institutet, Stockholm was performed. The response rate was 72% (n = 286); 262 of the respondents were in training to become specialists. Specialties were categorized as primary care, psychiatry, internal medicine, and surgical and hospital service specialties. To study the associations between medical specialties and cultural capital, we used multinomial regression analyses. Variables that showed a significant association with medical specialties were included in an adjusted multivariable model. These results were presented as odds ratios: the odds that a particular speciality is chosen in comparison to a choice of surgery as a speciality, based on perceptions of high status.
    RESULTS: The results were analysed using Bourdieu\'s theoretical concepts of cultural capital, in the form of educational capital and social prestige. We found distinctive differences in perceived status for the examined speciality groups, ranging from 70% high status for surgery down to 6% high status for geriatrics and primary care. Perceived status was also associated with respondents\' own speciality choice, presented as an odds ratio. Our data did not show any associations between speciality choice and educational capital. We also included sociodemographic data.
    CONCLUSIONS: The field of medicine is according to Bourdieu an arena for power struggles. Knowledge of the distinctive differences in perceived status between medical specialties can be an asset particularly in relation to recruitment and retainment of specialist doctors. Our results could be used to identify specialities where perceptions of low status may be contributing to a shortage of specialists.
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  • 文章类型: Journal Article
    横断面(CS)调查表明,急性炎症患者的血浆铁蛋白(pF)较高,和较低的视黄醇结合蛋白(RBP)和锌(pZn)的浓度比没有。在感染负担很高的人群中,将校正因子(CFs)或回归校正(RCs)应用于生物标志物,以估计针对炎症调整后的微量营养素(MN)缺乏的患病率.这假设有和没有炎症的个体具有相同的营养状况,情况可能并非如此。
    这项研究的目的是调查短期,急性期蛋白的纵向个体内变化(C反应蛋白[CRP],α-1-酸性糖蛋白[AGP])和MN状态的生物标志物(pF,可溶性转铁蛋白受体[sTfR],RBP,和pZn),并将它们与CS的差异进行比较。
    从451名6-23个月无症状的布基纳法索儿童中获得了21天的血液样本。要计算CFs,炎症定义为CRP>5mg/L或AGP>1g/L,或者两者兼而有之。RC方法将MN生物标志物调整为研究群体内的推测健康的参考点(10%的CRP或AGP浓度)。CSCFs和RCs是根据朴素回归模型估计的,将来自同一个孩子的观察结果视为独立的。纵向CFs和RC,评估CRP和/或AGP个体内变化的影响,是从一般线性模型估计的,考虑重复措施。
    在CS模型中,几何平均pF和sTfR浓度高出8-340%,RBP和pZn降低2-18%,有炎症的孩子比没有炎症的孩子。除了sTfR,在观察期间炎症状态发生改变的个体中,生物标记物浓度在相同方向和相似程度上存在差异.尽管与纵向模型相比,用CS调整后的几何平均MN浓度存在显着差异,CS和纵向校正模型中MN缺陷的估计患病率相似.
    在CS调查中调整个体之间炎症的MN生物标志物的CF和RC方法是在可比人群中进行数据收集和程序决策的有效方法。这项研究在clinicaltrials.gov注册为NCT00944853。
    Cross-sectional (CS) surveys indicate that individuals with acute inflammation have higher plasma ferritin (pF), and lower retinol-binding protein (RBP) and zinc (pZn) concentrations than those without. In populations with a high burden of infection, correction factors (CFs) or regression corrections (RCs) are applied to biomarkers to estimate the prevalence of micronutrient (MN) deficiencies adjusted for inflammation. This assumes that individuals with and without inflammation have the same nutritional status, which may not be the case.
    The aim of this study was to investigate relations between short-term, longitudinal within-individual changes in acute phase proteins (C-reactive protein [CRP], α-1-acid glycoprotein [AGP]) and biomarkers of MN status (pF, soluble transferrin receptor [sTfR], RBP, and pZn), and compare them to CS differences.
    Two blood samples were obtained 21 d apart from 451 asymptomatic Burkinabé children aged 6-23 mo. To calculate CFs, inflammation was defined as CRP >5 mg/L or AGP >1 g/L, or both. The RC approach adjusted MN biomarkers to a presumably healthy reference point within the study population (10th percentile CRP or AGP concentration). CS CFs and RCs were estimated from a naive regression model, treating observations from the same children as independent. Longitudinal CFs and RCs, to estimate effects of within-individual changes in CRP and/or AGP, were estimated from general linear models, accounting for repeated measures.
    In CS models, geometric mean pF and sTfR concentrations were 8-340% greater, and RBP and pZn 2-18% lower, in children with inflammation than those without. Except for sTfR, biomarker concentrations differed in the same direction and by similar magnitude within individuals whose inflammation status changed during the observation period. Although geometric mean MN concentrations differed significantly when adjusted with CS compared with longitudinal models, the estimated prevalence of MN deficiencies in CS and longitudinally adjusted models was similar.
    The CF and RC approaches to adjust MN biomarkers for inflammation between individuals in CS surveys are valid approaches for data collection and programmatic decisions in comparable populations. This study was registered at clinicaltrials.gov as NCT00944853.
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  • 文章类型: Journal Article
    Objective: To analyze the status and its factors associated with HIV/AIDS- \"90-90-90\" -treatment-target in Shandong province, China. Methods: Data regarding testing, treatment on HIV/AIDS in Shandong province by December 31, 2015 was collected. Chi-square test and logistic regression model were used to analyze related factors associated with the \"90-90-90\" -treatment-target. Results: Of the 11 700 estimated HIV/AIDS, 61.2% were diagnosed, of whom 74.4% had received Highly active antiretroviral therapy (HAART) . More than 80% of the HIV/AIDS on HAART reached the criteria on viral suppression. HIV/AIDS infected by homosexual contacts were less likely to seek for diagnosis (P<0.05). HIV/AIDS lived in Qingdao city (OR=1.30, 95%CI: 1.05-1.60), Yantai city (OR=1.53, 95%CI: 1.02-2.31) and Weihai city (OR=1.96, 95%CI: 1.07-3.58) were more likely to receive HAART. HIV/AIDS patients that infected through homosexual or (OR=0.12, 95%CI:0.06-0.24) or heterosexual contacts (OR=0.13, 95%CI: 0.07-0.26), through injecting drug use (OR=0.08,95%CI: 0.03-0.17) or being diagnosed at the custodial institutions (OR=0.29, 95%CI: 0.21-0.41) were less likely to receive HAART. HIV/AIDS patients who received HAART at medical institutions (OR=1.81, 95%CI: 1.05-3.47) were more likely to meet the level of Viral load (VL) suppression. However, those who were infected through homosexual (OR=0.43, 95%CI: 0.25-0.75) or heterosexual contacts (OR=0.49, 95%CI: 0.28-0.81) or diagnosed at the custodial institutions (OR=0.48, 95%CI: 0.28-0.80) were less likely to meet the criteria set for VL suppression. Conclusions: There was a gap between the status of testing/treatment and the target on HIV/AID \"90-90-90\" -treatment,especially on the target set for testing, in Shandong Province. Both HIV testing and comprehensive care services need to be strengthened.
    目的: 分析山东省2015年艾滋病防治策略\"三个90%\"(即90%诊断、90%治疗及90%有效)\"目标的进展情况及相关影响因素。 方法: 收集山东省现存活HIV感染者/AIDS患者(HIV/AIDS)检测发现、接受高效抗反转录病毒治疗(HAART)服务的相关信息,分析进展情况。采用χ(2)检验进行单因素分析,多因素logistic回归模型进行多因素分析。 结果: 2015年12月31日,山东省估计现存活HIV/AIDS有11 700例,检测发现率61.2%,HAART率74.4%,病毒载量(VL)抑制率81.8%。经同性传播的HIV/AIDS检测发现比例较低(P<0.05)。青岛市(OR=1.30,95%CI:1.05~1.60)、烟台市(OR=1.53,95%CI:1.02~2.31)和威海市(OR=1.96,95%CI:1.07~3.58)的HIV/AIDS接受HAART的比例较高;同性传播(OR=0.12,95%CI:0.06~0.24)、异性传播(OR=0.13,95%CI:0.07~0.26)、注射吸毒传播(OR=0.08,95%CI:0.03~0.17),羁押场所检测发现(OR=0.29,95%CI:0.21~0.41)的HIV/AIDS接受HAART比例较低;医疗机构接受HAART服务的HIV/AIDS(OR=1.81,95%CI:1.05~3.47)的VL抑制比例较高;同性传播(OR=0.43,95%CI:0.25~0.75)、异性传播(OR=0.49,95%CI:0.28~0.81),羁押场所检测发现(OR=0.48,95%CI:0.28~0.80)的HIV/AIDS的VL抑制比例较低。 结论: 山东省2015年现存活HIV/AIDS的检测发现率、HAART率和VL抑制率与2020年实现的艾滋病防治策略\"三个90%\"目标仍有一定差距,尤其是检测发现目标。需加强检测和艾滋病综合关怀服务。.
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