该病例报告介绍了一名72岁的男性,患有长期复发性呼吸道乳头状瘤病(RRP)。他已经接受了多次治疗,包括明显的紧急手术气道,然后进行气管成形术修复。复杂RRP的现代管理应包括局部分解和系统方法。系统性贝伐单抗(阿瓦斯汀)作为一种有效的治疗选择已经显示出一些初步的成功,除了其他药物如pembrolizumab。其他未来的护理策略可能包括HPV疫苗接种和其他佐剂;据报道,疫苗接种有可能大大降低RRP的发生率。
This case report presents a 72-year-old man with longstanding recurrent respiratory papillomatosis (RRP). He has undergone multiple procedures for the condition, including an apparent urgent surgical airway followed by tracheoplasty repair. Modern management of complicated RRP should include both local debulking and systemic approaches. Systemic bevacizumab (Avastin) has shown some initial success as an effective treatment option, in addition to other medications such as pembrolizumab. Other future care strategies may include an HPV vaccination and other adjuvants; vaccination has been reported to have the possibility of drastically reducing the incidence of RRP.