spine surgery

脊柱外科
  • 文章类型: Case Reports
    皮质骨轨迹(CBT)技术已成为腰椎融合的微创方法,但可能导致假关节炎和硬件故障。本报告介绍了一例成功的椎弓根螺钉翻修的患者,该患者先前使用新的“两步”技术失败的L2和L3融合,包括(1)使用美敦力EM800N隐形MIDAS导航MR8钻具系统(美敦力,都柏林,爱尔兰)和(2)将Solera4.75ATS(锥头螺钉)与导航POWEREASE™(Medtronic)放置,这里第一次描述。这种方法包括利用神经导航和专门的仪器,通过旧皮质螺钉轨迹的路径安全地放置椎弓根螺钉,解决与CBT硬件故障相关的挑战。
    The cortical bone trajectory (CBT) technique has emerged as a minimally invasive approach for lumbar fusion but may result in pseudoarthrosis and hardware failure. This report presents a case of successful pedicle screw revision in a patient with previous failed L2 and L3 fusion using a novel \"two-step\" technique, including (1) drilling a new trajectory with Medtronic EM800N Stealth MIDAS Navigated MR8 drill system (Medtronic, Dublin, Ireland) and (2) placement of Solera 4.75 ATS (awl-tapped screws) with navigated POWEREASE™ (Medtronic), described here for the first time. This method involves utilizing neuronavigation and specialized instruments to safely place pedicle screws through the path of the old cortical screw trajectory, addressing the challenges associated with CBT hardware failure.
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  • 文章类型: Journal Article
    背景:在结果测量仪器中建立实际上对患者有意义的变化阈值是至关重要的。这个概念被称为最小临床重要差异(MCID)。我们总结了与脊柱外科相关的可用MCID计算方法,并概述关键考虑因素,接下来是如何计算MCID的逐步工作示例,使用公开可用的数据,使读者能够自己遵循计算。
    方法:总结了13种MCID计算方法,包括基于锚的方法,基于分布的方法,可靠的变化指数,比基线减少30%,社会比较法和德尔菲法。所有方法,除了后两者,用于计算MCID以改善ZCQ症状严重程度。腿部疼痛的数字评定量表和日本骨科协会背痛评估问卷行走能力领域被用作锚。
    结果:改善ZCQ症状严重程度的MCID范围为0.8至5.1。平均而言,基于分布的方法产生较低的MCID值,比基于锚的方法。达到计算的MCID阈值的患者百分比范围为9.5%至61.9%。
    结论:在脊柱研究中鼓励使用MCID计算来评估治疗的成功。基于锚的方法,依靠评估患者偏好的量表,继续成为“黄金标准”,接收器工作特性曲线方法是最佳的。在他们缺席的时候,最小可检测变化方法是可以接受的。使用统计代码和公开可用数据提供的MCID计算的解释和逐步示例可以作为规划未来MCID计算研究的指导。
    BACKGROUND: Establishing thresholds of change that are actually meaningful for the patient in an outcome measurement instrument is paramount. This concept is called the minimum clinically important difference (MCID). We summarize available MCID calculation methods relevant to spine surgery, and outline key considerations, followed by a step-by-step working example of how MCID can be calculated, using publicly available data, to enable the readers to follow the calculations themselves.
    METHODS: Thirteen MCID calculations methods were summarized, including anchor-based methods, distribution-based methods, Reliable Change Index, 30% Reduction from Baseline, Social Comparison Approach and the Delphi method. All methods, except the latter two, were used to calculate MCID for improvement of Zurich Claudication Questionnaire (ZCQ) Symptom Severity of patients with lumbar spinal stenosis. Numeric Rating Scale for Leg Pain and Japanese Orthopaedic Association Back Pain Evaluation Questionnaire Walking Ability domain were used as anchors.
    RESULTS: The MCID for improvement of ZCQ Symptom Severity ranged from 0.8 to 5.1. On average, distribution-based methods yielded lower MCID values, than anchor-based methods. The percentage of patients who achieved the calculated MCID threshold ranged from 9.5% to 61.9%.
    CONCLUSIONS: MCID calculations are encouraged in spinal research to evaluate treatment success. Anchor-based methods, relying on scales assessing patient preferences, continue to be the \"gold-standard\" with receiver operating characteristic curve approach being optimal. In their absence, the minimum detectable change approach is acceptable. The provided explanation and step-by-step example of MCID calculations with statistical code and publicly available data can act as guidance in planning future MCID calculation studies.
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  • 文章类型: Journal Article
    目的:术后肠和膀胱功能障碍(BBD)在骶脊髓节段和骶神经根手术后存在重大风险,特别是在神经肿瘤病例中。显然,需要更可靠的神经监测技术来增强脊柱手术的安全性。
    方法:我们进行了一个病例系列,包括60例手术,涉及56例患者,从2022年9月到2024年1月。我们评估了骶骨反射(球海绵体和尿道外括约肌反射)的诊断准确性,并将其与包含肛门括约肌(AS)和尿道外括约肌(EUS)记录的经颅运动诱发电位(TCMEP)进行了比较。以及具有AS和EUS记录的自发肌电图(s-EMG)。
    结果:骶骨反射在预测术后BBD方面表现出100%的特异性,灵敏度为73.33%。虽然在1个月的随访中敏感性略有下降至64.71%,总体上一直很高。有AS/EUS记录的TCMEP未发现任何术后BBD实例,而具有AS/EUS记录的s-EMG的敏感性为14.29%,特异性为97.14%。
    结论:骶骨反射监测是常规神经监测的有力辅助手段,为外科医生提供有价值的预测性见解,以潜在地减轻术后BBD的发生。
    OBJECTIVE: Postoperative bowel and bladder dysfunction (BBD) poses a significant risk following surgery of the sacral spinal segments and sacral nerve roots, particularly in neuro-oncology cases. The need for more reliable neuromonitoring techniques to enhance the safety of spine surgery is evident.
    METHODS: We conducted a case series comprising 60 procedures involving 56 patients, spanning from September 2022 to January 2024. We assessed the diagnostic accuracy of sacral reflexes (bulbocavernosus and external urethral sphincter reflexes) and compared them with transcranial motor evoked potentials (TCMEP) incorporating anal sphincter (AS) and external urethral sphincter (EUS) recordings, as well as spontaneous electromyography (s-EMG) with AS and EUS recordings.
    RESULTS: Sacral reflexes demonstrated a specificity of 100% in predicting postoperative BBD, with a sensitivity of 73.33%. While sensitivity slightly decreased to 64.71% at the 1-month follow-up, it remained consistently high overall. TCMEP with AS/EUS recordings did not identify any instances of postoperative BBD, whereas s-EMG with AS/EUS recordings showed a sensitivity of 14.29% and a specificity of 97.14%.
    CONCLUSIONS: Sacral reflex monitoring emerges as a robust adjunct to routine neuromonitoring, offering surgeons valuable predictive insights to potentially mitigate the occurrence of postoperative BBD.
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  • 文章类型: Case Reports
    硬膜内脊柱转移瘤显著损害神经功能和生活质量,需要多式联运,姑息管理,以保持活动和减轻疼痛。由于血脊髓屏障和肿瘤的放射抗性,全身化疗和放疗的有效性是有限的,分别。这凸显了考虑到神经学迅速下降的替代疗法的紧迫性。手术干预变得至关重要,专注于最大程度的肿瘤减瘤以加强疾病控制,恢复步行,缓解症状而不损害神经功能。实现这一目标需要细致的术前计划和积极的术中神经监测。将手术与辅助治疗相结合可以改善局部控制并可能延迟复发。这篇基于病例的综述强调了两例硬膜内脊柱转移瘤的手术考虑和结果。强调手术在多模式治疗中的价值。
    Intradural spinal metastases significantly impair neurological function and quality of life, necessitating multimodal, palliative management to preserve mobility and alleviate pain. The effectiveness of systemic chemotherapy and radiotherapy is limited due to the blood-spinal cord barrier and the tumours\' radioresistance, respectively. This highlights the urgency for alternative treatments given the rapid neurological decline. Surgical intervention becomes crucial, focusing on maximum tumour debulking to enhance disease control, restore ambulation, and palliate symptoms without compromising neurological function. Achieving this involves meticulous preoperative planning and aggressive intraoperative neuromonitoring. Combining surgery with adjuvant therapies may improve local control and potentially delay recurrence. This case-based review emphasizes the surgical considerations and outcomes in two cases of intradural spinal metastases, underscoring the value of surgery in multimodal therapy.
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  • 文章类型: Case Reports
    我们报告了一名48岁的男性患者,在T3和T4患有脊髓上皮样血管内皮瘤,该患者开始出现下肢感觉异常和右下肢远端无力的症状,背痛,增加步行限制,尿失禁,还有便秘.进行了安全的最大切除,在PET/CT扫描中发现残留疾病,所以决定用放射治疗,对这种治疗有很好的反应。对胸椎上皮样血管内皮瘤进行了文献综述,结果显示平均年龄为41岁,男女比例为1:0.53。主要症状是疼痛,100%的病人都有,56.8%的患者进行了广泛的手术,病灶内手术占31.8%,活检占11.4%。共有46.6%的病人接受放射治疗,只有6.6%接受化疗。患者平均随访38个月。我们建议在手术切除后进行PET/CT扫描等扩展研究。这可以作为血管内皮瘤上皮瘤患者关于转移性疾病或残留疾病的随访,这将指导我们给予辅助治疗,如放疗或化疗,为了更好地控制疾病。
    We report a 48-year-old male patient with spinal epithelioid hemangioendothelioma in T3 and T4 who began with symptoms of paresthesia in the lower limbs and distal weakness of the right lower limb, back pain, increased limitation in walking, urinary incontinence, and constipation. A safe maximum resection was performed, finding residual disease during the PET/CT scan, so it was decided to treat with radiotherapy, and there was a good response to this treatment. A literature review of epithelioid hemangioendothelioma of the thoracic spine was done which showed a mean age of presentation of 41 years and a male-female ratio of 1:0.53. The main symptom was pain, which was present in 100% of the patients, and wide surgery was performed in 56.8% of the patients, intralesional surgery in 31.8%, and biopsy in 11.4%. A total of 46.6% of patients received radiation therapy, and only 6.6% received chemotherapy. The patients had an average follow-up of 38 months. We recommend that extension studies such as PET/CT scans be performed after surgical resection. This can serve as a follow-up with hemangioendothelioma epithelioma patients about metastatic disease or residual disease that will guide us in giving adjuvant treatments, such as radiotherapy or chemotherapy, for better control of the disease.
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  • 文章类型: Case Reports
    金黄色葡萄球菌存在于大约30%的健康人群的正常皮肤和粘膜中,并且是与细菌相关的人类疾病中最常见的病原体。它们分为甲氧西林敏感的S。金黄色葡萄球菌(MSSA)和耐甲氧西林金黄色葡萄球菌(MRSA)。携带Panton-Valentine杀白细胞素基因(SA-PVL)的金黄色葡萄球菌菌株最初被认为属于MRSA组;然而,最近的报告显示,它们也属于MSSA组(MSSA-PVL)。SA-PVL常见于皮肤和软组织感染,但罕见于肌肉骨骼感染。尤其是脊椎盘炎.我们正在报告一例与携带Panton-Valentine杀白细胞素基因的MSSA相关的颈椎病和硬膜外脓肿。
    Staphylococcus aureus is found in the normal skin and mucosa of approximately 30% of healthy populations and is the most common pathogen in human disease associated with bacteria. They are divided into methicillin-sensitive S . aureus (MSSA) and methicillin-resistant S. aureus (MRSA). The S. aureus strains carrying the Panton-Valentine leukocidin genes (SA-PVL) were initially believed to belong to the MRSA group; however, recent reports showed they also belonged to the MSSA group (MSSA-PVL). SA-PVL is common in skin and soft-tissue infections but rare in musculoskeletal infections, especially in spondylodiscitis. We are reporting a case suffering from cervical spondylodiscitis and epidural abscess associated with MSSA carrying the Panton-Valentine leukocidin genes.
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  • 文章类型: Journal Article
    淋巴管瘤是淋巴畸形中的良性错构瘤,表现出多方面的临床特征。脊髓受累非常罕见,迄今报告的病例只有35例。由于它们的稀有性和变色波放射学特征,脊髓淋巴管瘤(SLs)通常被误诊;术后,因此,外科医生面临着意想不到的组织病理学诊断,相关文献很少,没有可用的治疗指南。
    这里,我们报告了一个67岁的女性,她接受了T6-T7硬膜外SL经椎间孔扩张手术,表现为痉挛性轻瘫。然后,我们介绍了关于这一主题的文献的第一次系统综述的结果,描述这种罕见疾病的临床和影像学特征以及治疗意义。
    我们的患者接受了T6-T7半椎板切除术和硬膜外肿块切除术,她的神经影像完全恢复了.18个月时无明显复发。在文学中,报道了35例SL,可分类为椎骨SL(n=18),硬膜外SL(n=10),硬膜内SL(n=3),或继发性脊髓受累的胸腔内淋巴管瘤(n=4)。针对这些类别中的每一个都采用了特定的治疗策略(手术和非手术)。
    收集有关SL的知识对于促进这种罕见疾病的正确术前识别和适当的围手术期管理至关重要。通过查阅文献并讨论一个典型的案例,我们描绘了一个框架,可以指导外科医生面对这种陌生的诊断。
    UNASSIGNED: Lymphangiomas are benign hamartomas in the spectrum of lymphatic malformations, exhibiting multifaceted clinical features. Spinal involvement is exceedingly rare, with only 35 cases reported to date. Both due to their rarity and chameleonic radiologic features, spinal lymphangiomas (SLs) are usually misdiagnosed; postoperatively, surgeons are thus confronted with an unexpected histopathological diagnosis with sparse pertinent literature and no treatment guidelines available.
    UNASSIGNED: Here, we report the case of a 67-year-old female who underwent surgery for a T6-T7 epidural SL with transforaminal extension, manifesting with spastic paraparesis. Then, we present the results of the first systematic review of the literature on this subject, delineating the clinical and imaging features and the therapeutic implications of this rare disease entity.
    UNASSIGNED: Our patient was treated with T6-T7 hemilaminectomy and resection of the epidural mass, with complete recovery of her neurological picture. No recurrence was evident at 18 months. In the literature, 35 cases of SL were reported that can be classified as vertebral SL (n = 18), epidural SL (n = 10), intradural SL (n = 3), or intrathoracic lymphangiomas with secondary spinal involvement (n = 4). Specific treatment strategies (both surgical and nonsurgical) were adopted in relation to each of these categories.
    UNASSIGNED: Gathering knowledge about SL is fundamental to promote both correct preoperative identification and appropriate perioperative management of this rare disease entity. By reviewing the literature and discussing an exemplary case, we delineate a framework that can guide surgeons facing such an unfamiliar diagnosis.
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  • 文章类型: Journal Article
    背景:评估机器人辅助的Magerl螺钉放置的准确性,并探讨影响准确性的因素。
    方法:对接受机器人辅助Magerl螺钉置入的患者进行回顾性分析。根据Gertzbein和Robbins量表评估Magerl螺钉放置的准确性。
    结果:在24例连续患者中放置了47颗Magerl螺钉。32枚Magerl螺钉比C2峡部高度窄,其中26枚为A级。15枚Magerl螺钉比C2峡部高度宽,均为B级。减压后临时固定,C2峡部高度和螺钉直径之间的差异较小,皮质破裂的可能性较高。
    结论:机器人辅助的Magerl螺钉放置的准确性非常好。减压后的临时固定以及C2峡部高度和螺钉直径之间的较小差异增加了皮质破裂的风险。
    BACKGROUND: To assess the accuracy of robot-assisted Magerl screw placement and explore the factors affecting the accuracy.
    METHODS: A retrospective analysis of patients who underwent robot-assisted Magerl screw placement was performed. The accuracy of Magerl screw placement was evaluated according to the Gertzbein and Robbins scale.
    RESULTS: 47 Magerl screws were placed in 24 consecutive patients. 32 Magerl screws were narrower than the C2 isthmus height and 26 of them were grade A. 15 Magerl screws were wider than the C2 isthmus height and all of them were grade B. Temporary fixation after decompression and a smaller difference between the C2 isthmus height and screw diameter were associated with a higher probability of cortical breach.
    CONCLUSIONS: The accuracy of robot-assisted Magerl screw placement was excellent. Temporary fixation after decompression and a smaller difference between the C2 isthmus height and screw diameter increased the risk of cortical breach.
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  • 文章类型: Journal Article
    背景:全球人口老龄化对脊柱外科医生提出了越来越大的挑战。脊柱外科的进步,包括微创技术,有更广泛的治疗选择,可能使老年患者受益。本研究旨在探讨七十岁和八十岁老人脊柱手术的临床效果。
    方法:本回顾性分析,在美国高等教育中心进行,包括70岁及以上因退行性疾病而接受选择性脊柱手术的患者。数据包括Charlson合并症指数,ASA分类,外科手术,术中和术后并发症,和再操作率。这项研究的目的是描述我们的老年患者队列的结果,并辨别七十岁和八十岁之间是否存在差异。
    结果:在符合纳入标准的120例患者中,各年龄组术前因素差异无统计学意义(p>0.05)。值得注意的是,七十年代组的平均融合水平较高(2.36vs.0.38,p=0.001),虽然八十岁组接受微创手术的比例更高(p=0.012),导致年龄最大组的总体出血减少(p<0.001)。流动性结果在七十多岁的人中更有利,而八十岁的老人倾向于保持或经历流动性下降(p=0.012)。共记录了6例(5%)术中并发症和12例(10%)术后并发症,两组之间无统计学差异。
    结论:本病例系列显示七十岁老人和八十岁老人可以通过择期脊柱手术获得良好的临床结果。脊柱外科医生应该精通老年人的临床和外科护理,提供考虑增加的合并症负担和增加的脆弱性的最佳管理。
    The aging global population presents an increasing challenge for spine surgeons. Advancements in spine surgery, including minimally invasive techniques, have broadened treatment options, potentially benefiting older patients. This study aims to explore the clinical outcomes of spine surgery in septuagenarians and octogenarians.
    This retrospective analysis, conducted at a US tertiary center, included patients aged 70 and older who underwent elective spine surgery for degenerative conditions. Data included the Charlson Comorbidity Index (CCI), ASA classification, surgical procedures, intraoperative and postoperative complications, and reoperation rates. The objective of this study was to describe the outcomes of our cohort of older patients and discern whether differences existed between septuagenarians and octogenarians.
    Among the 120 patients meeting the inclusion criteria, there were no significant differences in preoperative factors between the age groups (P > 0.05). Notably, the septuagenarian group had a higher average number of fused levels (2.36 vs. 0.38, P = 0.001), while the octogenarian group underwent a higher proportion of minimally invasive procedures (P = 0.012), resulting in lower overall bleeding in the oldest group(P < 0.001). Mobility outcomes were more favorable in septuagenarians, whereas octogenarians tended to maintain or experience a decline in mobility(P = 0.012). A total of 6 (5%) intraoperative complications and 12 (10%) postoperative complications were documented, with no statistically significant differences observed between the groups.
    This case series demonstrates that septuagenarians and octogenarians can achieve favorable clinical outcomes with elective spine surgery. Spine surgeons should be well-versed in the clinical and surgical care of older adults, providing optimal management that considers their increased comorbidity burden and heightened fragility.
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  • 文章类型: Case Reports
    我们报告了一个神经监测案例,使用运动诱发电位(MEP),在腰骶部减压和器械融合手术中检测到术中L5神经根缺陷。严重的,MEP变化之前没有出现,也没有伴随任何明显的自发性肌电图(sEMG)活动.假定L5神经支配的肌肉,包括胫骨前肌(TA),幻长伸肌(EHL)和臀大肌,是使用MEP和sEMG技术联合进行神经根监测的目标。在高级别脊椎滑脱矫正手术中,对齐左侧杆的尝试导致来自TA和EHL的MEP重复丢失和恢复循环。没有伴随的EMG警报与任何MEP变化相关,也没有从L5以上和以下神经支配的肌肉看到MEP变化。经过几次尝试,实现了杆对准,但EHL的MEP信号显著下降(下降72%)。术后,患者左侧出现明显的足下垂,3个月后恢复.这种情况有助于越来越多的证据表明,仅依靠sEMG进行脊髓神经根检查可能是不可靠的,而MEP可能会提供有关神经根通畅的更可靠数据。
    We report a case where neuromonitoring, using motor evoked potentials (MEP), detected an intraoperative L5 nerve root deficit during a lumbosacral decompression and instrumented fusion procedure. Critically, the MEP changes were not preceded nor accompanied by any significant spontaneous electromyography (sEMG) activity. Presumptive L5 innervated muscles, including tibialis anterior (TA), extensor hallucis longus (EHL) and gluteus maximus, were targets for nerve root surveillance using combined MEP and sEMG techniques. During a high-grade spondylolisthesis correction procedure, attempts to align a left-sided rod resulted in repeated loss and recovery cycles of MEP from the TA and EHL. No accompanying EMG alerts were associated with any of the MEP changes nor were MEP variations seen from muscles innervated above and below L5. After several attempts, the rod alignment was achieved, but significant MEP signal decrement (72% decrease) remained from the EHL. Postoperatively, the patient experienced significant foot drop on the left side that recovered over a period of 3 months. This case contributes to a growing body of evidence that exclusive reliance on sEMG for spinal nerve root scrutiny can be unreliable and MEP may provide more dependable data on nerve root patency.
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