背景:肉囊虫物种是多种多样的尖丛寄生虫,尽管只有两个人畜共患物种(S.hominis和S.heydorni)在牛和人之间循环。由于牛在人类食物链中的重要性以及为了防止寄生虫病对人类的影响,首次全球分子流行病学系统综述和荟萃分析,物种分布,并进行了牛结胞杆菌感染的人畜共患意义。
方法:为此,四个国际英语数据库(PubMed,Scopus,谷歌学者,和WebofScience)进行了系统搜索,直到2021年9月20日,并绘制了随机效应模型来计算总估计值及其95%置信区间(CI)。
结果:最后,来自21个国家的44篇论文有资格参加本次审查,该审查检查了8526头牛的结囊菌感染,总患病率为62.7%(95%CI53-71.5%)。全球范围内,12种肉囊虫。据报道,来自牛,包括S.Cruzi,S、人类,S.Hirsuta,S.rommeli,S.Heydorni,S.Bovifelis,S.Bovini,S.sinensis,S.gigantea,假单胞菌,S、hjorti和S.tenella。其中,S.克鲁兹(37项研究),S.hominis(22项研究)和S.hirsuta(19项研究)是3种最常见的物种,76.4%(95%CI64.8-85%),30.2%(95%CI19.3-44%)和8.7%(95%CI3.8-18.6%),分别。然而,在48.4%(95%CI27.3-70.1%)的阳性样品中未进行分子鉴定.
结论:尽管肉囊虫属物种具有人畜共患意义。,尤其是人类,牛结节虫感染的流行病学和分布尚不清楚,需要在世界各地进行更广泛的研究。
BACKGROUND: Sarcocystis
species are diverse apicomplexan parasites, though only two zoonotic
species (S. hominis and S. heydorni) circulate between cattle and humans. Due to the importance of cattle in the human food chain and to prevent the consequences of parasitosis in humans, the first global systematic
review and meta-analysis on molecular epidemiology,
species distribution, and zoonotic significance of Sarcocystis infection in cattle was performed.
METHODS: For this aim, four international English databases (PubMed, Scopus, Google Scholar, and Web of Science) were systematically searched till 20th September 2021, and random-effect models were drawn to calculate total estimates and their 95% confidence intervals (CIs).
RESULTS: Finally, 44 papers from 21 countries were qualified for this
review which examined 8526 cattle regarding Sarcocystis infection, rendering a total prevalence of 62.7% (95% CI 53-71.5%). Globally, 12 Sarcocystis spp. have been reported from cattle, including S. cruzi, S. hominis, S. hirsuta, S. rommeli, S. heydorni, S. bovifelis, S. bovini, S. sinensis, S. gigantea, S. fusiformis, S. hjorti and S. tenella. Among them, S. cruzi (37 studies), S. hominis (22 studies) and S. hirsuta (19 studies) were the 3 most common
species, with 76.4% (95% CI 64.8-85%), 30.2% (95% CI 19.3-44%) and 8.7% (95% CI 3.8-18.6%), respectively. However, molecular identification was not performed in 48.4% (95% CI 27.3-70.1%) of the positive samples.
CONCLUSIONS: Despite the zoonotic significance of Sarcocystis spp., particularly S. hominis, the epidemiology and distribution of Sarcocystis infection in cattle remains unclear and demands more extensive researches around the world.