soft tissue reconstruction

  • 文章类型: Journal Article
    背景:基于穿孔器的螺旋桨皮瓣(PPF)与游离皮瓣(FF)在创伤性小腿和足部重建中的有效性和安全性存在争议。由于避免显微外科手术等优点,PPF被认为更简单,但是担心并发症,如皮瓣充血和坏死,坚持。这项研究旨在比较PPF和FF在创伤相关的下肢远端软组织重建中的效果。
    方法:我们回顾性研究了2015年至2022年在我院因外伤而接受小腿和足部软组织重建的33例患者的38个皮瓣。比较PPF组(15例患者中有18个皮瓣)和FF组(18例患者中有20个皮瓣)之间皮瓣相关的结果和并发症。这些包括完全和部分皮瓣坏死,静脉充血,迟发性骨髓炎,和覆盖故障率,定义为由于皮瓣坏死而需要二次皮瓣。
    结果:PPF组的覆盖失败率为22%,FF组为5%,在11%的PPF组和5%的FF组中观察到完全坏死,和部分坏死在39%的PPF组和10%的FF组,表明两组之间没有显着差异。然而,与FF组的10%相比,PPF组的72%的静脉充血显著高于FF组的10%.由于来自坏死的植入物/骨折暴露,四个PPF和一个FF需要FF重建。此外,四个PPF在愈合后发展为迟发性骨髓炎,在四分之三的病例中,需要使用游离血管化骨移植物进行重建。
    结论:外伤性小腿缺损的皮瓣坏死可导致重建失败,暴露植入物或骨折,并可能导致灾难性的结果,如骨髓炎,危及肢体抢救。外科医生应该谨慎地将PPFs视为简单且无需显微外科手术的程序,考虑到创伤重建中与FF相比,并发症发生率增加。
    在当前研究过程中生成和/或分析的数据集可根据相应的作者的合理要求获得。
    BACKGROUND: The efficacy and safety of perforator-based propeller flaps (PPF) versus free flaps (FF) in traumatic lower leg and foot reconstructions are debated. PPFs are perceived as simpler due to advantages like avoiding microsurgery, but concerns about complications, such as flap congestion and necrosis, persist. This study aimed to compare outcomes of PPF and FF in trauma-related distal lower extremity soft tissue reconstruction.
    METHODS: We retrospectively studied 38 flaps in 33 patients who underwent lower leg and foot soft tissue reconstruction due to trauma at our hospital from 2015 until 2022. Flap-related outcomes and complications were compared between the PPF group (18 flaps in 15 patients) and the FF group (20 flaps in 18 patients). These included complete and partial flap necrosis, venous congestion, delayed osteomyelitis, and the coverage failure rate, defined as the need for secondary flaps due to flap necrosis.
    RESULTS: The coverage failure rate was 22% in the PPF group and 5% in the FF group, with complete necrosis observed in 11% of the PPF group and 5% of the FF group, and partial necrosis in 39% of the PPF group and 10% of the FF group, indicating no significant difference between the two groups. However, venous congestion was significantly higher in 72% of the PPF group compared to 10% of the FF group. Four PPFs and one FF required FF reconstruction due to implant/fracture exposure from necrosis. Additionally, four PPFs developed delayed osteomyelitis post-healing, requiring reconstruction using free vascularized bone graft in three out of four cases.
    CONCLUSIONS: Flap necrosis in traumatic lower-leg defects can lead to reconstructive failure, exposing implants or fractures and potentially causing catastrophic outcomes like osteomyelitis, jeopardizing limb salvage. Surgeons should be cautious about deeming PPFs as straightforward and microsurgery-free procedures, given the increased complication rates compared to FFs in traumatic reconstruction.
    UNASSIGNED: The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.
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    文章类型: Journal Article
    压力伤害(PI)是医疗保健中的一个具有挑战性的问题,在美国每年影响250万人,每年有60,000例死亡直接归因于PI。手术闭合是3期和4期PI的首选治疗方法,但并发症发生率为59%至73%,需要更少侵入性和更有效的治疗。自体异质皮肤构建体(AHSC)是一种新型的自体移植物,由健康皮肤的小型全厚度收获物制成。这项单中心回顾性队列研究旨在确定AHSC治疗顽固性4期压力伤的有效性。
    所有数据均回顾性收集。主要疗效结果是伤口完全闭合。次要疗效结果包括面积减少百分比,体积减少百分比,和覆盖暴露的结构。
    用AHSC治疗具有22个伤口的17名患者。50%的患者在平均146(SD±93)天的时间内实现了完全闭合,面积和体积的减少百分比分别为69%和81%,分别。68.2%的患者在平均106(SD±83)天的时间内实现了95%的体积减少,在平均33(SD±19)天的时间内,95%的患者完全覆盖了关键结构。AHSC治疗后,住院人数平均减少1.65人(P=.001),20.92住院天数(P<.001),和每年2.36次手术(P<0.001)。
    AHSC展示了覆盖暴露结构的能力,恢复伤口体积,并在慢性难治性4期PIs中实现持久的伤口闭合,闭合率和复发率优于目前的手术和非手术治疗。AHSC代表了重建皮瓣手术的微创替代方案,可保留未来的重建选择,同时最大程度地减少供体部位的发病率并促进患者健康状况的改善。
    UNASSIGNED: Pressure injuries (PIs) are a challenging problem in health care affecting 2.5 million people per year in the US, with 60,000 deaths directly attributed to PIs annually. Surgical closure is the treatment of choice for stage 3 and 4 PIs, but with complication rates of 59% to 73%, less invasive and more effective treatments are needed. Autologous heterogeneous skin construct (AHSC) is a novel autograft made from a small full-thickness harvest of healthy skin. This single-center retrospective cohort study sought to determine the effectiveness of AHSC in the treatment of recalcitrant stage 4 pressure injuries.
    UNASSIGNED: All data were collected retrospectively. The primary efficacy outcome was complete wound closure. Secondary efficacy outcomes included percent area reduction, percent volume reduction, and coverage of exposed structures.
    UNASSIGNED: Seventeen patients with 22 wounds were treated with AHSC. Complete closure was achieved in 50% of patients in a mean time of 146 (SD ± 93) days, and the percent area and volume reductions were 69% and 81%, respectively. A 95% volume reduction was achieved in 68.2% of patients at a mean time of 106 (SD ± 83) days, and critical structures were fully covered in 95% of patients in a mean time of 33 (SD ± 19) days. After AHSC treatment, there was a mean decrease of 1.65 hospital admissions (P = .001), 20.92 hospital days (P < .001), and 2.36 operative procedures per year (P < 0.001).
    UNASSIGNED: AHSC demonstrated the ability to cover exposed structures, restore wound volume, and achieve durable wound closure in chronic refractory stage 4 PIs with better closure and recurrence rates than current surgical and nonsurgical treatments. AHSC represents a minimally invasive alternative to reconstructive flap surgery that preserves future reconstructive options while minimizing donor-site morbidity and promoting improved patient health.
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  • 文章类型: Journal Article
    大型软组织缺损的充分伤口闭合仍然是重建外科医生的挑战。我们旨在研究组合穿支螺旋桨皮瓣(PPF)是否适合扩展重建方案。对2008年至2021年接受PPF重建手术的患者进行筛选和回顾性评估。在86名确定的患者中,69例患者接受了一个穿支螺旋桨皮瓣,17例患者接受了多皮瓣联合PPF重建。我们选择主要并发症作为我们的主要结果,并将其定义为需要额外手术的并发症。术后,27例(31.4%)患者出现严重并发症。螺旋桨瓣的尺寸,干预类型和手术时间与较高的主要并发症风险无关.然而,缺陷尺寸大于100cm2,在单个PPFs中被确定为主要并发症的重要危险因素,而在组合PPFs中则不是(OR:2.82,95%CI:1.01-8.36;p=0.05vs.OR:0.30,95%CI:0.02-3.37;p=0.32)。总之,联合PPFs被证明是一种可靠的技术,在重建躯干和下肢近端大型软组织缺损时,应优于单个PPFs。
    Sufficient wound closure of large soft tissue defects remains a challenge for reconstructive surgeons. We aimed to investigate whether combined perforator propeller flaps (PPFs) are suitable to expand reconstructive options. Patients undergoing PPF reconstruction surgery between 2008 and 2021 were screened and evaluated retrospectively. Of 86 identified patients, 69 patients received one perforator propeller flap, while 17 patients underwent combined PPF reconstruction with multiple flaps. We chose major complications as our primary outcome and defined those as complications that required additional surgery. Postoperatively, 27 patients (31.4%) suffered major complications. The propeller flap size, the type of intervention as well as the operation time were not associated with a higher risk of major complications. A defect size larger than 100 cm2, however, was identified as a significant risk factor for major complications among single PPFs but not among combined PPFs (OR: 2.82, 95% CI: 1.01-8.36; p = 0.05 vs. OR: 0.30, 95% CI: 0.02-3.37; p = 0.32). In conclusion, combined PPFs proved to be a reliable technique and should be preferred over single PPFs in the reconstruction of large soft tissue defects at the trunk and proximal lower extremity.
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  • 文章类型: Journal Article
    目的:本研究旨在回顾性分析一系列严重四肢开放性骨折(GustiloIIIb或IIIc)患者的临床资料,通过根治性矫形手术取得了令人满意的结果,从而为确定四肢严重开放性骨折的治疗方法提供参考。
    方法:连续41例四肢严重开放性骨折(GustiloIIIb或IIIc)患者的临床资料,成功进行了手术清创,固定,对2008年1月至2019年1月一期的软组织重建进行了回顾性分析.术后指标,包括感染率和结合时间,是通过定期随访和分析获得的。
    结果:患者的平均(±SD)年龄为38±16岁。共分析90例开放性骨折和严重软组织损伤。在72h内实现软组织覆盖。总感染率为14.6%(6/41)。性别和肢体错乱严重程度评分与感染相关。40例患者(1例截肢)的中位愈合时间为32周。
    结论:与以前的高级别开放性骨折两阶段矫形入路研究相比,本研究的总感染率显示出更低的趋势。感染率和愈合时间的结果与以前的研究相似。这些结果表明,单阶段根治性矫正治疗是重建严重开放性骨折的有效和可靠的选择。
    OBJECTIVE: This study aimed to retrospectively analyze clinical data of a series of patients with severe open fractures of extremities (Gustilo IIIb or IIIc), who achieved a satisfactory outcome through radical orthoplastic surgery, so as to provide a reference for determining the treatment of severe open fractures of extremities.
    METHODS: The clinical data of 41 consecutive patients with severe open fracture (Gustilo IIIb or IIIc) of the limb, who underwent successful surgical debridement, fixation, and soft tissue reconstruction in one stage between January 2008 and January 2019, were retrospectively reviewed. Postoperative indicators, including infection rate and union time, were acquired by a regular follow-up and analyzed.
    RESULTS: The mean (±SD) age of the patients was 38 ± 16 years. A total of 90 open fractures and severe soft tissue damages were analyzed. The soft tissue cover was achieved within 72 h. The overall rate of infection was 14.6% (6/41). Sex and the Mangled Extremity Severity Score were associated with infection. The median union time of 40 patients (one amputation) was 32 weeks.
    CONCLUSIONS: The overall rate of infection exhibited a lower tendency in this study compared with previous studies on high-grade open fractures following a two-stage orthopedic approach. The consequence of infection rate and union time was similar to that in previous studies. These results indicated that the single-stage radical orthoplastic treatment was an effective and reliable option for reconstructing severe open fractures.
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  • 文章类型: Journal Article
    Retrospectively analyze the reconstruction methods and surgical outcomes of patients with middle and lower face soft tissue defects treated at our hospital over the past 10 years. 200 patients with middle and lower face soft tissue defects were surgically reconstructed at our hospital. Medical charts were retrospectively reviewed and analyzed to abstract the pertinent information. The lesion was mainly at the eyelid, lips, chin and nasal-cheek region. There were 41 (63.08 %) men and 24 (36.92 %) women. In our study, male to female ratio = 1.7:1. We used direct closure for night patients, local flap for 141 patients, free flap for 38 patients, combined flap for 12 patients involving extensive mid face and lower face defects. Most patients had their tumor resected and reconstructed in single stage procedure mostly with local advancement flap, and no flap failure was presented post-operatively. Middle and lower face soft tissue defects can be successfully treated with local flap in a single stage approach and step-by-step approach.
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