signal processing

信号处理
  • 文章类型: Journal Article
    目标:调查有助于有效管理年龄相关性听力损失(ARHL)康复的因素。方法:遵循PRISMA指南进行系统评价。该方案在PROSPERO(CRD42022374811)中注册。文章是通过Scopus的系统搜索确定的,PubMed,WebofScience,以及2024年5月的Cochrane数据库。仅包括2005年1月至2024年5月之间发表的文章。由两名独立研究人员评估研究的资格,并使用Crowe关键评估工具v1.4(CCAT)进行评估。结果:在确定的278篇文章中,54人被包括在内。三个因素解释了HA的有效使用。首先,助听器信号处理,具有定向麦克风和降噪功能,提高了用户的舒适度和对噪声的理解。第二,有助听器配件,以NAL处方规则为黄金标准,和双边,用于空间定位和噪声理解的高级HA性能。第三,有一种以病人为中心的方法,使用患者相关结果测量(PROM),问卷,咨询,并定期随访,让患者参与治疗康复。结论:由于听力学结果的可变性,在声学参数上达成共识具有挑战性。让病人参与康复,满足他们的需求和期望,提供个性化护理至关重要。
    Objectives: Investigate factors contributing to the effective management of age-related hearing loss (ARHL) rehabilitation. Methods: A systematic review was conducted following PRISMA guidelines. The protocol was registered in PROSPERO (CRD42022374811). Articles were identified through systematic searches in the Scopus, PubMed, Web of Science, and Cochrane databases in May 2024. Only articles published between January 2005 and May 2024 were included. Studies were assessed for eligibility by two independent researchers and evaluated using the Crowe Critical Appraisal Tool v1.4 (CCAT). Results: Of the 278 articles identified, 54 were included. Three factors explain effective HA use. First, hearing aid signal processing, with directional microphones and noise reduction, improves user comfort and understanding regarding noise. Second, there is hearing aid fitting, with the NAL prescription rules as the gold standard, and bilateral, high-level HA performance for spatial localization and noise comprehension. Third, there is a patient-centered approach, using patient-related outcome measures (PROMs), questionnaires, counseling, and regular follow-up to involve patients in their therapeutic rehabilitation. Conclusions: Reaching a consensus on acoustic parameters is challenging due to variability in audiological results. Involving patients in their rehabilitation, addressing their needs and expectations, and offering individualized care are crucial.
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  • 文章类型: Journal Article
    胃电图(EGG)是一种非侵入性方法,具有很高的诊断潜力,可在临床实践中预防胃肠病变。在这项研究中,对测量系统的审查,程序,并介绍了胃电图的分析方法。对历史和当前文献进行了批判性审查,专注于电极放置,测量仪器,测量程序,和非侵入性测量的胃的电活动的过滤和分析的时频域方法。因此,本研究综述了129篇主要针对实验饮食的相关文章。Scopus,PubMed,和WebofScience数据库被用来搜索英语文章,根据具体查询并使用PRISMA方法。自从100年前阿尔瓦雷斯教授首次测量以来,胃电图的研究课题一直在不断普及,如今,有许多研究人员和公司对EGG感兴趣。测量设备和程序仍在商业和研究环境中开发。有很多可变的电极布局,从用于动态测量的最小数量的电极到用于空间测量的非常高数量的电极。大多数作者在他们的研究中使用解剖学近似布局,双极连接中的两个++有源电极和采样速率为2或4Hz的商业胃电图仪。测试对象通常是健康的成年人,饮食受到控制。然而,评估方法的发展速度较慢,通常只根据主频对信号进行分类。主要综述的贡献包括许多作者开发的胃电图测量系统和程序的频谱概述,但是还没有明确的医疗标准。因此,在临床实践中不可能使用这种方法进行客观诊断。
    https://www.prisma-statement.org/.
    Electrogastrography (EGG) is a non-invasive method with high diagnostic potential for the prevention of gastroenterological pathologies in clinical practice. In this study, a review of the measurement systems, procedures, and methods of analysis used in electrogastrography is presented. A critical review of historical and current literature is conducted, focusing on electrode placement, measurement apparatus, measurement procedures, and time-frequency domain methods of filtration and analysis of the non-invasively measured electrical activity of the stomach. As a result, 129 relevant articles with primary aim on experimental diet were reviewed in this study. Scopus, PubMed, and Web of Science databases were used to search for articles in English language, according to the specific query and using the PRISMA method. The research topic of electrogastrography has been continuously growing in popularity since the first measurement by professor Alvarez 100 years ago, and there are many researchers and companies interested in EGG nowadays. Measurement apparatus and procedures are still being developed in both commercial and research settings. There are plenty variable electrode layouts, ranging from minimal numbers of electrodes for ambulatory measurements to very high numbers of electrodes for spatial measurements. Most authors used in their research anatomically approximated layout with two++ active electrodes in bipolar connection and commercial electrogastrograph with sampling rate of 2 or 4 Hz. Test subjects were usually healthy adults and diet was controlled. However, evaluation methods are being developed at a slower pace, and usually the signals are classified only based on dominant frequency. The main review contributions include the overview of spectrum of measurement systems and procedures for electrogastrography developed by many authors, but a firm medical standard has not yet been defined. Therefore, it is not possible to use this method in clinical practice for objective diagnosis.
    UNASSIGNED: https://www.prisma-statement.org/.
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  • 文章类型: Journal Article
    桥梁是交通网络的关键组成部分,他们的状况对社会福祉有影响,经济,和环境。检查和维护的自动化需求使结构健康监测(SHM)系统成为评估桥梁安全/健康的关键研究支柱。随着下一代智能和移动技术的兴起,过去十年带来了创新桥梁SHM应用的繁荣。在这个方向上的一个关键进步是智能手机作为SHM设备的感官使用。这篇重点综述报告了由智能手机传感器技术支持的桥梁SHM的最新进展,并提供了桥梁SHM应用的案例研究。该审查包括基于模型和数据驱动的SHM前景,利用智能手机作为传感和采集门户,并在技术领域和移动性水平方面传达了三个不同的信息:(i)基于振动的动态识别和损坏检测方法;(ii)由基于计算机视觉的测量能力提供的变形和状态监测;(iii)驶过或步行桥监测方法,以及具有非常规/新兴技术特征和新研究领域的各种SHM应用。这项审查旨在汇集桥梁工程,SHM,和传感器技术受众在基于智能手机的SHM主题中观察到了长达十年的多学科经验,并提供了涉及各种移动性水平的示例案例。
    Bridges are critical components of transportation networks, and their conditions have effects on societal well-being, the economy, and the environment. Automation needs in inspections and maintenance have made structural health monitoring (SHM) systems a key research pillar to assess bridge safety/health. The last decade brought a boom in innovative bridge SHM applications with the rise in next-generation smart and mobile technologies. A key advancement within this direction is smartphones with their sensory usage as SHM devices. This focused review reports recent advances in bridge SHM backed by smartphone sensor technologies and provides case studies on bridge SHM applications. The review includes model-based and data-driven SHM prospects utilizing smartphones as the sensing and acquisition portal and conveys three distinct messages in terms of the technological domain and level of mobility: (i) vibration-based dynamic identification and damage-detection approaches; (ii) deformation and condition monitoring empowered by computer vision-based measurement capabilities; (iii) drive-by or pedestrianized bridge monitoring approaches, and miscellaneous SHM applications with unconventional/emerging technological features and new research domains. The review is intended to bring together bridge engineering, SHM, and sensor technology audiences with decade-long multidisciplinary experience observed within the smartphone-based SHM theme and presents exemplary cases referring to a variety of levels of mobility.
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  • 文章类型: Journal Article
    减少化石燃料的使用,清洁能源供应,和可靠性都是集成分布式能源(DER)与电网(UG)的主要好处。然而,这种整合有困难,最值得注意的是意外孤岛,使工人和设备的安全处于危险之中。孤岛检测方法(IDM)在解决此问题中起着至关重要的作用。在这项工作中,所有IDM都得到了彻底的评估,将它们分为两类:依赖分布式发电(DG)侧监控的本地方法和利用通信基础设施的远程方法。该研究提供了比较评估,以帮助选择最有效和适用的IDM,支持明智的决策,以确保配电网络中分布式能源系统的安全可靠运行。IDM是根据NDZ结果进行评估的,检测持续时间,电能质量影响,多DG操作,适用性,X/R比依赖,和高效运作。
    Reduction of fossil fuel usage, clean energy supply, and dependability are all major benefits of integrating distributed energy resources (DER) with electrical utility grid (UG). Nevertheless, there are difficulties with this integration, most notably accidental islanding that puts worker and equipment safety at risk. Islanding detection methods (IDMs) play a critical role in resolving this problem. All IDMs are thoroughly evaluated in this work, which divides them into two categories: local approaches that rely on distributed generation (DG) side monitoring and remote approaches that make use of communication infrastructure. The study offers a comparative evaluation to help choose the most efficient and applicable IDM, supporting well-informed decision-making for the safe and dependable operation of distributed energy systems within electrical distribution networks. IDMs are evaluated based on NDZ outcomes, detection duration, power quality impact, multi-DG operation, suitability, X/R ratio reliance, and efficient functioning.
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  • 文章类型: Journal Article
    背景:分娩期间的子宫收缩会限制孕妇的血流和给发育中的婴儿的氧气输送,导致短暂的缺氧.虽然大多数婴儿在生理上适合承受这种产时缺氧,那些暴露于严重缺氧或生理储备不足的人可能会在分娩期间遭受神经损伤或死亡。通过检测胎儿心率(FHR)模式的变化,开发了心脏描记术(CTG)监测以识别有缺氧风险的婴儿。CTG监测在产时护理中广泛用于检测胎儿缺氧,但由于CTG异常的阳性预测值(PPV)相对较差,以及CTG解释中观察者之间和观察者之间的显着差异,临床应用受到限制。临床风险和人为因素可能会影响CTG解释的质量。CTG痕迹的错误分类可能导致治疗不足(有胎儿受伤或死亡的风险)或过度治疗(可能包括不必要的手术干预措施,使母亲和婴儿都面临并发症的风险)。自2000年初以来,机器学习(ML)已被应用于此问题,并且已显示出比单独对CTG进行视觉解释更准确地预测胎儿缺氧的潜力。为了考虑如何将这些工具翻译为临床实践,我们对已经应用于CTG分类的ML技术进行了回顾,并确定了需要进行调查的研究空白,以推进临床实施.
    方法:我们使用已识别的关键字在数据库中搜索PubMed上的相关出版物,EMBASE和IEEEXplore。我们使用首选报告项目进行系统评价和Meta分析(PRISMA-ScR)。Title,根据纳入标准对摘要和全文进行筛选。
    结果:我们纳入了36项使用信号处理和ML技术对CTG进行分类的研究。大多数研究使用开放获取的CTG数据库,并主要使用胎儿代谢性酸中毒作为pH值变化的缺氧基准。使用各种方法处理和提取CTG信号,并使用几种ML算法对CTG进行分类。我们确定了对使用不同pH水平作为CTG分类基准的实用性的重大关注。此外,研究需要更一般化,因为大多数人使用相同的数据库,而ML研究的受试者数量较少。
    结论:ML研究证明了CTG预测胎儿缺氧的潜力。然而,更多样化的数据集,未来的临床实施需要缺氧基准的标准化以及算法和特征的增强。
    BACKGROUND: Uterine contractions during labour constrict maternal blood flow and oxygen delivery to the developing baby, causing transient hypoxia. While most babies are physiologically adapted to withstand such intrapartum hypoxia, those exposed to severe hypoxia or with poor physiological reserves may experience neurological injury or death during labour. Cardiotocography (CTG) monitoring was developed to identify babies at risk of hypoxia by detecting changes in fetal heart rate (FHR) patterns. CTG monitoring is in widespread use in intrapartum care for the detection of fetal hypoxia, but the clinical utility is limited by a relatively poor positive predictive value (PPV) of an abnormal CTG and significant inter and intra observer variability in CTG interpretation. Clinical risk and human factors may impact the quality of CTG interpretation. Misclassification of CTG traces may lead to both under-treatment (with the risk of fetal injury or death) or over-treatment (which may include unnecessary operative interventions that put both mother and baby at risk of complications). Machine learning (ML) has been applied to this problem since early 2000 and has shown potential to predict fetal hypoxia more accurately than visual interpretation of CTG alone. To consider how these tools might be translated for clinical practice, we conducted a review of ML techniques already applied to CTG classification and identified research gaps requiring investigation in order to progress towards clinical implementation.
    METHODS: We used identified keywords to search databases for relevant publications on PubMed, EMBASE and IEEE Xplore. We used Preferred Reporting Items for Systematic Review and Meta-Analysis for Scoping Reviews (PRISMA-ScR). Title, abstract and full text were screened according to the inclusion criteria.
    RESULTS: We included 36 studies that used signal processing and ML techniques to classify CTG. Most studies used an open-access CTG database and predominantly used fetal metabolic acidosis as the benchmark for hypoxia with varying pH levels. Various methods were used to process and extract CTG signals and several ML algorithms were used to classify CTG. We identified significant concerns over the practicality of using varying pH levels as the CTG classification benchmark. Furthermore, studies needed to be more generalised as most used the same database with a low number of subjects for an ML study.
    CONCLUSIONS: ML studies demonstrate potential in predicting fetal hypoxia from CTG. However, more diverse datasets, standardisation of hypoxia benchmarks and enhancement of algorithms and features are needed for future clinical implementation.
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  • 文章类型: Systematic Review
    呼吸系统疾病是一个巨大的全球负担,需要有效的诊断方法进行及时干预。基于音频的数字生物标志物,声学,和上下呼吸系统发出的声音,以及声音,已成为呼吸功能的有价值指标。机器学习(ML)算法的最新进展为通过分析和处理此类基于音频的生物标志物来识别和诊断呼吸系统疾病提供了有希望的途径。越来越多的研究采用ML技术从音频生物标志物中提取有意义的信息。除了疾病识别,这些研究探索了不同的方面,例如在环境噪声中识别咳嗽声音,分析呼吸音,以检测呼吸道症状,如喘息和裂纹,以及语音/语音的分析,用于评估人类语音异常。为了提供更深入的分析,这篇综述审查了75项相关的音频分析研究,涉及三个不同的领域,涉及呼吸道疾病的症状:(a)咳嗽检测,(b)下呼吸道症状识别,和(c)来自语音和语音的诊断。此外,提供了该领域常用的公共可用数据集。据观察,研究趋势受到大流行的影响,随着对COVID-19诊断的研究激增,移动数据采集,和远程诊断系统。
    Respiratory diseases represent a significant global burden, necessitating efficient diagnostic methods for timely intervention. Digital biomarkers based on audio, acoustics, and sound from the upper and lower respiratory system, as well as the voice, have emerged as valuable indicators of respiratory functionality. Recent advancements in machine learning (ML) algorithms offer promising avenues for the identification and diagnosis of respiratory diseases through the analysis and processing of such audio-based biomarkers. An ever-increasing number of studies employ ML techniques to extract meaningful information from audio biomarkers. Beyond disease identification, these studies explore diverse aspects such as the recognition of cough sounds amidst environmental noise, the analysis of respiratory sounds to detect respiratory symptoms like wheezes and crackles, as well as the analysis of the voice/speech for the evaluation of human voice abnormalities. To provide a more in-depth analysis, this review examines 75 relevant audio analysis studies across three distinct areas of concern based on respiratory diseases\' symptoms: (a) cough detection, (b) lower respiratory symptoms identification, and (c) diagnostics from the voice and speech. Furthermore, publicly available datasets commonly utilized in this domain are presented. It is observed that research trends are influenced by the pandemic, with a surge in studies on COVID-19 diagnosis, mobile data acquisition, and remote diagnosis systems.
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  • 文章类型: Journal Article
    变化点指示在一些时间点数据流中的统计特性的显著变化。有效地检测变化点对于我们了解具有通用参数变化模式的现代数据流中的底层数据生成机制至关重要。然而,在嘈杂数据中定位多个变化点成为一个极具挑战性的问题。尽管贝叶斯信息准则已被证明是在渐近意义上选择多个变化点的有效方法,它的有限样本性能可能是有缺陷的。在这篇文章中,我们回顾了一系列基于信息标准的多变化点检测方法,包括Akaike信息标准,贝叶斯信息准则,最小描述长度,以及它们的变体,强调它们的实际应用。进行模拟研究,以调查不同信息标准在检测多个变化点时的实际性能,并为从业人员提供可能的模型错误规范。以风力发电机的SCADA信号为例进行了研究,以演示不同信息标准的实际变化点检测功率。最后,为今后的研究工作提出了多变点检测的发展和应用中的一些关键挑战。
    Change points indicate significant shifts in the statistical properties in data streams at some time points. Detecting change points efficiently and effectively are essential for us to understand the underlying data-generating mechanism in modern data streams with versatile parameter-varying patterns. However, it becomes a highly challenging problem to locate multiple change points in the noisy data. Although the Bayesian information criterion has been proven to be an effective way of selecting multiple change points in an asymptotical sense, its finite sample performance could be deficient. In this article, we have reviewed a list of information criterion-based methods for multiple change point detection, including Akaike information criterion, Bayesian information criterion, minimum description length, and their variants, with the emphasis on their practical applications. Simulation studies are conducted to investigate the actual performance of different information criteria in detecting multiple change points with possible model mis-specification for the practitioners. A case study on the SCADA signals of wind turbines is conducted to demonstrate the actual change point detection power of different information criteria. Finally, some key challenges in the development and application of multiple change point detection are presented for future research work.
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  • 文章类型: Journal Article
    脑电图(EEG)和眼电图(EOG)是电生理监测的方法,在神经科学中具有潜在的卓有成效的应用,临床探索,航空工业,和其他部门。这些方法通常是评估大脑振荡和眼球运动的最直接方法,因为他们使用标准的实验室或移动技术。这篇综述描述了EEG和EOG系统的潜力以及这些方法在航空学中的应用。例如,EEG和EOG信号可用于设计脑机接口(BCI)和解释大脑活动,例如监测飞行员的精神状态以确定他们的工作量。这次审查的主要目标是,(i)对EEG和EOG的基础知识及其在航空学中的应用进行深入的文献回顾;(ii)探索过去十年中EEG-EOG组合研究的方法和趋势;(iii)为初学者和专家在实验室以外的环境中应用这些方法时提供方法学指南,特别关注人为因素和航空。这项研究使用了来自科学的数据库,临床,和神经工程领域。本文首先介绍了EEG和EOG的特点及其在航空学中的应用,对相关文献进行了大量回顾,从早期到最近的研究。然后,我们建立了一个新的分类模型,其中包括2010年1月至2020年3月在同行评审的科学期刊和会议上发表的150篇合并EEG-EOG论文。对每项研究的几个数据元素进行了审查(例如,预处理,提取的特征和性能指标),然后对其进行了检查,以揭示航空学的趋势,并从这一重要的文献中总结出有趣的方法。最后,审查考虑了这些方法的优点和局限性以及未来的挑战。
    Electro-encephalography (EEG) and electro-oculography (EOG) are methods of electrophysiological monitoring that have potentially fruitful applications in neuroscience, clinical exploration, the aeronautical industry, and other sectors. These methods are often the most straightforward way of evaluating brain oscillations and eye movements, as they use standard laboratory or mobile techniques. This review describes the potential of EEG and EOG systems and the application of these methods in aeronautics. For example, EEG and EOG signals can be used to design brain-computer interfaces (BCI) and to interpret brain activity, such as monitoring the mental state of a pilot in determining their workload. The main objectives of this review are to, (i) offer an in-depth review of literature on the basics of EEG and EOG and their application in aeronautics; (ii) to explore the methodology and trends of research in combined EEG-EOG studies over the last decade; and (iii) to provide methodological guidelines for beginners and experts when applying these methods in environments outside the laboratory, with a particular focus on human factors and aeronautics. The study used databases from scientific, clinical, and neural engineering fields. The review first introduces the characteristics and the application of both EEG and EOG in aeronautics, undertaking a large review of relevant literature, from early to more recent studies. We then built a novel taxonomy model that includes 150 combined EEG-EOG papers published in peer-reviewed scientific journals and conferences from January 2010 to March 2020. Several data elements were reviewed for each study (e.g., pre-processing, extracted features and performance metrics), which were then examined to uncover trends in aeronautics and summarize interesting methods from this important body of literature. Finally, the review considers the advantages and limitations of these methods as well as future challenges.
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  • 文章类型: Journal Article
    不久前,听觉设备为生物传感铺平了道路,健身,和医疗保健监测。如今的智能耳塞不仅产生声音,而且还监测生命体征。可靠地确定心血管和肺系统信息可以探索使用听觉器进行生理监测。最近的研究表明,光电体积描记(PPG)信号不仅包含有关氧饱和度(SPO2)的详细信息,而且还携带更多的生理信息,包括脉搏率,呼吸频率,血压,和动脉相关的信息。在研究环境中,对来自耳朵的PPG信号的分析已被证明是可靠且准确的。(1)背景:本综合综述探讨了有关入耳式PPG信号及其应用的现有文献。本文旨在确定耳内PPG的当前技术和用途以及耳内PPG在生理监测中的现有证据。本文还分析了入耳式(PPG)测量的配置和原理,波形特征,加工技术,和特征提取特征。(2)方法:我们进行了全面的搜索,以发现直到2022年12月发表的相关入耳式PPG文章。以下电子数据库:电气和电子工程师协会(IEEE),ScienceDirect,Scopus,WebofScience,和PubMed用于进行研究,以解决生理监测中耳内PPG的证据。(3)结果:确定了14项研究,但完成了9项研究。八项研究是关于可听PPG的不同原理和配置,8项研究涉及耳内生理监测中的处理技术和特征提取及其证据。我们还强调了在生理监测中使用入耳式PPG的局限性和挑战。(4)结论:现有证据揭示了入耳式PPG在生理监测中的未来。我们还分析了入耳式PPG在处理信号时将面临的潜在限制和挑战。
    Not long ago, hearables paved the way for biosensing, fitness, and healthcare monitoring. Smart earbuds today are not only producing sound but also monitoring vital signs. Reliable determination of cardiovascular and pulmonary system information can explore the use of hearables for physiological monitoring. Recent research shows that photoplethysmography (PPG) signals not only contain details on oxygen saturation level (SPO2) but also carry more physiological information including pulse rate, respiration rate, blood pressure, and arterial-related information. The analysis of the PPG signal from the ear has proven to be reliable and accurate in the research setting. (1) Background: The present integrative review explores the existing literature on an in-ear PPG signal and its application. This review aims to identify the current technology and usage of in-ear PPG and existing evidence on in-ear PPG in physiological monitoring. This review also analyzes in-ear (PPG) measurement configuration and principle, waveform characteristics, processing technology, and feature extraction characteristics. (2) Methods: We performed a comprehensive search to discover relevant in-ear PPG articles published until December 2022. The following electronic databases: Institute of Electrical and Electronics Engineers (IEEE), ScienceDirect, Scopus, Web of Science, and PubMed were utilized to conduct the studies addressing the evidence of in-ear PPG in physiological monitoring. (3) Results: Fourteen studies were identified but nine studies were finalized. Eight studies were on different principles and configurations of hearable PPG, and eight studies were on processing technology and feature extraction and its evidence in in-ear physiological monitoring. We also highlighted the limitations and challenges of using in-ear PPG in physiological monitoring. (4) Conclusions: The available evidence has revealed the future of in-ear PPG in physiological monitoring. We have also analyzed the potential limitation and challenges that in-ear PPG will face in processing the signal.
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  • 文章类型: Journal Article
    脑电图(EEG)信号是一种无创、复杂的信号,在生物医学领域有着广泛的应用。包括睡眠和脑机接口.鉴于其复杂性,研究人员提出了几种先进的预处理和特征提取方法来分析脑电信号。在这项研究中,我们分析了大量与EEG信号处理相关的文章的综合综述。我们搜索了主要的科学和工程数据库,并总结了我们的发现结果。我们的调查涵盖了EEG信号处理的整个过程,从采集和预处理(去噪)到特征提取,分类,和应用。我们将详细讨论和比较用于EEG信号处理的各种方法和技术。此外,我们确定了这些技术的当前局限性,并分析了它们未来的发展趋势。最后,我们为脑电信号处理领域的未来研究提供了一些建议。
    The electroencephalography (EEG) signal is a noninvasive and complex signal that has numerous applications in biomedical fields, including sleep and the brain-computer interface. Given its complexity, researchers have proposed several advanced preprocessing and feature extraction methods to analyze EEG signals. In this study, we analyze a comprehensive review of numerous articles related to EEG signal processing. We searched the major scientific and engineering databases and summarized the results of our findings. Our survey encompassed the entire process of EEG signal processing, from acquisition and pretreatment (denoising) to feature extraction, classification, and application. We present a detailed discussion and comparison of various methods and techniques used for EEG signal processing. Additionally, we identify the current limitations of these techniques and analyze their future development trends. We conclude by offering some suggestions for future research in the field of EEG signal processing.
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