UNASSIGNED: Obesity causes many health problems and affects the quality and duration of life negatively. We aimed to investigate the relationship between sex steroids, insulin resistance and body compositions in obese women.
UNASSIGNED: This study was carried out on a sample of 150 premenopausal women who were referred to the Outpatient Clinic of Family Medicine between 2014-2015. A survey about their socio-demographic characteristics was carried out, and anthropometric parameters were measured. LDL-C, HDL-C, total cholesterol, triglyceride, glucose, insulin, sex hormone binding globulin (SHBG), estradiol, dehydroepiandrosterone sulfate (DHEA-S), total/free testosterone levels were measured in the blood. Body compositions were assessed with a bioelectrical impedance device. For insulin resistance, Homeostasis Model Assessment (HOMA-IR) was calculated.
UNASSIGNED: In our study, a significant association was found between high glucose, total cholesterol, LDL-C, TG, insulin, insulin resistance and low HDL-C, SHBG, DHEA-S levels with obesity (p<0.05). There was no statistically significant relationship between estradiol, total/free testosterone and obesity (p>0.05).
UNASSIGNED: In our study, high glucose, total cholesterol, LDL-c, TG, insulin, insulin resistance and low HDL-C, SHBG, DHEA-S levels were associated with obesity. This relationship leads to many diseases, especially diabetes mellitus and cardiovascular disease. Therefore, obesity is a disease that needs to be monitored closely, frequently and treated properly.
UNASSIGNED: Gojaznost izaziva mnoge zdravstvene probleme i negativno utiče na kvalitet života i životni vek. Cilj nam je bio da istražimo vezu između polnih steroida, insulinske rezistencije i telesne kompozicije kod gojaznih žena.
UNASSIGNED: Ova studija je sprovedena na uzorku od 150 žena u perimenopauzi koje su posetile ambulantu porodične medicine u periodu 2014-2015. Primenjeno je istraživanje o njihovim socio-demografskim karakteristikama i izmereni su antropometrijski parametri. Iz krvi su izmereni LDL-C, HDL-C, ukupni holesterol, trigliceridi, glukoza, insulin, globulin koji vezuje polni hormon (SHBG), estradiol, dehidroepiandrosteron sulfat (DHEA-S), i nivoi ukupnog/slobodnog testosterona. Telesne kompozicije su procenjene pomoću uređaja sa bioelektričnom impedansom. Za rezistenciju na insulin, izračunat je Homa model (HOMA-IR, Homeostasis Model Assessment).
UNASSIGNED: U našoj studiji je pronađena značajna povezanost između visoke glukoze, ukupnog holesterola, LDL-C, TG, insulina, rezistencije na insulin i niskog nivoa HDL-C, SHBG, DHEA-S i gojaznosti (p<0,05). Nije bilo statistički značajne veze između estradiola, ukupnog/slobodnog testosterona i gojaznosti (p>0,05).
UNASSIGNED: Naša studija je ukazala da su sledeći faktori bili povezani sa gojaznošću: visoka glukoza, ukupni holesterol, LDL-C, TG, insulin, insulinska rezistencija i niski nivoi HDLC, SHBG, DHEA-S. Ovaj odnos dovodi do mnogih bolesti, posebno dijabetes melitusa i kardiovaskularnih bolesti. Dakle, gojaznost je bolest koju treba pažljivo pratiti i redovno tretirati na odgovarajući način.