sebaceous gland

皮脂腺
  • 文章类型: Journal Article
    皮脂瘤是一种罕见的良性肿瘤,起源于皮肤皮脂腺。皮球瘤通常发生在头部和颈部,但很少发生在耳朵上。我们介绍了一名78岁的女性患者,其左耳有两年突出的肿块病史。体格检查显示,左耳螺旋的小腿有一个界限清楚的斑块。进行了广泛的局部切除活检,并对肿块进行组织病理学评估。虽然肿块显示细胞学发现表明皮脂腺瘤,它还在结构和免疫组织化学上呈现恶性特征。基于这些发现,该肿瘤被认为是交界性恶性肿瘤的皮瘤。
    在线版本包含补充材料,可在10.1007/s12070-023-03552-4获得。
    Sebaceoma is a rare benign tumor arising from the sebaceous gland of the skin. Sebaceoma often occurs on the head and neck but rarely on the ears. We present the case of a 78-year-old female patient with a two-year history of a protruding mass in her left ear. Physical examination revealed a well-circumscribed plaque in the crus of the helix of the left ear. A wide local excisional biopsy was taken, and the mass was subjected to histopathologic assessment. While the mass showed cytological findings indicating sebaceoma, it also presented malignant features architecturally and immunohistochemically. Based on these findings, the tumor was regarded as a sebaceoma of borderline malignancy.
    UNASSIGNED: The online version contains supplementary material available at 10.1007/s12070-023-03552-4.
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  • 文章类型: Case Reports
    毛眼癌(TC)是一种罕见的具有柱状分化的皮肤恶性肿瘤。TC与其他恶性毛囊肿瘤一起存在,仅占所有附件癌的1%。TC通常发生在老年人阳光照射的皮肤上,然而,它可以发生在任何年龄。我们报告了一例54岁的女性,表现为枕部囊肿增加的毛囊囊肿癌。组织学检查证实了诊断,并进行了大切除。尽管对TC的管理缺乏明确的共识,在没有转移性病变的情况下,具有足够切缘的手术切除似乎是安全的。然而,在第二次本地化的情况下,化疗可以开始,但同样,在这种情况下,在适当的协议上没有共识。
    Trichilemmal carcinoma (TC) is a rare skin malignant tumor with pillar differentiation. TC presents along with other malignant hair follicle tumors and accounts for only 1% of all adnexal carcinomas. TC usually occurs on sun-exposed skin in elderly people, nevertheless, it can occur at any age. We report a case of trichilemmal cyst carcinoma in a 54-year-old woman presenting with an increasing occipital cyst. A histological examination confirmed the diagnosis and a large excision was performed. Despite the absence of a well-defined consensus on the management of TC, surgical excision with adequate margins seems to be safe in the absence of metastatic lesions. However, in the case of second localization, chemotherapy could be initiated, but again, in this case, no consensus on the appropriate protocols exists.
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  • 文章类型: Case Reports
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  • 文章类型: Case Reports
    UNASSIGNED: Steatocystoma multiplex is a benign skin disorder originating from the sebaceous and nevoid ducts. Commonly classified under hamartomas, they are distributed over the trunk, neck, axillae, and groin.
    UNASSIGNED: A 28-year-old male patient complained of multiple, asymptomatic skin-colored nodules over the face of 10-year duration. Clinical examination confirmed the historic findings of nontender, polysized, flesh-colored papules and nodules over the said distribution.
    UNASSIGNED: On histopathology, a cyst was noted in the mid-dermis, lined by stratified squamous, agranular epithelium, which contained degenerated keratin. Nonpolarized dermoscopy showed a structureless, cream-colored area, and polarized dermoscopy revealed a distinctive, well-circumscribed, yellowish hue which was superimposed over the facial pseudoreticular pigmentary pattern. The findings were compatible with steatocystoma multiplex, and the patient was taken up for radiofrequency ablation.
    UNASSIGNED: Herein, we report a rare variant of steatocystoma multiplex limited to the face and scalp subjected to dermatoscopy and characteristic histological correlation. To the best of our knowledge and following a literature search, dermoscopic features of this condition have not been reported thus far.
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  • 文章类型: Journal Article
    BACKGROUND: Lymphoepithelial cyst (LEC) of the pancreas is a rare benign tumor. LEC with sebaceous glands of the pancreas is extremely rare, and its histogenesis remains unclear.
    METHODS: We present a 66-year-old man with an incidental finding of a cystic lesion at the neck of the pancreas. Pancreatic juice cytology results and elevated serum carbohydrate antigen 19-9 and Dupan-2 levels indicated that the cyst was a potential adenocarcinoma. Therefore, a pancreaticoduodenectomy was performed. Macroscopically, the tumor was a unilocular cyst with a thin transparent wall, filled with soft yellow material. Pathological findings showed that the cyst was lined with squamous epithelium, accompanied by dense lymphoid tissue with scattered germinal centers. There were no hair follicles, but sebaceous glands were present in the lymphoid tissue just beneath the squamous epithelium. Therefore, the histopathological diagnosis was an LEC with sebaceous glands of the pancreas. Furthermore, the squamous epithelium surrounding the cyst was pathologically continuous with the tubular structure, indicating that the tubular structure transitioned into the squamous epithelium.
    CONCLUSIONS: We report an extremely rare case of LEC with sebaceous glands of the pancreas. Moreover, the pathological findings, which showed that the tubular structure transitioned into the squamous epithelium, suggested that this was squamous metaplasia. In order to investigate the histogenesis of LEC of the pancreas, the pathological findings must be evaluated.
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