robotic surgical procedures

机器人外科手术
  • 文章类型: English Abstract
    The use of robotic operating systems is an advancement of intelligent precision, minimally invasive surgery. It has been used in the field of thyroid surgery with satisfactory results. Robotic surgery system assisted thyroid and parathyroid surgical expert consensus(2016) as played an important role in the standardization and clinical popularization of robotic surgical system-assisted thyroid and parathyroid surgery. With the deepening of clinical practice, updates in minimally invasive concept, the replacement of robotic platforms and the continuous improvement of technology, robotic thyroid and parathyroid surgery has been further developed. Notably, it has made substantial progress in expanding indications and the training of robotic surgeons and teams. Based on the 2016 Chinese expert consensus, combined with recent related articles and clinical studies, the Clinical Practice Guideline for Robotic Surgical System-Assisted Thyroid and Parathyroid Surgery (2024 edition) was formed. The surgical team training, indications, preoperative evaluation, patient position and space establishment, thyroidectomy procedures, neck lymph node dissection skills were summarized and recommended. Furthermore, reasonable suggestions on reoperation, parathyroid surgery and management of postoperative complications were also put forward, aiming to better guide clinical practice.
    机器人外科是智能精准微创外科发展的成果,应用于甲状腺外科领域,取得了良好临床效果。我国《机器人手术系统辅助甲状腺和甲状旁腺手术专家共识(2016版)》的发布对机器人辅助甲状腺和甲状旁腺手术的规范化开展与临床推广起到了重要作用。随着临床实践的深入、微创理念的更新、机器人平台更新换代和技术不断改进,机器人甲状腺和甲状旁腺外科得到了进一步发展,尤其在适应证拓展、机器人外科医师培训和团队建设方面有了较大进步。在2016版专家共识的基础上,结合近年发表的相关论著及临床研究,专家组撰写了《机器人手术系统辅助甲状腺和甲状旁腺手术临床实践指南(2024版)》,从手术团队培养、手术适应证、术前评估、患者体位和空间建立、甲状腺腺叶切除步骤、颈部淋巴结清扫技巧等方面进行了总结推荐,并对再次手术、甲状旁腺手术及术后并发症的防治等方面提出了合理建议,以期更好地指导临床实践。.
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  • 文章类型: Journal Article
    总的来说,在过去的20年中,已经观察到口咽癌的趋势是经口切除术(与经典的开放方法相反),颈淋巴结清扫术和辅助放射(化学)治疗。经口外科手术技术(TOS),包括经口激光显微手术(TLM)和经口机器人手术(TORS)已经在与传统手术或原发性放化疗的回顾性比较中传播,具有良好后期功能效果的微创手术。大多数不受控制的回顾性分析的荟萃分析表明,与开放手术相比,TORS可能具有更好的无病生存率(DFS)和降低的游离皮瓣重建风险。TORS(TOS)与较少的肿瘤阳性切除边缘(R1)相关,较低的复发次数,术中气管切开术较少,与开放手术相比,住院时间短,术后鼻管喂养时间短。原则上,根据目前从注册研究中获得的最佳证据,I-II期口咽癌可以通过初次手术或放化疗进行治疗,生存机会相当。有了III期和IVa期的可比证据,p16neg.口咽癌,大多数作者主张将主要手术后辅助放疗或放化疗作为首选治疗方法.对于p16pos。患者的注册研究结果不一致,尽管对450例HPV阳性III期患者进行的最大注册研究显示,初次手术+辅助放化疗具有显著优势。由于所有注册研究都没有根据吸烟状况进行调整,在其他因素中,当前的数据情况应谨慎评估。
    In general, a trend towards transoral resection (as opposed to classic open approaches) + neck dissection + adjuvant radio- (chemo-) therapy has been observed for oropharyngeal carcinoma over the last 20 years. Techniques of transoral surgery (TOS), including transoral laser microsurgery (TLM) and transoral robotic surgery (TORS) have been propagated in retrospective comparisons with conventional surgery or primary radiochemotherapy as gentle, minimally invasive procedures with good late functional results. Meta-analyses of mostly uncontrolled retrospective analyses suggest that TORS may have better disease-free survival (DFS) and a reduced risk of free flap reconstruction compared with open surgery. TORS (TOS) was associated with fewer tumor-positive resection margins (R1), a lower number of recurrences, fewer intraoperative tracheostomies, a shorter inpatient stay and a shorter duration of postoperative nasal tube feeding compared to open surgery. In principle, based on the best evidence currently available from registry studies, stage I-II oropharyngeal carcinomas can be treated either with primary surgery or radiochemotherapy with a comparable chance of survival. With comparable evidence for stage III and IVa, p16neg. oropharyngeal carcinomas, the majority of authors advocate primary surgery followed by adjuvant radiotherapy or radiochemotherapy as the treatment of first choice. For p16pos. patients the results of registry studies are inconsistent, although the largest registry study on 450 HPV-positive stage III patients shows a significant superiority of primary surgery + adjuvant radiochemotherapy. Since all registry studies did not adjust for smoking status, among other factors, the current data situation should be evaluated with the necessary caution.
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  • 文章类型: Journal Article
    背景:随着人口老龄化,越来越多的老年人前来做手术。与年龄相关的生理储备和功能能力下降会导致手术后的虚弱和不良结局。因此,优化老年患者的围手术期护理势在必行。增强术后恢复(ERAS)途径和微创手术(MIS)可能会影响手术结果,但目前对老年患者的使用和影响尚不清楚.这项研究的目的是为接受大型腹部手术的老年人的围手术期护理提供循证建议。
    方法:专家共识确定了与围手术期护理相关的关键术语和指标的工作定义。使用PubMed进行了系统的文献综述和荟萃分析,Embase,科克伦图书馆,以及Clinicaltrials.gov数据库,提供24个预先定义的康复主题领域的关键问题,MIS,和ERAS在腹部大手术中(结直肠,上消化道(UGI),疝,和肝胰胆管(HPB))以根据GRADE方法生成循证建议。
    结果:老年人被定义为65岁及以上。最初从搜索参数中检索了超过20,000篇文章。在172项研究的三个主题领域进行了证据综合,对MIS和ERAS主题进行荟萃分析。建议老年患者使用MIS和ERAS,尤其是在接受结直肠手术时。专家意见建议进行康复治疗,停止吸烟和饮酒,纠正所有结直肠贫血,UGI,疝,和老年人的HPB程序。所有建议都是有条件的,证据的确定性低至非常低,结直肠手术中的ERAS项目除外。
    结论:MIS和ERAS适用于接受腹部大手术的老年人,有证据支持在结直肠手术中使用。尽管专家意见支持康复,没有足够的证据支持使用。这项工作已经确定了进一步研究的证据空白,以优化接受大型腹部手术的老年人。
    BACKGROUND: As the population ages, more older adults are presenting for surgery. Age-related declines in physiological reserve and functional capacity can result in frailty and poor outcomes after surgery. Hence, optimizing perioperative care in older patients is imperative. Enhanced Recovery After Surgery (ERAS) pathways and Minimally Invasive Surgery (MIS) may influence surgical outcomes, but current use and impact on older adults patients is unknown. The aim of this study was to provide evidence-based recommendations on perioperative care of older adults undergoing major abdominal surgery.
    METHODS: Expert consensus determined working definitions for key terms and metrics related to perioperative care. A systematic literature review and meta-analysis was performed using the PubMed, Embase, Cochrane Library, and Clinicaltrials.gov databases for 24 pre-defined key questions in the topic areas of prehabilitation, MIS, and ERAS in major abdominal surgery (colorectal, upper gastrointestinal (UGI), Hernia, and hepatopancreatic biliary (HPB)) to generate evidence-based recommendations following the GRADE methodology.
    RESULTS: Older adults were defined as 65 years and older. Over 20,000 articles were initially retrieved from search parameters. Evidence synthesis was performed across the three topic areas from 172 studies, with meta-analyses conducted for MIS and ERAS topics. The use of MIS and ERAS was recommended for older adult patients particularly when undergoing colorectal surgery. Expert opinion recommended prehabilitation, cessation of smoking and alcohol, and correction of anemia in all colorectal, UGI, Hernia, and HPB procedures in older adults. All recommendations were conditional, with low to very low certainty of evidence, with the exception of ERAS program in colorectal surgery.
    CONCLUSIONS: MIS and ERAS are recommended in older adults undergoing major abdominal surgery, with evidence supporting use in colorectal surgery. Though expert opinion supported prehabilitation, there is insufficient evidence supporting use. This work has identified evidence gaps for further studies to optimize older adults undergoing major abdominal surgery.
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  • 文章类型: Journal Article
    背景:尽管与改善患者预后有明确的关联,国家综合癌症网络(NCCN)指南的依从性仍然次优。我们试图评估患者(PC)的影响,操作(OC),和医院特征(HCs),以及不符合NCCN结肠癌指南的健康社会决定因素(SDoH)。
    方法:从国家癌症数据库中确定了2004-2017年接受I-III期结肠癌治疗的患者。进行了多层次多变量回归分析,以确定与接受NCCN依从性护理相关的因素,以及量化由PC解释的方差比例,OC,HC,和sdoh。
    结果:在1,319家医院接受治疗的468,097名结肠癌患者中,四分之一的患者没有接受符合NCCN的治疗(n=122,170,26.1%).关于回归分析,年龄较大(0.96,95%CI0.96-0.96),女性(0.97,95%CI0.96-0.99),黑人种族(0.96,95%CI0.94-0.98),更高的Charlson-Deyo评分(0.84,95%CI0.82-0.86),肿瘤分期≥II期(0.42,95%CI0.40-0.44),肿瘤分级≥3级(0.33,95%CI0.32-0.34)与接受符合NCCN标准的治疗的几率较低相关(所有p值<0.05).医院容量较高(1.02,95%CI1.02-1.03),微创或机器人手术入路(1.26,95%CI1.23-1.29),充分(≥12)淋巴结评估(3.46,95%CI3.38-3.53),私人保险状况(1.33,95%CI1.26-1.40),医疗保险状况(1.42,95%CI1.35-1.49),和较高的教育状态(1.06,95%CI1.02-1.09)与接受符合NCCN的护理的较高几率相关(所有p值<0.05).总的来说,PC贡献了36.5%,HCs贡献了1.3%,OC对指南依从性护理的变化贡献了12.9%;SDoH仅对接受NCCN依从性护理的变化贡献了3.6%。
    结论:结肠癌患者NCCN依从性治疗的差异主要归因于患者和外科医生水平的因素,而SDoH与较小比例的变异相关。
    BACKGROUND: Despite an established association with improved patient outcomes, compliance with National Comprehensive Cancer Network (NCCN) guidelines remains suboptimal. We sought to assess the effect of patient characteristics (PCs), operative characteristics (OCs), hospital characteristics (HCs), and social determinants of health (SDoH) on noncompliance with NCCN guidelines for colon cancer.
    METHODS: Patients treated for stage I to III colon cancer from 2004 to 2017 were identified from the National Cancer Database. Multilevel multivariate regression analysis was performed to identify factors associated with receipt of NCCN-compliant care and quantify the proportion of variance explained by PCs, OCs, HCs, and SDoH.
    RESULTS: Among 468,097 patients with colon cancer treated across 1319 hospitals, 1 in 4 patients did not receive NCCN-compliant care (122,170 [26.1%]). On regression analysis, older age (odds ratio [OR], 0.96; 95% CI, 0.96-0.96), female sex (OR, 0.97; 95% CI, 0.96-0.99), Black race (OR, 0.96; 95% CI, 0.94-0.98), higher Charlson-Deyo score (OR, 0.84; 95% CI, 0.82-0.86), tumor stage ≥II (OR, 0.42; 95% CI, 0.40-0.44), and tumor grade ≥ 3 (OR, 0.33; 95% CI, 0.32-0.34) were associated with lower odds of receiving NCCN-compliant care (all P values <.05). Higher hospital volume (OR, 1.02; 95% CI, 1.02-1.03), minimally invasive or robotic surgical approach (OR, 1.26; 95% CI, 1.23-1.29), adequate (≥12) lymph node assessment (OR, 3.46; 95% CI, 3.38-3.53), private insurance status (OR, 1.33; 95% CI, 1.26-1.40), Medicare insurance status (OR, 1.42; 95% CI, 1.35-1.49), and higher educational status (OR, 1.06; 95% CI, 1.02-1.09) were associated with higher odds of receiving NCCN-compliant care (all P values <.05). Overall, PCs contributed 36.5%, HCs contributed 1.3%, and OCs contributed 12.9% to the variation in guideline-compliant care, while SDoH contributed only 3.6% of the variation in receipt of NCCN-compliant care.
    CONCLUSIONS: The variation in NCCN-compliant care among patients with colon cancer was largely attributable to patient- and surgeon-level factors, whereas SDoH were associated with a smaller proportion of the variation.
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  • 文章类型: Journal Article
    预计远程外科手术将改善资源有限地区的医疗服务,促进新外科手术的快速传播,推进外科教育。虽然以前受到通信延迟和费用的阻碍,信息技术的最新进展和新手术机器人的出现创造了有利于社会实施的环境。在日本,2019年建立的法律框架允许在实际外科医生的监督下提供远程手术支持。日本外科学会领导了一项合作努力,涉及各种利益相关者,使用远程外科手术进行社会验证实验,导致2022年6月制定了日文版的“远程手术指南”。这些指南概述了医疗团队的要求,通信环境,机器人系统,和通信线路的安全措施,以及责任分配,成本负担,以及远程手术期间不良事件的处理。此外,他们解决了远程服务和完整的远程手术。预计会根据需要修订准则,基于远程手术的利用,手术机器人的进步,和信息技术的改进。
    Telesurgery is expected to improve medical access in areas with limited resources, facilitate the rapid dissemination of new surgical procedures, and advance surgical education. While previously hindered by communication delays and costs, recent advancements in information technology and the emergence of new surgical robots have created an environment conducive to societal implementation. In Japan, the legal framework established in 2019 allows for remote surgical support under the supervision of an actual surgeon. The Japan Surgical Society led a collaborative effort, involving various stakeholders, to conduct social verification experiments using telesurgery, resulting in the development of a Japanese version of the \"Telesurgery Guidelines\" in June 2022. These guidelines outline requirements for medical teams, communication environments, robotic systems, and security measures for communication lines, as well as responsibility allocation, cost burden, and the handling of adverse events during telesurgery. In addition, they address telementoring and full telesurgery. The guidelines are expected to be revised as needed, based on the utilization of telesurgery, advancements in surgical robots, and improvements in information technology.
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  • 文章类型: Journal Article
    背景:整个欧洲机器人手术系统的快速采用导致了胃肠(GI)外科医生的培训和认证方面的关键差距。目前,没有现有的标准化课程来指导机器人培训,GI学员的评估和认证。该手稿描述了通过五阶段过程就GI机器人手术综合培训计划的基本组成部分达成泛欧共识的协议。
    方法:在第一阶段,指导委员会,由国际专家组成,受训人员和教育家,已经建立,以领导和协调共识发展进程。在第二阶段,将对现有的多专业机器人培训课程进行系统审查,以告知关键职位陈述的制定。在第三阶段,将在整个欧洲进行全面调查,以了解机器人培训的现状,并确定潜在的挑战和改进的机会。在第四阶段,一个国际胃肠外科医生小组,学员,机器人剧院工作人员将参与三轮德尔福流程,在培训课程的关键方面寻求≥70%的一致意见。在整个过程中,行业和患者代表将作为外部顾问参与。在第5阶段,针对GI学员的机器人培训课程将在专门的共识会议中完成。最终产生解释和阐述(E&E)文件。
    背景:研究协议已在开放科学框架(https://osf.io/br87d/)上注册。
    BACKGROUND: The rapid adoption of robotic surgical systems across Europe has led to a critical gap in training and credentialing for gastrointestinal (GI) surgeons. Currently, there is no existing standardised curriculum to guide robotic training, assessment and certification for GI trainees. This manuscript describes the protocol to achieve a pan-European consensus on the essential components of a comprehensive training programme for GI robotic surgery through a five-stage process.
    METHODS: In Stage 1, a Steering Committee, consisting of international experts, trainees and educationalists, has been established to lead and coordinate the consensus development process. In Stage 2, a systematic review of existing multi-specialty robotic training curricula will be performed to inform the formulation of key position statements. In Stage 3, a comprehensive survey will be disseminated across Europe to capture the current state of robotic training and identify potential challenges and opportunities for improvement. In Stage 4, an international panel of GI surgeons, trainees, and robotic theatre staff will participate in a three-round Delphi process, seeking ≥ 70% agreement on crucial aspects of the training curriculum. Industry and patient representatives will be involved as external advisors throughout this process. In Stage 5, the robotic training curriculum for GI trainees will be finalised in a dedicated consensus meeting, culminating in the production of an Explanation and Elaboration (E&E) document.
    BACKGROUND: The study protocol has been registered on the Open Science Framework (https://osf.io/br87d/).
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  • 文章类型: Journal Article
    背景:机器人胰十二指肠切除术(RPD)是一种新引入的手术,仍在发展,缺乏标准化。客观评估对于研究RPD的可行性至关重要。目前的研究旨在评估我们最初的10例基于IDEAL的RPD(Idea,发展,探索,评估,和长期研究)指南。
    方法:这是一项遵循IDEAL框架的前瞻性2a期研究。由两名具有开放手术专业知识的外科医生在一个中心进行的连续10例RPD被分配到研究中。客观评价,根据程序的成就,每例分为四个等级。在前一种情况下观察到的错误用于在下一种情况下通知程序。回顾了10例患者的手术效果。
    结果:中位总手术时间为634分钟(四分位距[IQR],594-668),中位切除时间为363分钟(IQR,323-428)和123分钟的重建时间(IQR,107-131).整个程序的成就被评为A级,\"成功\",两个病人。在两个病人中,由于广泛的气腹,采用小型剖腹手术进行了重建,可能是由于插入了一个来自氧磷的肝脏牵开器。2例患者术后发生主要并发症。一个病人,其中空肠肢体通过Treitz韧带抬高,患有肠梗阻,需要再次剖腹手术。
    结论:由在开放手术中有经验的外科医生进行RPD是可行的。需要具体考虑以安全地引入RPD。
    BACKGROUND: Robotic pancreatoduodenectomy (RPD) is a newly introduced procedure, which is still evolving and lacks standardization. An objective assessment is essential to investigate the feasibility of RPD. The current study aimed to assess our initial ten cases of RPD based on IDEAL (Idea, Development, Exploration, Assessment, and Long-term study) guidelines.
    METHODS: This was a prospective phase 2a study following the IDEAL framework. Ten consecutive cases of RPD performed by two surgeons with expertise in open procedures at a single center were assigned to the study. With objective evaluation, each case was classified into four grades according to the achievements of the procedures. Errors observed in the previous case were used to inform the procedure in the next case. The surgical outcomes of the ten cases were reviewed.
    RESULTS: The median total operation time was 634 min (interquartile range [IQR], 594-668) with a median resection time of 363 min (IQR, 323-428) and reconstruction time of 123 min (IQR, 107-131). The achievement of the whole procedure was graded as A, \"successful\", in two patients. In two patients, reconstruction was performed with a mini-laparotomy due to extensive pneumoperitoneum, probably caused by insertion of a liver retractor from the xyphoid. Major postoperative complications occurred in two patients. One patient, in whom the jejunal limb was elevated through the Treitz ligament, had a bowel obstruction and needed to undergo re-laparotomy.
    CONCLUSIONS: RPD is feasible when performed by surgeons experienced in open procedures. Specific considerations are needed to safely introduce RPD.
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  • 文章类型: Journal Article
    目的:没有研究依靠标准化的方法来收集机器人辅助根治性膀胱切除术(RARC)后的并发症。我们研究的目的是评估接受RARC的患者的围手术期和术后结果,这些患者遵循欧洲泌尿外科协会(EAU)报告手术结果并进行长期术后随访的建议。
    方法:246例患者在一个三级转诊中心接受RARC治疗,术后随访≥1年。通过医生的访谈前瞻性收集术后结果。使用Clavien-Dindo分类(CD)对并发症进行评分,按类型和严重程度分组(严重:CD评分≥3)。我们描述了围手术期和术后结果以及并发症的时间分布。
    结果:总体而言,16例(6.5%)和225例(91%)患者经历了术中和术后并发症,分别。此外,139(57%)经历了严重的并发症。最常见的任何级别和严重的并发症是感染性(72%)和泌尿生殖系统(35%),分别。总的来说,52%的并发症(358/682)发生在手术后10天内,51%的严重并发症(106/207)发生在35天内.然而,13%的并发症(90/682)和28%的严重并发症(59/207)发生在术后3个月。最早的并发症是不明原因的发热和麻痹性肠梗阻(中位并发症时间[mTTC]:4天),最新的并发症是尿路感染(mTTC:40天)和肾积水/输尿管梗阻(mTTC:70天).
    结论:当实施标准化收集方法和长期随访时,RARC术后并发症的发生率>90%。这些结果应用于确定潜在的改善区域和术前患者咨询。
    OBJECTIVE: No studies relied on a standardized methodology to collect postoperative complications after robot-assisted radical cystectomy (RARC). The aim of our study was to evaluate peri- and post-operative outcomes of patients undergoing RARC adhering to the European Association of Urology (EAU) recommendations for reporting surgical outcomes and using a long postoperative follow-up.
    METHODS: 246 patients who underwent RARC with intracorporal urinary diversion at a single tertiary referral center with a postoperative follow-up ≥ 1 year for survivors. Postoperative outcomes were collected prospectively by interviews done by medical doctors. Complications were scored using the Clavien-Dindo classification (CD), grouped by type and severity (severe: CD score ≥ 3). We described peri- and post-operative outcomes and complication chronological distribution.
    RESULTS: Overall, 16 (6.5%) and 225 patients (91%) experienced intraoperative and postoperative complications, respectively. Moreover, 139 (57%) experienced severe complications. The most common any-grade and severe complications were infectious (72%) and genitourinary (35%), respectively. Overall, 52% of complications (358/682) occurred within 10 days from surgery, and 51% of severe complications (106/207) occurred within 35 days. However, 13% of complications (90/682) and 28% of severe complications (59/207) occurred 3 months after surgery. The earliest complications were fever of unknown origins and paralytic ileus (median time-to-complication [mTTC]: 4 days), the latest complications were urinary tract infection (mTTC: 40 days) and hydronephrosis/ureteral obstruction (mTTC: 70 days).
    CONCLUSIONS: The rate of postoperative complications after RARC is > 90% when a standardized collection method and a long follow-up is implemented. These results should be used to identify potential areas of improvement and for preoperative patient counseling.
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  • 文章类型: Journal Article
    在头颈部手术中,经口机器人手术(TORS)正在发展成为口咽良性和恶性病变的关键治疗选择。即便如此,术后疼痛是TORS后的主要早期主诉之一.建立良好的循证程序特异性疼痛治疗指南可用于各种其他外科专业。然而,没有TORS的指导方针。
    本综述描述了在休息和手术相关活动期间TORS后早期疼痛强度的可用数据。
    关于TORS术后即刻疼痛的文献来自两个文献数据库。
    关于TORS后疼痛强度的大多数数据是基于数字评定量表,例如视觉模拟量表和/或镇痛需求。只有一项随机临床试验可用,反映文献主要基于回顾性研究和一些前瞻性研究。只有一项研究分析了相关功能期间的疼痛,即吞咽。总的来说,这些研究受到非标准化方法的困扰,并且需要有关疼痛评级和方法的时间安排的透明信息.
    最佳疼痛控制的证据有限,特别是在手术相关活动期间。活动过程中的术后疼痛评分是疼痛试验中的基本要素,以增强恢复,从而呼吁在评估方法上达成共识。
    UNASSIGNED: In Head and Neck surgery Transoral Robotic Surgery (TORS) is evolving as a key treatment option for benign and malignant lesions in the oropharynx. Even so, postoperative pain is one of the primary early complaints following TORS. Well established evidence-based procedure specific pain treatment guidelines are available for a variety of other surgical specialties. However, there are no guidelines for TORS.
    UNASSIGNED: This review describes the available data of early pain intensity following TORS during rest and procedure related activity.
    UNASSIGNED: Literature concerning pain in the immediate postoperative phase following TORS were obtained from two literature databases.
    UNASSIGNED: Most data on pain intensity following TORS are based upon a numeric rating scale, e.g. the Visual Analogue Scale and/or analgesic demands. Only one randomized clinical trial is available reflecting that the literature is mainly based on retrospective and a few prospective studies. Only one study analyzed pain during relevant functionality, i.e. swallowing. Overall, the studies suffer from a non-standardized approach and there is a need for transparent information concerning the timing of pain ratings and methodology.
    UNASSIGNED: The evidence for optimal pain control is limited, particularly during surgical relevant activity. Postoperative pain rating during activity is a fundamental element in pain trials in order to enhance recovery thereby calling for future consensus on assessment methodology.
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