背景:原发性乳腺癌引起的甲状腺转移是一种罕见的现象,只有少数案例记录在国内和国际文献中。这种情况的管理方法和预后引发了争论和不确定性。
方法:这里,我们报道了一例55岁的乳腺癌患者。她先前接受了辅助化疗和内分泌治疗的广泛切除乳腺病变。9年后,患者出现颈部不适,检查提示右侧甲状腺转移和颈部淋巴结转移。影像学显示肺和骨转移。此外,患者接受内分泌治疗.经过7个月的随访,患者存活,无任何新的远处转移.源自乳腺癌的甲状腺转移通常以一种微妙的方式展开,错综复杂的性质,使早期检测具有挑战性。它们往往不显眼地出现,与广泛的全身转移交织在一起,暗示预后较差。
结论:鉴于异常的临床指标,识别肿瘤患者的异慢性甲状腺转移是一个独特的挑战,要求临床医生以更高的灵敏度驾驭随访过程。关键在于及时发现,及早干预,能显著提高患者整体生活质量的因素。
BACKGROUND: Thyroid metastasis arising from primary breast cancer is a rare phenomenon, with only a handful of cases documented in both national and international literature. The management approach and prognosis of this occurrence have sparked debates and uncertainties.
METHODS: Herein, we report the
case of a 55-year-old woman with breast cancer. She previously underwent extensive excision of the breast lesion with adjuvant chemotherapy and endocrine therapy. After 9 years, she presented with neck discomfort and examination suggested right thyroid metastasis and lymph node metastasis in the neck. Imaging showed pulmonary and bone metastases. Furthermore, the patient received endocrine therapy. After 7 months of follow- up, the patient survived without any new distant metastases. Thyroid metastases originating from breast cancer often unfold with a subtle, intricate nature, making early detection challenging. They tend to emerge inconspicuously, intertwining with widespread systemic metastases, hinting at a less favorable prognosis.
CONCLUSIONS: Given the unusual clinical indicators, identifying heterochronic thyroid metastases in patients with tumors poses a distinct challenge, requiring clinicians to navigate the follow-up process with heightened sensitivity. The key lies in timely detection and early intervention, factors that can significantly enhance the overall quality of life for patients.