Abstract：
BACKGROUND: Desmoplastic fibroma (DF) is an extremely rare locally aggressive bone tumor with an incidence of 0.11% of all primary bone tumors. The typical clinical presentation is pain and swelling above the affected area. The most common sites of involvement are the mandible and the metaphysis of long bones. Histologically and biologically, desmoplastic fibroma mimics extra-abdominal desmoid tumor of soft tissue.
UNASSIGNED: A case of a 27-year old man with DF in the ilium, including the clinical, radiological and histological findings over a 4-year period is presented here. CT scans performed in 3-year intervals prior to surgical intervention were compared with respect to tumor extension and cortical breakthrough. The patient was treated with curettage and grafting based on anatomical considerations. Follow-up CT scans over 18-months are also documented here. Additionally, a review and analysis of 271 cases including the presented case with particular emphasis on imaging patterns in MRI and CT as well as treatment modalities and outcomes are presented.
CONCLUSIONS: In patients with desmoplastic fibroma, CT is the preferred imaging technique for both the diagnosis of intraosseus tumor extension and assessment of cortical involvement, whereas MRI is favored for the assessment of extraosseus tumor growth and preoperative planning. While tumor resection remains the preferred treatment for DF, curettage and grafting prove to be an acceptable alternative treatment modality with close follow-up when resection is not possible. Curettage and grafting have been shown to provide good clinical results and are associated with long recurrence free intervals.
UNASSIGNED: A case of a 27-year old man with DF in the ilium, including the clinical, radiological and histological findings over a 4-year period is presented here. CT scans performed in 3-year intervals prior to surgical intervention were compared with respect to tumor extension and cortical breakthrough. The patient was treated with curettage and grafting based on anatomical considerations. Follow-up CT scans over 18-months are also documented here. Additionally, a review and analysis of 271 cases including the presented case with particular emphasis on imaging patterns in MRI and CT as well as treatment modalities and outcomes are presented.
CONCLUSIONS: In patients with desmoplastic fibroma, CT is the preferred imaging technique for both the diagnosis of intraosseus tumor extension and assessment of cortical involvement, whereas MRI is favored for the assessment of extraosseus tumor growth and preoperative planning. While tumor resection remains the preferred treatment for DF, curettage and grafting prove to be an acceptable alternative treatment modality with close follow-up when resection is not possible. Curettage and grafting have been shown to provide good clinical results and are associated with long recurrence free intervals.
摘要：
背景：促纤维化瘤（DF）是一种极为罕见的局部侵袭性骨肿瘤，占所有原发性骨肿瘤的0.11％。典型的临床表现是受影响区域上方的疼痛和肿胀。最常见的受累部位是下颌骨和长骨干meta端。组织学和生物学，促纤维增生性纤维瘤模仿软组织的腹外硬纤维瘤。
■一例27岁的男子，髂骨有DF，包括临床，放射学和组织学发现超过4年的时间在这里介绍。比较了手术干预前3年间隔进行的CT扫描与肿瘤扩展和皮质突破的关系。根据解剖学考虑，对患者进行刮治和移植治疗。18个月的后续CT扫描也记录在这里。此外,我们对271例病例进行了回顾和分析,包括本病例,重点介绍了MRI和CT的成像模式以及治疗方式和结果.
结论：在纤维增生性纤维瘤患者中，CT是诊断骨内肿瘤扩展和评估皮质受累的首选成像技术。而MRI有利于评估骨外肿瘤的生长和术前计划。虽然肿瘤切除仍然是DF的首选治疗方法，刮治和移植被证明是一种可接受的替代治疗方式，当无法切除时，应密切随访。刮治和移植已显示出良好的临床效果，并且与长时间的无复发间隔有关。
■一例27岁的男子，髂骨有DF，包括临床，放射学和组织学发现超过4年的时间在这里介绍。比较了手术干预前3年间隔进行的CT扫描与肿瘤扩展和皮质突破的关系。根据解剖学考虑，对患者进行刮治和移植治疗。18个月的后续CT扫描也记录在这里。此外,我们对271例病例进行了回顾和分析,包括本病例,重点介绍了MRI和CT的成像模式以及治疗方式和结果.
结论：在纤维增生性纤维瘤患者中，CT是诊断骨内肿瘤扩展和评估皮质受累的首选成像技术。而MRI有利于评估骨外肿瘤的生长和术前计划。虽然肿瘤切除仍然是DF的首选治疗方法，刮治和移植被证明是一种可接受的替代治疗方式，当无法切除时，应密切随访。刮治和移植已显示出良好的临床效果，并且与长时间的无复发间隔有关。
