Lichen sclerosus (LS) is a chronic inflammatory dermatosis typical of the genital region, with rare involvement of extragenital areas and particularly the face. LS therapeutic management is challenging, and common therapies including topical and systemic corticosteroids, topical calcineurin inhibitors, surgery are often ineffective. Herein, we present a case of LS occurred in a 36-year-old girl with facial involvement resistant to therapy with systemic corticosteroids and topical tacrolimus. Considering the involvement of a sensitive area, the young age of the patient, and the consistent clinical experience in using photodynamic therapy for the treatment of facial skin disease, we started a treatment with topical 5-aminolevulinic acid (ALA)-photodynamic therapy (PDT) with a dosage of 37 J/cm2 once a month. We compared our case with eight other facial LS patients from the literature and treated differently.

Surgical scar formation afflicts patients and current treatments are limited by inconsistent efficacy, long-term and painful treatment processes. In this report, a patient received 5-aminolevulinic acid-mediated photodynamic therapy (5-ALA PDT) on the first postoperative day, once a week for 5 sessions. At two-year follow-up, the intervention of 5-ALA PDT at early stage decreased the vascular density and improved extracellular matrix (ECM) deposition. The early intervention of surgical scar by 5-ALA PDT overcomes the penetration limits of photosensitizer and red light, making it a potential strategy for surgical scar prevention.

Shoulder capsulitis is a painful condition in which movement of the shoulder becomes limited. Objective: The aim, based on study of a single case, was to evaluate subjective and objective short-term effects of radiation of the shoulder joint using LED red light (630nm, 37.5 Jcm over 500s) in a case of chronic shoulder capsulitis. The case was a 96-year-old man with painful and restricted movement of the right shoulder joint. A record was made of parameters before the start of treatment using the Oxford Shoulder Score [1] and repeated following 12 treatment sessions in a four-week period. Results indicate improvement in a number of parameters and almost pain free essential movement without use of NSAI gel. On the basis of findings, the method warrants a pilot study to test reproducibility and to establish optimal number of treatments. Treatment was to two areas.

PBMT using 630 + 660 nm wavelengths transcutaneously at 7 cm above chest area irradiating lungs and heart regions of patients with acute, infectious respiratory syndrome alleviated their respiratory symptoms, mitigated pulmonary inflammation and hypoxia. PBMT could prevent more severe respiratory distress requiring emergency care and reduce the strain on healthcare. This case report\'s clinical experience can be the basis of future research evaluating oxygen saturation levels pre- and post-PBMT.