radical excision

根治性切除术
  • 文章类型: Case Reports
    背景:淋巴瘤(LH)是最常见的淋巴管瘤类型,但它很少发生在前臂。它可能显示局部侵入行为,但是是良性的。
    方法:一位42岁的妇女出现在我们医院,她的右前臂有一个长条状肿块,3年前就发现了。超声检查显示右前臂皮下有一条下背声带。进一步的磁共振成像(MRI)显示LH特有的不规则带状扩张淋巴管,T1信号强度低,T2信号强度高。根治性手术切除后,用单克隆抗体D2-40标记的囊性LH内皮细胞的苏木精-伊红(H&E)和免疫组织化学(IHC)染色显示扩张的淋巴管瘤,没有恶性肿瘤的迹象。经过7个月的随访,未见肿瘤复发,疗效满意。
    先前创伤史的组合,症状和体征,影像学评估是必要的,以提供LH的线索,但最终的诊断可能是通过切除标本的病理评估。虽然有许多治疗方式,都有不同的结果。导致肿瘤残留的完全切除是LH复发的首要原因。因此,我们认为针对LH的首选方法仍然是完全手术切除。
    结论:LH是良性的,通常无症状的病变,具有轻度的生物学行为。由于偶尔会有令人困惑的演示,类似的囊性病变仍应谨慎考虑。尽管MRI为其诊断提供了优越的优势,确诊仍需进行组织学检查.根治性病灶切除术是治疗LH的一种非常安全有效的选择。
    BACKGROUND: Lymphoma hygroma (LH) that is the most common type of lymphangioma, but it rarely occurs in the forearm. It may show localized invasive behavior, but is benign.
    METHODS: A 42-year-old woman presented to our hospital with a growing strip-like mass in the right forearm that had been detected 3 years earlier. Ultrasound examination showed a subcutaneous strip of low back vocal cords on the right forearm. Further magnetic resonance imaging (MRI) showed irregular strip-like dilated lymphatic vessels characteristic of LH with low T1 signal intensity and high T2 signal intensity. After radical surgical resection, hematoxylin-eosin (H & E) and immunohistochemical (IHC) staining of cystic LH endothelial cells labeled with monoclonal antibody D2-40 showed a dilated lymphangioma with no evidence of malignancy. After 7 months of follow-up, no tumor recurrence was seen and the effect was satisfactory.
    UNASSIGNED: A combination of previous trauma history, signs and symptoms, and imaging evaluation are necessary to provide clues to LH, but the final diagnosis is likely to be made by pathologic evaluation of the resected specimen. Although there are many treatment modalities, all also have different outcomes. The absence of complete resection resulting in a tumor remnant is the foremost cause of LH recurrence, so we believe that the preferred approach against LH remains complete surgical resection.
    CONCLUSIONS: LH is benign and generally asymptomatic lesions with mild bio-behavior. As there are occasional confusing presentations, similar cystic lesions should still be considered with caution for the disease. Although MRI provides superior advantages for its diagnosis, the confirmation of diagnosis still requires histological examination. Radical lesion resection is a very safe and effective option for the treatment of LH.
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  • 文章类型: Case Reports
    背景:颅内间叶性软骨肉瘤(MSC)是一种极其罕见的肿瘤,仅占所有中枢神经系统肿瘤的0.015%。这些肿瘤通常起源于颅底综合征,通常在年轻人的第二个和第三个十年中观察到。尽管在辅助放疗方面没有达成共识,根治性切除对于MSC的预后仍然至关重要。
    方法:我们在此介绍一名年轻男性患者的颅内MSC,恶性肿瘤,尚未就其治疗达成共识。患者接受了根治性切除术,然后进行辅助放疗。组织学分析显示,分化不良的肿瘤含有坏死区域。值得注意的是,6年后未观察到复发迹象。
    结论:长期随访期间无复发提示根治性切除和辅助放疗的重要性。
    BACKGROUND: Intracranial mesenchymal chondrosarcoma (MSC) is an extremely rare tumour that constitutes only 0.015% of all central nervous system tumours. These tumours usually originate from skull base synchondrosis and are often observed in young adults during their second and third decades of life. Despite the absence of a consensus regarding adjuvant radiotherapy, radical excision remains crucial for the prognosis of MSC.
    METHODS: We herein present the case of a young male patient with intracranial MSC, a malignant tumour, for which no consensus regarding its treatment has yet been established. The patient underwent radical excision followed by adjuvant radiotherapy. Histological analysis revealed a poorly differentiated tumour containing necrotic areas. Notably, no signs of recurrence had been observed after 6 years.
    CONCLUSIONS: The absence of recurrence over a long follow-up duration suggests the importance of radical excision and adjuvant radiotherapy.
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    文章类型: Case Reports
    隆突性皮肤纤维肉瘤(DFSP)是非常罕见的皮肤真皮层肿瘤,每年仅1例。DFSP很少导致转移(少于5%有转移),但DFSP可以在本地复发。我们发表了一例罕见的复发性隆突性皮肤纤维肉瘤及其根治性切除和间隔植皮治疗。
    Dermatofibrosarcoma protuberans (DFSP) is very rare tumor of dermis layer of skin with the incidence of only 1 case per million per year. DFSP rarely leads to a metastasis (Less than 5% have metastasis), but DFSP can recur locally. We publish a rare case of a recurrent dermatofibrosarcoma protuberans and its management with radical excision and interval skin grafting.
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  • 文章类型: Case Reports
    We report a rare case of 50-year-old Moroccan woman with local recurrence of a subcutaneous hydatid cyst in proximity to the medial surface of the tibia and another cyst at the tibialis posterior muscle in the absence of liver, lung und spleen involvement. The first surgery was done in another hospital three years ago; no adjuvant treatment was performed after surgery. Recurrence was diagnosed according to the MRI appearance, serological and pathological findings. The patient underwent complete excision of the subcutaneous cyst with two centimeters of the medial gastrocnemius muscle; the tibialis posterior muscle cyst was intraoperatively drained and irrigated with scolicidal agent as it was next to the posterior tibial pedicle. A periopertive anthelmintic chemotherapy was administered. Two years after the patient showed no recurrence. This case report and literature review describe an approach to the diagnosis and management of this pathological entity.
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    文章类型: Case Reports
    In medical practice, plastic surgeons confront with patients with sarcomas of the extremities that require a radical surgical approach. Knowing when to attempt limb-sparing surgery and when to give in to limb amputation is one of the most difficult decisions a surgeon can take. The correct approach and management of such cases ensure surgical success and the patient survival. In this paper, the case of a 56-year-old man, admitted in our clinic with a crush injury of the right calf and subsequent haematoma is presented. During haematoma drainage, the surgeon noticed abnormal tissue and performed an incisional biopsy. The patient was diagnosed with myxoid liposarcoma of the external compartment of the right calf. Limb amputation was proposed, but the patient refused. After the clinical examination, blood tests and diagnostic imaging, which allowed the correct evaluation of the case-tumor sizes and neighboring tissue reports, and preoperatory radiotherapy, limb sparing surgery, respectively primary tumor excision was decided to be performed. Negative margins could not be obtained by 3 successive resections or by adjuvant chemotherapy. The presented case supports the idea that limb-sparing surgery is only applicable to carefully selected patients with soft tissue sarcoma. In some cases, radical excision involving even mutilating amputations may provide a better oncologic and functional result.
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  • 文章类型: Case Reports
    Ameloblastomas are rare, slowly growing and locally invasive tumours with high recurrence rate, if not treated they can grow to enormous size; we report five such cases in our article and discuss their surgical management. We report five cases of giant ameloblastoma presented in our institute between 2007 and 2010, we treated them surgically with wide margin of resection. It is widely reported that recurrence of ameloblastoma in many cases reflects the inadequacy or failure of the primary surgical procedure. We treated all our cases with radical excision with free flap reconstruction with no recurrence in any of our patients in 2 years follow-up. Radical excision of these benign but locally invasive lesions, which grows to giant size with reconstruction using micro vascular free flaps forms the best modality of treatment.
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  • 文章类型: Journal Article
    Recurrence after surgical treatment of hydatid cyst of the spine is extremely common. Preexisting fibrosis, fragility of the cyst wall, confluent cysts and proximity to vital structures makes radical excision difficult and repeated recurrences are inevitable. This case report describes a recurrent hydatid cyst presenting as three separate cysts in the dorsal spine in a middle-aged male. The extradural cyst caused paraplegia. The extraspinal cyst presented as an extrapleural mass in relation with the eighth, ninth and the tenth ribs near the costo-vertebral junction. The three cysts were resected en masse. Complete neurological recovery occurred with no recurrence at four years follow-up. Resection of the hydatid cyst en masse offers the best chance of cure and must be attempted in all cases. A prolonged chemotherapy should be administered in all cases.
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