■网虫病是人类由寄生虱子引起的最常见的恼人感染之一。拟除虫菊酯是用于治疗这种感染的主要杀虫剂之一。但是最近,由于虱子对这类杀虫剂的抗性,其杀虫效果受到影响。本研究是通过荟萃分析进行的,以调查全世界对这些杀虫剂的拟除虫菊酯抗性的患病率。
■这项研究是对全球人类头虱对拟除虫菊酯杀虫剂的治疗抗性的流行进行的荟萃分析。基于此,到2022年6月底在PubMed/MEDLINE上无时间限制发表的所有文章,WebofScience(ISI)Scopus,和GoogleScholar数据库进行提取,并在荟萃分析中使用随机效应荟萃分析模型统计方法,科克伦,通过STATA软件分析指数I2和漏斗图。
■20项研究被纳入荟萃分析过程。据此,拟除虫菊酯抗性杀虫剂在人类头虱中的患病率估计为59%(CI95%:50%-68%)。在拟除虫菊酯类杀虫剂中,除虫菊酯对氯菊酯杀虫剂的抗性最高,为65%。关于每年抵抗的患病率,2004年之前的患病率估计为33%,但在2015年之后,这一比率达到了82%。此外,使用基因诊断方法估计大多数拟除虫菊酯耐药为68%,使用临床诊断方法估计为43%.
■超过一半的人类头虱拟除虫菊酯抗性杀虫剂。基于此,建议在使用这种治疗方法治疗人类头虱感染之前,它应该调查该地区对拟除虫菊酯的耐药性,如果大多数抵抗力量很高,应使用替代或联合治疗方法。
UNASSIGNED: Pediculosis is one of the most common annoying infections caused by parasitic lice in humans. Pyrethroids are one of the main insecticides used to treat this infection. But recently, due to the Resistance of lice to this group of insecticides, its insecticidal effects have been affected. The present
study was conducted through a meta-analysis to investigate the prevalence of
pyrethroid resistance against these insecticides worldwide.
UNASSIGNED: This
study was conducted as a meta-analysis of the prevalence of treatment resistance in human head lice against
pyrethroid insecticides worldwide. Based on this, all articles published without a time limit until the end of June 2022 in PubMed/MEDLINE, Web of Science (ISI), Scopus, and Google Scholar databases were extracted and using random-effects meta-analysis model statistical methods in the meta-analysis, Cochrane, Index I2, and funnel plot were analyzed by STATA software.
UNASSIGNED: Twenty studies were included in the meta-analysis process. According to this, the prevalence of pyrethroid resistance insecticides in human head lice was estimated at 59% (CI95%: 50%-68%). Among
pyrethroid insecticides, the highest prevalence of
pyrethroid resistance against permethrin insecticide was 65%. Regarding the prevalence of Resistance by year, the prevalence before 2004 was estimated at 33%, but after 2015, this rate reached 82%. Also, the majority of pyrethroid resistance was estimated at 68% using genetic diagnosis methods and 43% using clinical diagnosis methods.
UNASSIGNED: More than half of human head lice
pyrethroid resistance insecticides. Based on this, it is recommended that before using this treatment method to treat human head lice Infestation, it should investigate the prevalence of pyrethroid resistance in that area, and if the majority of Resistance is high, alternative or combined treatment methods should be used.