pulmonary lobectomy

肺叶切除术
  • 文章类型: Journal Article
    反复喘息在婴儿中非常常见。当这些症状出现在没有自由间隔的早期,应该调查肺畸形。先天性大叶气肿是一种罕见的下呼吸道异常。这里,我们报告了2015年至2023年间6例先天性大叶气肿病例。临床和放射学数据是根据先前在我们的小儿肺炎变态反应科建立的手术表收集的。他们都有反复喘息和呼吸困难。胸部X线和胸部CT与先天性大叶气肿的诊断一致。所有患者均行肺叶切除术,无并发症。
    Recurrent wheezing is very common in infants. When these symptoms appear early without a free interval, a pulmonary malformation should be investigated. Congenital lobar emphysema is a rare abnormality of the lower respiratory tract. Here, we report a case series of six cases of congenital lobar emphysema between 2015 and 2023. Clinical and radiological data were collected according to an operating sheet previously established in our pediatric pneumo-allergology unit. They all had recurrent wheezing and dyspnea. Chest radiography and chest CT were consistent with the diagnosis of congenital lobar emphysema. All patients had lobectomy without complications.
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  • 文章类型: Case Reports
    我们报告2例肺叶切除术后急性近端前循环闭塞。
    病例1是一名64岁男性,在左下叶切除术后一天出现右大脑中动脉(MCA)闭塞。病例2是一名68岁的男性,表现为右颈内动脉(ICA)闭塞。在这两种情况下,进行了机械血栓切除术以完全再通,症状得到改善。
    肺叶切除术后急性期的机械血栓切除术可改善急性近端前循环闭塞患者的预后。与从事胸外科的医务人员共享有关缺血并发症的信息很重要。
    UNASSIGNED: We report two cases of acute proximal anterior circulation occlusion after pulmonary lobectomy.
    UNASSIGNED: Case 1 was a 64-year-old male who presented with occlusion of the right middle cerebral artery (MCA) one day after left lower lobectomy. Case 2 was a 68-year-old male who presented with occlusion of the right internal carotid artery (ICA). In both cases, mechanical thrombectomy was performed for complete recanalization and symptoms were improved.
    UNASSIGNED: Prompt mechanical thrombectomy in the acute phase after pulmonary lobectomy improved the prognosis of patients with acute proximal anterior circulation occlusion. It is important to share information about ischemic complications with medical staff engaged in thoracic surgery.
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  • 文章类型: Journal Article
    左肺叶切除术后由肺静脉残端血栓引起的脑栓塞性中风是严重的并发症。我们回顾性分析了2014年1月至2022年3月在左肺叶切除术后行机械血栓切除术治疗大血管闭塞的4例患者。2例发生在左上叶切除术后,其余发生在左下叶切除术后。所有患者从术后第3天到术后第9天出现脑栓塞性脑卒中,所有病例均成功再灌注。两名患者在90天有良好的结果。肺静脉残端血栓是脑栓塞的可能原因,机械血栓切除术是有效的。需要进一步研究以建立预防措施和围手术期管理策略。
    Cerebral embolic stroke caused by a thrombus in the pulmonary vein stump after left pulmonary lobectomy is a serious complication. We retrospectively analyzed four patients who underwent mechanical thrombectomy for large-vessel occlusion after left pulmonary lobectomy between January 2014 and March 2022. Two cases occurred after left upper lobectomy and the others occurred after left lower lobectomy. All patients presented with cerebral embolic stroke from the day after surgery to the 9th postoperative day, and successful reperfusion was achieved in all cases. Two patients had good outcomes at 90 days. Thrombus in the pulmonary vein stump is the probable cause of cerebral embolism, and mechanical thrombectomy is effective. Further studies are required to establish preventive measures and perioperative management strategies.
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  • 文章类型: Journal Article
    目的:我们分析了肺叶切除术后不久发生大血管闭塞(LVO)的急性缺血性卒中(AIS)患者的预后。
    方法:我们回顾了接受肺叶切除术治疗原发性肺癌患者的临床记录。我们检索了LVO患者的临床特征和AIS发生率。回顾了经历AIS的患者的临床过程。
    结果:在3406例患者中,有10例(0.3%),肺叶切除术后(3天内)伴有LVO的AIS很快发展。8例患者(80%)的肺切除部位在左侧。所有患者均接受了血栓切除术并实现了完全再通(脑梗死溶栓[TICI]3)。症状发作和再通之间的平均时间为165.5分钟。9例(90%)患者在3个月随访时表现出良好的预后(改良Rankin量表[mRS]评分≤2)。
    结论:血管内治疗可有效治疗肺手术后发生的伴LVO的AIS,直接愿望是一个有前途的策略。一个大的,多中心研究有必要进一步证实这些发现.
    OBJECTIVE: We analyzed the outcomes of patients suffering acute ischemic stroke (AIS) with large vessel occlusion (LVO) soon after pulmonary lobectomy.
    METHODS: We retrospectively reviewed the clinical records of patients who underwent pulmonary lobectomy to treat primary lung cancer. We retrieved clinical characteristics and the incidence of AIS with LVO. The clinical courses of patients who experienced AIS were reviewed.
    RESULTS: In 10 (0.3%) of 3406 patients, AIS with LVO developed soon (within 3 days) after pulmonary lobectomy. The lung resection site was on the left in eight patients (80%). All patients underwent thrombectomy and achieved complete recanalization (Thrombolysis in Cerebral Infarction [TICI] 3). The average time between symptom onset and recanalization was 165.5 min. Nine (90%) patients exhibited favorable outcomes (modified Rankin scale [mRS] score ≤ 2) at the 3-month follow-up.
    CONCLUSIONS: Endovascular therapy effectively treats AIS with LVO that develops after lung surgery, and direct aspiration is a promising strategy. A large, multicenter study is warranted to further confirm these findings.
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  • 文章类型: Case Reports
    全位倒位(SIT)和肺癌的共存极为罕见;因此,文献中只有一个病例报告。内窥镜手术的最新技术进步允许在这些情况下执行视频胸腔镜肺切除术。然而,胸部结构的独特位置,支气管血管解剖学,应使用支气管镜检查和对比增强计算机断层扫描(CT)检查SIT的其他异常。我们介绍了一名50岁的SIT女性患者的电视胸腔镜左上叶切除术和纵隔淋巴结清扫的病例报告。
    The coexistence of situs inversus totalis (SIT) and lung cancer is exceedingly rare; therefore, only a single case report about this exists in the literature. Recent technological advancements in endoscopic surgery have allowed the execution of videothoracoscopic lung resection in these cases. However, the distinct placement of thoracic structures, bronchovascular anatomy, and additional anomalies in SIT should be investigated using bronchoscopy and contrast-enhanced computed tomography (CT). We present a case report of a videothoracoscopic left upper lobectomy with mediastinal lymph node dissection in a 50-year-old female patient with SIT.
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  • 文章类型: Journal Article
    肺叶切除术是肺癌切除的金标准干预措施,包括完全切除受影响的肺叶,which,再加上其余的胸部结构的重新适应,降低患者术后肺功能。目前的临床实践,基于肺活量测定和心肺运动试验,不考虑局部变化,提供剩余功能的平均口估计。计算流体动力学(CFD)已被证明是获得有关气道气流动力学的定量和局部信息的有价值的解决方案。对左上肺叶切除术患者的气道树进行了CFD调查,量化术后改变的影响。根据术前和术后CT扫描重建患者特异性支气管模型。将参数喉部模型合并到几何形状中以说明类似生理的入口条件。在Fluent中进行了数值模拟。术后配置显示整体速度的流体动力学变化(+23%),壁压(+48%),和墙剪应力(+39%)。切除部位出现局部流量扰动:在左下叶入口处发现了4.92m/s的高速峰值,随着缝合区压力的局部增加(18Pa)。气管中压力和二次流量的大小增加,对侧肺中也观察到流量动力学变化,导致肺叶通气改变。结果证实,CFD是一种针对患者的方法,可对流体动力学参数和局部通气进行定量评估,从而为当前的临床方法提供更多信息。
    Pulmonary lobectomy is the gold standard intervention for lung cancer removal and consists of the complete resection of the affected lung lobe, which, coupled with the re-adaptation of the remaining thoracic structures, decreases the postoperative pulmonary function of the patient. Current clinical practice, based on spirometry and cardiopulmonary exercise tests, does not consider local changes, providing an average at-the-mouth estimation of residual functionality. Computational Fluid Dynamics (CFD) has proved a valuable solution to obtain quantitative and local information about airways airflow dynamics. A CFD investigation was performed on the airway tree of a left-upper pulmonary lobectomy patient, to quantify the effects of the postoperative alterations. The patient-specific bronchial models were reconstructed from pre- and postoperative CT scans. A parametric laryngeal model was merged to the geometries to account for physiological-like inlet conditions. Numerical simulations were performed in Fluent. The postoperative configuration revealed fluid dynamic variations in terms of global velocity (+23%), wall pressure (+48%), and wall shear stress (+39%). Local flow disturbances emerged at the resection site: a high-velocity peak of 4.92 m/s was found at the left-lower lobe entrance, with a local increase of pressure at the suture zone (18 Pa). The magnitude of pressure and secondary flows increased in the trachea and flow dynamics variations were observed also in the contralateral lung, causing altered lobar ventilation. The results confirmed that CFD is a patient-specific approach for a quantitative evaluation of fluid dynamics parameters and local ventilation providing additional information with respect to current clinical approaches.
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  • 文章类型: Case Reports
    Unrecognized intrathoracic gastric volvulus can be a life-threatening condition, especially in elderly individuals undergoing major surgical procedures. We herein report the first case of a gastric volvulus after a robot-assisted left upper lobectomy for non-small-cell lung cancer in a patient with a known paraesophageal hernia. The operative procedure was performed by Dr Jacques Fontaine a senior thoracic surgeon at Moffitt Cancer Center in Tampa Florida a major academic institution. This operation was complicated by a large type-III hiatal hernia, with most of the stomach having herniated into the left pleural cavity and demonstrating organo-axial torsion one day after the indexed operation for the lung cancer. The patient required emergency surgery due to gastric ischemia. The patient underwent exploratory laparotomy with reduction of the volvulus and closure of the esophageal hiatus at that time. The patient was taken back to the operating room for a planned relook 24 h after the exploratory laparotomy to assess viability of the stomach. Unfortunately, the second look revealed necrotic areas of the stomach, which required to be resected. Given her age and poor nutritional status, we elected to place a feeding jejunostomy tube. Her postoperative course was marred by an abdominal wound infection treated with a wound vacuum-assisted closure device. Ultimately she was discharged home on POD#19 tolerating a regular diet. This case report highlights that in the elderly patients undergoing left lung resection with a known large hiatal hernia, the index of suspicion for herniation must be high and prompt recognition can avert mortality or morbidity.
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  • 文章类型: Case Reports
    我们的两名患者的临床过程强调了将静脉静脉体外膜氧合(ECMO)与肝素一起用于需要胸外科手术的多外伤患者的可行性。需要进一步研究以确定是否可以使用完全无肝素的vv-ECMO进行手术。所有ICU团队都应该熟悉这项技术。
    The clinical course of our two patients highlights the feasibility of using venovenous extracorporeal membrane oxygenation (ECMO) with heparin for multitraumatic patients needing thoracic surgery. Further research is required to determine if surgery can be performed with totally heparin-free vv-ECMO. All ICU teams should become familiar with this technique.
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  • Postoperative cerebral embolism after left upper or lower lobectomy caused by the thrombus in the pulmonary vein stump (PVS) is a rare complication. However, it is still unclear how the cerebral embolism develop after lobectomy, and how can we prevent further embolism after thrombus removal. We present a case of a 55-year-old man without cardiovascular disease history suffering cerebral embolism 2 days after left upper lobectomy. Patient underwent endovascular thrombectomy and discharged hospital 10 days later with proper recovery. No thrombus was detected in an enhanced pulmonary CT after 1 month of aspirin intake, but the length of PVS was measured.
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  • 文章类型: Case Reports
    BACKGROUND: Pulmonary sclerosing hemangioma (PSH) is a rare tumor that usually develops in middle-aged Asian women. PSH has four histological types (hemorrhagic, sclerotic, solid, and papillary) and often grows slowly in a lower lobe of the lung. Preoperative misdiagnosis frequently occurs because of the absence of specific clinical manifestations and imaging findings. Few reports have described PSH in women of advanced age. Case presentation: A 75-year-old woman presented to our hospital in China with a 5-day history of productive cough and intermittent hemoptysis. Computed tomography indicated bronchiectasis and a large mass in the left inferior lobe of the lung. Treatment of the bronchiectasis provided no symptom relief. The hemoptysis resolved following left lower pulmonary lobectomy, and PSH was pathologically diagnosed following surgery. At the time of this writing (after 6 months of follow-up), the tumor had not recurred, no metastases had been detected, and close follow-up was ongoing.
    CONCLUSIONS: Both bronchiectasis and PSH can cause hemoptysis. This case demonstrates that PSH should be included as a differential diagnosis of hemoptysis in women of advanced age. For patients with chronic hemoptysis, the diagnosis of PSH should be considered if the therapeutic effect of bronchiectasis is poor.
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