pterygium

翼状胬肉
  • 文章类型: Case Reports
    目的:本研究的目的是评估Viscoll胶原膜(VCM)用于板层角膜移植术。
    方法:一名54岁的4级复发性翼状胬肉患者使用VCM作为移植材料进行板层角膜移植术。标准角膜移植术后治疗,包括局部抗生素-皮质类固醇和人工泪液,被管理。
    结果:手术4天后获得完整的移植物上皮化。在9个月时的随访显示,翼状胬肉没有复发,并且VCM移植物可以很好地整合到周围组织中,并保持透明度。
    结论:该病例表明,VCM具有作为人类供体角膜替代板层角膜移植术的巨大潜力;然而,VCM在板层角膜移植术中的应用仍需进一步评估。
    OBJECTIVE: The aim of this study was to evaluate Viscoll collagen membrane (VCM) for lamellar keratoplasty.
    METHODS: A 54-year-old man with grade 4 recurrent pterygium underwent lamellar keratoplasty using VCM as the graft material. Standard keratoplasty postoperative treatments, including topical antibiotic-corticosteroid and artificial tears, were administered.
    RESULTS: Complete graft epithelialization was achieved after 4 days of the surgery. Follow-up at 9 months showed no pterygium recurrence as well as good integration of the VCM graft into the surrounding tissues with preserved transparency.
    CONCLUSIONS: This case demonstrated that VCM possesses great potential as an alternative to the human donor cornea for lamellar keratoplasty; however, the application of VCM for lamellar keratoplasty still needs additional evaluation.
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  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    已确定春季角膜结膜炎(VKC)在热带气候地区的国家中非常普遍。然而,在该地区进行的研究中,很少有证据支持这一说法。
    确定加纳临床队列中VKC的患病率和危险因素。
    一项为期3年的病例对照研究是在一家三级眼科护理机构进行的,我们回顾了2018年至2021年间诊断为VKC的患者的医疗记录.
    回顾了3800例患者的病历。确定了约359例VKC,人群患病率为9.45%。男性占VKC人口的57.1%,男女比例为1.33:1。该疾病在儿童(≤17岁)中更为普遍(40.8%),随着年龄单位的增长,总体发病率下降了10%。年龄和性别调整模型显示圆锥角膜之间存在显著正相关[aOR=40.760,95%CI-5.948至339.937],鼻炎[cOR=5.183,95%CI-2.074至12.022]和VKC。然而,VKC在翼状胬肉病例中的表达相对较低[cOR=0.315,95%CI-0.077~0.846].
    VKC在儿童中非常普遍,并且通常与特应性起源的合并症有关,这些合并症加剧了该疾病在该脆弱人群中的影响。临床医生必须为VKC儿童提供全面护理。
    UNASSIGNED: Vernal Keratoconjunctivitis (VKC) has been determined to be highly prevalent in countries within the tropical climate region. However, little evidence from studies conducted within this region has been put forward to support this claim.
    UNASSIGNED: To determine the prevalence and risk factors of VKC among a Ghanaian clinical cohort.
    UNASSIGNED: A 3-year case-control study was conducted in a tertiary eye care institution, and medical records of patients who had been diagnosed of VKC between 2018 and 2021 were reviewed.
    UNASSIGNED: Medical records of 3800 patients were reviewed. Some 359 cases of VKC were identified, with a population prevalence rate of 9.45%. Males comprised 57.1% of the population with VKC, with a male-to-female ratio of 1.33:1. The disease was more prevalent (40.8%) in children (≤17 years), and the overall odds of incidence decreased by 10% for a unit increase in age. Age and sex-adjusted models revealed significant positive associations between Keratoconus [aOR = 40.760, 95% CI -5.948 to 339.937], Rhinitis [cOR = 5.183, 95% CI -2.074 to 12.022] and VKC. However, the incidence of VKC was relatively less expressive among pterygium cases [cOR = 0.315, 95% CI -0.077 to 0.846].
    UNASSIGNED: VKC is highly prevalent among children and is often associated with comorbidities of atopic origin that exacerbate the impact of the disease among this vulnerable population. It is imperative that clinicians provide holistic care for children with VKC.
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  • 文章类型: Case Reports
    背景:翼状胬肉是一种常见的眼表疾病。翼状胬肉合并角膜穿孔少见。
    方法:一名28岁的女性患者因视力模糊突然发作和左眼流泪增加而到我们的门诊就诊。右眼视力为1.0OD,眼压(IOP)为19.5mmHg,前后段无明显异常。她的左眼视力为0.06,眼压为6.2mmHg。在鼻子下方的左眼中看到三角形血管膜组织,长入角膜,未触及瞳孔区域。裂隙灯检查显示病变区域8点位置有一个微小的圆形角膜穿孔。医院诊断为翼状胬肉合并角膜穿孔。患者接受左氧氟沙星滴眼液和自体血清滴眼液治疗。
    结论:我们报告一例翼状胬肉合并角膜穿孔的罕见病例。穿孔是翼状胬肉非常罕见的并发症。该患者接受了适当的治疗,效果良好。本文旨在提高临床医师对翼状胬肉的认识。
    BACKGROUND: Pterygium is a common ocular surface disease. Pterygium combined with corneal perforation is rare.
    METHODS: A 28-year-old female patient visited our outpatient clinic due to sudden onset of blurred vision and increased tearing in her left eye. The visual acuity was 1.0 OD and intraocular pressure (IOP) of 19.5 mmHg for the right eye with no significant abnormalities found in the anterior and posterior segments. The visual acuity of her left eye was 0.06, and IOP was 6.2 mmHg. A triangular vascular membranous tissue was seen in her left eye below the nose growing into the cornea and the pupil area was not touched. Slit-lamp examination revealed a tiny round corneal perforation in 8 o\'clock position of the lesion area. Hospital diagnosis was given as pterygium combined with corneal perforation. The patient was treated with levofloxacin eye drops and autologous serum-based eye drops.
    CONCLUSIONS: We report a rare case of pterygium combined with corneal perforation. Perforation is a very rare complication of pterygium. This patient received proper treatment and good result was seen. This article aimed to improve clinicians\' understanding of pterygium.
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  • 文章类型: English Abstract
    Lamellar keratoplasty is the most effective and safe method of surgical treatment of recurrent pterygium, providing restoration of the corneal frame and optical properties and a high anti-relapse effect due to the barrier properties of the lamellar graft. However, potential postoperative changes in the regularity of the anterior and posterior surfaces of the cornea (especially in case of advanced stage of fibrovascular tissue growth) do not always allow achieving high functional results of treatment. The article presents a clinical case that demonstrates the effectiveness and safety of excimer laser correction of refractive disorders after surgical treatment of pterygium.
    Послойная кератопластика является наиболее эффективным и безопасным методом хирургического лечения рецидивирующего птеригиума, обеспечивающим восстановление каркасных и оптических свойств роговицы, а также обусловливающим высокий противорецидивный эффект благодаря барьерным свойствам послойного трансплантата. Однако потенциальные послеоперационные изменения регулярности передней и задней поверхности роговицы (особенно в случае далекозашедшего роста фиброваскулярной ткани) не всегда позволяют достичь высоких функциональных результатов лечения. Представлено клиническое наблюдение, свидетельствующее об эффективности и безопасности выполнения эксимерлазерной коррекции рефракционных нарушений после хирургического лечения птеригиума.
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  • 文章类型: Case Reports
    背景:翼状胬肉的治疗取决于翼状胬肉的分级和临床表现(发炎或静止),手术切除是翼状胬肉超出角膜缘的最终治疗选择。感染性角膜炎是近年来最常见的并发症之一。据我们所知,目前文献中还没有描述翼状胬肉手术后的克雷伯菌角膜炎。这里,我们报道了一例翼状胬肉手术切除后角膜溃疡形成的患者。
    方法:一名62岁的女性出现疼痛,视力模糊,她左眼畏光发红一个月.她两个月前有翼状胬肉手术切除史。裂隙灯检查显示结膜充血,有中央上皮缺损的中央白色角膜溃疡,还有hypopyon.角膜刮片样品显示多药耐药(MDR)肺炎克雷伯菌,发现该菌株对头孢西丁和环丙沙星敏感。前房内注射头孢呋辛(1mg/0.1mL),强化头孢呋辛眼用混悬液(50mg/mL)和莫西沙星眼用混悬液(0.5%)成功控制感染。由于残留的中央基质混浊仍然持续存在,最终视力没有改善超过手指计数两米。
    结论:克雷伯菌角膜炎是翼状胬肉切除术后一种罕见且危及视力的并发症。本报告强调翼状胬肉手术后密切随访检查的重要性。
    BACKGROUND: Management of pterygium is dependent on the grading of pterygium and its clinical presentation (inflamed or quiescent), and surgical excision is the final choice of treatment for the pterygium extending beyond the limbus. Infectious keratitis is one of the most commonly reported complications in recent years. To the best of our knowledge, Klebsiella keratitis after pterygium surgery has not been described in the current literature. Here, we report a patient with corneal ulcer formation following pterygium surgical excision.
    METHODS: A 62-year-old woman presented with complaints of pain, blurred vision, photophobia and redness in her left eye for a month. She had a history of pterygium surgical excision two months ago. Slit-lamp examination showed conjunctival congestion, a central whitish corneal ulcer with a central epithelial defect, and hypopyon. Corneal scraped sample revealed multidrug resistant (MDR) Klebsiella pneumonia and the strain was found to be sensitive to cefoxitin and ciprofloxacin. Intracameral cefuroxime (1 mg/0.1 mL) injection, fortified cefuroxime ophthalmic suspension (50 mg/mL) and moxifloxacin ophthalmic suspension (0.5%) were successfully administered to control the infection. Since residual central stromal opacification remained persistent, final visual acuity did not improve beyond finger counting at two meters.
    CONCLUSIONS: Klebsiella keratitis is a rare and sight-threatening complication following pterygium excision. This report emphasizes the importance of close follow-up examination following pterygium surgeries.
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  • 文章类型: Case Reports
    背景:丝裂霉素C已在各种程序中辅助使用,包括翼状胬肉切除.伤口愈合延迟,丝裂霉素C的长期并发症,可能会在几年后发生,并且很少会导致随后的无意过滤泡。然而,未报道使用丝裂霉素C后,相邻手术伤口重新开放时结膜气泡形成。
    方法:一名91岁的泰国妇女26年前接受了翼状胬肉切除术,辅以丝裂霉素C,以及同年顺利的白内障囊外摘除术。大约25年后,患者出现了没有青光眼手术或外伤的滤过泡。前节眼相干断层扫描显示了在巩膜骨刺处的气泡和前房之间连接的瘘管。观察到气泡没有进一步处理,因为没有低眼压或大泡相关的并发症发生。建议了气泡相关感染的症状/体征。
    结论:这是一例丝裂霉素C应用的罕见新并发症。手术伤口重新开放形成结膜泡,这与以前丝裂霉素C的使用有关,可能会在几十年后发生。
    BACKGROUND:  Mitomycin C has been used adjunctively in various procedures, including pterygium excision. Delayed wound healing, the long-term complication of mitomycin C, can occur several years later and may rarely cause a subsequent inadvertent filtering bleb. However, conjunctival bleb formation from the reopening of an adjacent surgical wound after mitomycin C use has not been reported.
    METHODS: A 91-year-old Thai woman had undergone pterygium excision 26 years ago, with adjunctive mitomycin C, as well as an uneventful extracapsular cataract extraction in the same year. The patient developed a filtering bleb without glaucoma surgery or trauma approximately 25 years later. Anterior segment ocular coherence tomography illustrated a fistula connected between the bleb and anterior chamber at the scleral spur. The bleb was observed without further management, as no hypotony or bleb-related complications occurred. The symptoms/signs of bleb-related infection were advised.
    CONCLUSIONS:  This is a case report of a rare novel complication of mitomycin C application. Conjunctival bleb formation from the reopening of surgical wound, which was related to the previous mitomycin C use, could occur after a few decades.
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  • 文章类型: Journal Article
    未经证实:翼状胬肉是一种良性结膜纤维血管肿瘤,逐渐侵犯角膜,它会导致角膜变形和散光,或加重预先存在的生理散光,定义为≤0.50D,不需要光学校正。翼状胬肉的根治性治疗是单纯手术,结膜角膜缘移植术和结膜自体移植术成为首选的手术技术。该研究的主要目的是调查翼状胬肉手术是否不会使术前生理性散光恶化。
    UNASSIGNED:这是一项在拉巴特穆罕默德五世军事医院眼科进行的为期12个月的前瞻性队列研究,包括43例II/III/IV期翼状胬肉,由同一位外科医生通过结膜自体移植进行手术。首先,我们研究了翼状胬肉手术与散光变化之间的关联.对于定量变量,我们使用Wilcoxon检验。在第二步中,我们根据术前散光≤0.5D或>0.5D的值将文件分为两个不同的组,以检测翼状胬肉手术对生理散光的影响。通过比较这些特征的分布对数据进行统计分析。
    未经证实:中位散光为1D(0.25;2.50)。我们人群中有35%的术前散光≤0.5D。Wilcoxon检验显示术前和术后散光之间存在统计学上的显着差异(p=0.001)。配对样本T检验显示生理性散光人群的术前和术后结果无统计学差异(p=0.53)。
    UNASSIGNED:许多研究表明翼状胬肉切除对散光的益处,但是很少有研究指出这种手术对生理性散光的影响。我们的研究表明,翼状胬肉手术不会改变生理性散光。
    UNASSIGNED: Pterygium is a benign conjunctival fibrovascular neoformation progressively encroaching on the cornea, it can cause corneal distortion and induce astigmatism, or aggravate pre-existing physiological astigmatism, which is defined as ≤ 0.50 D and not requiring optical correction. The radical treatment of pterygium is purely surgical, with conjunctivo-limbal grafting and conjunctival autografting emerging as the surgical techniques of choice. The main objective of the study was to investigate whether pterygium surgery does not worsen the preoperative physiological astigmatism.
    UNASSIGNED: This is a prospective cohort study conducted in the ophthalmology department of the Mohammed V Military Hospital in Rabat over a period of 12 months, including 43 stage II/III/IV pterygia that were operated on by conjunctival autograft by the same surgeon. First, we looked for an association between pterygium surgery and variations in astigmatism. For quantitative variables we used the Wilcoxon test. In a second step we split the file into two distinct groups according to the value of preoperative astigmatism≤ 0.5 D or >0.5 D in order to detect the impact of pterygium surgery on physiological astigmatism. Statistical analysis of the data was performed by comparing the distribution of these characteristics.
    UNASSIGNED: The median astigmatism was 1 D (0.25; 2.50). 35% of our population had preoperative astigmatism ≤0.5 D. The Wilcoxon test showed that there was a statistically significant difference between preoperative and postoperative astigmatism (p = 0.001). The paired sample T-test showed no statistically significant difference between the preoperative and postoperative outcome in the physiological astigmatism population (p = 0.53).
    UNASSIGNED: Many studies have shown the benefits of pterygium excision on astigmatism, but few studies have specified the impact of this surgery on physiological astigmatism. Our study showed that pterygium surgery does not alter physiological astigmatism.
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  • 文章类型: Case Reports
    手术诱发的坏死性巩膜炎(SINS)是一种免疫介导的疾病,在眼部手术后很少发生,潜伏期为数天至数年。我们介绍了一例49岁的男子,他在结膜自体移植的双侧翼状胬肉切除后两周出现双侧SINS。他接受了一个疗程的口服泼尼松龙治疗,局部抗生素软膏,局部非甾体抗炎药和润滑剂,密切随访和风湿病咨询。
    Surgically induced necrotizing scleritis (SINS) is an immune-mediated condition that rarely occurs after ocular surgeries with a latency period of days to years. We present a case of a 49-year-old man who developed bilateral SINS two weeks after uneventful bilateral pterygium excision with conjunctival autografts. He was managed with a course of oral prednisolone, topical antibiotic ointment, topical non-steroidal anti-inflammatory drugs and lubricants, and close follow-up and rheumatological consultation.
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  • 文章类型: Journal Article
    背景:我们描述了翼状胬肉手术后巩膜变薄的处理,这是一种罕见的并发症;此外,我们回顾了文献中发表的类似病例.
    方法:一名48岁女性在翼状胬肉切除手术后第一周出现巩膜变薄。保守治疗是管理的第一线。两个星期没有好转,所以我们决定做一个旋转皮瓣。我们通过排除其他病因来诊断巩膜dellen。该条件已成功管理,变薄的巩膜完全愈合。观察到巩膜和结膜重新铺面。
    UNASSIGNED:巩膜是翼状胬肉术后早期和罕见的并发症。在排除巩膜变薄的其他原因后确认诊断。它的确切病理生理学尚未确定,许多作者在他们发表的案例中描述了可能的解释。我们对类似案件的管理进行了全面审查。
    结论:巩膜干燥是翼状胬肉手术后罕见的并发症,它的诊断取决于排除。管理可以是保守的。然而,如果没有发现进展,请不要犹豫手术关闭。
    BACKGROUND: We describe the management of a scleral thinning after uneventful pterygium surgery, it is an uncommon complication; in addition, we have reviewed similar published cases in the literature.
    METHODS: A 48-year-old woman presented with thinning sclera in the first week after pterygium excision surgery. Conservative treatment was the first line in the management. There was no improvement for two weeks, so we decided to do a rotational flap. We put a scleral dellen diagnosis by excluding other etiologies. The condition was successfully managed, the thinning sclera healed completely. Scleral and conjunctival re-surfacing was observed.
    UNASSIGNED: Scleral dellen is an early and rare postoperative complication after pterygium surgery. The diagnosis is confirmed after excluding other causes of scleral thinning. The exact pathophysiology of it is not determined yet, many authors described probable explanation in their published cases. We did a comprehensive review of similar cases with their management.
    CONCLUSIONS: Scleral dellen is uncommon complication after pterygium surgery, its diagnosis depends on exclusion. The management can be conservative. However, if no progression was detected do not hesitate going for surgical closure.
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