UNASSIGNED:术后认知功能障碍(POCD)是一种并发症,主要发生在成年患者中,是指麻醉和手术后认知功能的新发下降。文献缺乏有关无阿片类药物麻醉及其对术后心理功能影响的证据。
UASSIGNED:无阿片类药物麻醉对泌尿外科手术后POCD的影响以前没有报道过。因此,我们介绍了15例成人患者在全身麻醉下使用右美托咪定无阿片类药物方案行经尿道泌尿外科手术,氯胺酮,还有利多卡因.
UNASSIGNED:包括在无阿片类药物全身麻醉下接受简单经尿道选择性泌尿外科手术的患者。该病例系列是关于无阿片类药物麻醉的前瞻性临床研究的一部分,并作为试点样本。小型精神状态检查(MMSE)测试,术前和术后12小时进行,用于评估POCD。
UNASSIGNED:15名平均年龄68岁的患者被纳入研究。无阿片类药物的方案与较小的泌尿外科手术后MMSE测试的无统计学意义的变化有关。
未经批准:在我们的研究中,无阿片类药物的全身麻醉方案,使用右美托咪定的混合物,氯胺酮,和利多卡因,似乎对接受经尿道泌尿外科手术的患者的术后认知功能没有负面影响。为了进一步证明这种效果,当然需要专门设计用于识别这种效果的进一步研究。
UNASSIGNED: Postoperative cognitive dysfunction (POCD) is a complication that mainly occurs in adult patients and refers to a new-onset decline in cognitive function after anesthesia and surgery. The literature lacks evidence regarding opioid-free anesthesia and its impact on mental function postoperatively.
UNASSIGNED: The effect of opioid-free anesthesia on POCD following urological surgery has not been previously reported. Accordingly, we present a
case series of 15 adult patients undergoing transurethral urological surgery under general anesthesia using an opioid-free protocol with dexmedetomidine, ketamine, and lidocaine.
UNASSIGNED: Patients that underwent simple transurethral elective urological procedures under general opioid-free anesthesia were included. This
case series is part of a prospective clinical study regarding opioid-free anesthesia and served as a pilot sample. The mini-mental state examination (MMSE) test, performed preoperatively and 12 hours postoperatively, was applied to assess POCD.
UNASSIGNED: Fifteen patients with a mean age of 68 years old were included in the study. The opioid-free protocol was associated with non-statistically significant changes of the MMSE test after minor urological procedures.
UNASSIGNED: In our study, an opioid-free protocol of general anesthesia, using a mixture of dexmedetomidine, ketamine, and lidocaine, did not seem to have a negative impact on postoperative cognitive function in patients undergoing transurethral urological surgery. Further studies specifically designed to identify this effect are certainly required to further prove such an effect.