术后认知功能障碍(POCD)和术后谵妄(POD)是常见的术后并发症,通常会导致住院时间延长,生活质量下降,医疗费用增加,增加患者死亡率。我们进行了一项荟萃分析,以评估术前认知功能训练对术后认知功能的影响。
■PubMed,科克伦图书馆,Embase,WebofScience,临床试验,中国国家知识基础设施,万方数据库,VIP数据库,和中国生物医学文献数据库检索随机对照试验,比较术前认知功能训练和常规术前措施对术后认知功能的影响。搜索期从数据库的建立到2023年3月31日。主要结果是POCD和POD的发生率。
■纳入11项随机对照试验,涉及1,045例患者。荟萃分析的结果表明,与对照组相比,术前认知功能训练可显著降低POCD的发生率(RR=0.38,P<0.00001),POD发生率差异无统计学意义(P=0.3)。认知功能训练组术后认知功能评分较对照组明显改善(MD=1.92,P=0.001)。此外,两项研究报告认知训练组中10%的患者完成了预设的训练持续时间.
■认知功能训练可显著降低POCD的发生率;POD发生率差异无统计学意义。术前认知功能训练应作为一项简单、经济,改善术后认知功能的实用方法。
■https://www.crd.约克。AC.uk/PROSPERO/display_record。php?RecordID=396154。
UNASSIGNED: Postoperative cognitive dysfunction (POCD) and postoperative delirium (POD) are common post-surgical complications that often lead to prolonged hospitalization, reduced quality of life, increased healthcare costs, and increased patient mortality. We conducted a meta-analysis to evaluate the effects of preoperative cognitive function training on postoperative cognitive function.
UNASSIGNED: PubMed, Cochrane Library, Embase, Web of Science, ClinicalTrials, China National Knowledge Infrastructure, Wanfang Database, VIP Database, and Chinese Biomedical Literature Database were searched for randomized controlled trials comparing the effects of preoperative cognitive function training and conventional preoperative measures on postoperative cognitive function. The search period spanned from the establishment of the databases to March 31, 2023. The primary outcomes were the incidence of POCD and POD.
UNASSIGNED: Eleven randomized controlled trials involving 1,045 patients were included. The results of the meta-analysis showed that, compared to the control group, preoperative cognitive function training significantly reduced the incidence of POCD (RR = 0.38, P < 0.00001), and there was no statistically significant difference in the incidence of POD (P = 0.3). Cognitive function training significantly improved postoperative cognitive function scores compared with the control group (MD = 1.92, P = 0.001). In addition, two studies reported that 10% of the patients in the cognitive training group completed a pre-set training duration.
UNASSIGNED: Cognitive function training significantly reduced the incidence of POCD; however, there was no significant difference in the incidence of POD. Preoperative cognitive function training should be promoted and emphasized as a simple, economical, and practical method of improving postoperative cognitive function.
UNASSIGNED: https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=396154.