我们介绍了英国性健康和HIV协会关于性暴露后HIV暴露后预防(PEPSE)的最新指南。本文档包括对当前数据的审查,以支持PEPSE的使用,考虑如何计算潜在暴露后的感染风险,并提供了关于何时应该和不应该考虑PEPSE的建议。我们还回顾了哪些药物用于PEPSE,提供初步评估清单,并为监测接受PEPSE的个人提出建议。特殊场景,PEPSE的成本效益,并讨论了与服务提供有关的问题。在整个文件中,考虑了PEPSE在其他艾滋病毒预防策略的更广泛背景下的位置。
We present the updated British Association for Sexual Health and HIV
guidelines for HIV post-exposure prophylaxis following sexual exposure (PEPSE). This document includes a review of the current data to support the use of PEPSE, considers how to calculate the risks of infection after a potential exposure, and provides recommendations on when PEPSE should and should not be considered. We also review which medications to use for PEPSE, provide a checklist for initial assessment, and make recommendations for monitoring individuals receiving PEPSE. Special scenarios, cost-effectiveness of PEPSE, and issues relating to service provision are also discussed. Throughout the document, the place of PEPSE within the broader context of other HIV prevention strategies is considered.