目的:在1999年至2020年期间,在美国,使用多期死亡方法分析了与风湿性多肌痛(PMR)相关的死亡率和主要死亡原因。
方法:我们分析了来自疾病控制和预防中心(CDC)数据分析系统的死亡率数据,并根据国际疾病和相关健康问题统计分类(ICD-10)类别代码选择了将PMR列为死因的死亡证明。相关死亡率,分析了死亡人数和历史趋势。使用Excel2010版本制作了与PMR相关的死亡人数和年龄标准化死亡率(ASMR)趋势图,并添加了趋势线。
结果:在过去的22年里,在美国,与PMR相关的死亡总数为15,421名妇女(89.8%),男女比例约为1:9。当PMR被列为死亡的根本原因时,女性和男性的ASMR(每10万人)约为1.8-5.1:1,当它被列为非潜在死亡原因时,它是1.8-3.3:1。PMR死亡在70岁及以上的人群中更为常见,80岁及以上的患者受影响最大。在不同的种族中,死亡人数最多的是高加索人,其次是黑人或非裔美国人。当涉及到死亡原因时,心脏病仍然排在第一位,其次是癌症。此外,我们还发现,当PMR与恶性肿瘤合并为多种死亡原因时,女性死亡人数高于男性死亡人数,两者的总死亡人数呈上升趋势,两者的总体ASMR均呈下降趋势。
结论:在过去的22年里,我们观察到美国PMR的死亡率较低.然而,对于PMR患者,尤其是老年妇女,医务人员应保持警惕并注意它们是否合并其他并发症,如恶性肿瘤,及时诊断和治疗,进一步降低PMR患者的死亡率。
OBJECTIVE: Multicause-of-death methods were used to analyze mortality and leading causes of death associated with polymyalgia rheumatica (PMR) in the United States from 1999 to 2020.
METHODS: We analyzed mortality data from the Centers for Disease Control and Prevention (CDC) Data analysis system and selected death certificates that listed PMR as the cause of death based on the International Statistical Classification of Diseases and Related Health Problems (ICD-10) category code. Relevant mortality rates, number of deaths and historical trends were analyzed. The number of PMR-related deaths and age-standardized mortality rate (ASMR) trend charts were made using Excel 2010 version and trend lines were added.
RESULTS: Over the last 22 years, the total number of PMR-related deaths in the United States was 15,421 women (89.8%), a ratio of about 1:9 men to women. When PMR is listed as the underlying cause of death, the ASMR for women and men (per 100,000 people) is approximately 1.8-5.1:1, and when it is listed as the non-underlying cause of death, it is 1.8-3.3:1. PMR deaths are more frequent in individuals aged 70 years and above, with patients aged 80 years and above being most affected. Among different ethnicities, the highest number of deaths was found in Caucasians, followed by Black or African American. When it comes to causes of death, heart disease still ranks first, followed by cancer. In addition, we also found that when PMR combined with malignant tumors as a multiple cause of death, the number of female deaths was higher than that of male deaths, the overall number of deaths of both showed an upward trend, and the overall ASMR of both showed a downward trend.
CONCLUSIONS: In the past 22 years, we have observed a low mortality rate of PMR in the United States. However, for patients with PMR, especially elderly women, medical workers should be vigilant and pay attention to whether they are combined with other complications, such as malignant neoplasms, and make timely diagnosis and treatment to further reduce the mortality rate of patients with PMR.