■这是一项系统评价和荟萃分析,比较了手术切除与经皮超声引导下真空辅助切除(US-VAE)治疗良性叶状肿瘤(PT),以局部复发(LR)为终点。
■为了确定超声引导下真空辅助切除术(US-VAE)后良性叶状肿瘤(PT)的局部复发(LR)频率与手术切除后LR的频率。
一项系统评价和荟萃分析[遵循系统评价和荟萃分析的首选报告项目(PRISMA)标准]通过比较18岁以上接受US-VAE良性PT治疗的女性的LR与至少12个月随访的局部手术切除的LR。从PubMed检索的研究,Scopus,WebofScience,和Embase。使用的合并效应测量是复发的比值比(OR)。
■1992年1月1日至2022年1月10日发表的五项比较性前瞻性或回顾性观察性研究符合选择标准,比较了手术切除与经皮US-VAE治疗良性PTLR。四个是回顾性观察队列,一个是前瞻性观察队列.共对778名妇女进行了随访。其中,439例(56.4%)接受了局部手术切除,339例(43.6%)患者患有US-VAE。5项研究中患者的中位年龄为33.7至39岁;中位尺寸为1.5厘米至3.0厘米,中位随访时间为12个月至46.6个月.针头规格范围为7G至11G。US-VAE和手术切除的LR率无统计学意义(339中的41例与439中的34例;OR1.3;p=0.29)。
■这项荟萃分析表明,使用US-VAE去除良性PT不会增加局部区域复发,并且是一种安全的微创治疗选择。
■https://www.crd.约克。AC.英国/普华永道/,标识符CRD42022309782。
UNASSIGNED: This is a systematic
review and meta-analysis comparing surgical excision with percutaneous ultrasound-guided vacuum-assisted excision (US-VAE) for the treatment of benign phyllodes tumor (PT) using local recurrence (LR) as the endpoint.
UNASSIGNED: To determine the frequency of local recurrence (LR) of benign phyllodes tumor (PT) after ultrasound-guided vacuum-assisted excision (US-VAE) compared to the frequency of LR after surgical excision.
UNASSIGNED: A systematic
review and meta-analysis [following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standard] was conducted by comparing LR in women older than 18 years treated for benign PT by US-VAE compared with local surgical excision with at least 12 months of follow-up. Studies were retrieved from PubMed, Scopus, Web of Science, and Embase. The pooled effect measure used was the odds ratio (OR) of recurrence.
UNASSIGNED: Five comparative prospective or retrospective observational studies published between January 1, 1992, and January 10, 2022, comparing surgical excision with percutaneous US-VAE for LR of benign PT met the selection criteria. Four were retrospective observational cohorts, and one was a prospective observational cohort. A total of 778 women were followed up. Of them, 439 (56.4%) underwent local surgical excision, and 339 (43.6%) patients had US-VAE. The median age of patients in the five studies ranged from 33.7 to 39 years; the median size ranged from 1.5 cm to 3.0 cm, and the median follow-up ranged from 12 months to 46.6 months. The needle gauge ranged from 7G to 11G. LR rates were not statically significant between US-VAE and surgical excision (41 of 339 versus 34 of 439; OR 1.3; p = 0.29).
UNASSIGNED: This meta-analysis suggests that using US-VAE for the removal of benign PT does not increase local regional recurrence and is a safe minimally invasive therapeutic option.
UNASSIGNED: https://www.crd.york.ac.uk/prospero/, identifier CRD42022309782.