背景:前庭性偏头痛(VM)是一种以发作性眩晕为特征的常见前庭疾病。然而,在VM中,畏光与视觉触发因素之间的关系仍有待探索.我们调查了VM发作期间畏光与VM患者发作间光敏性和视觉触发头晕的相关性。
方法:我们招募了诊断为VM的患者,有或没有畏光,在中国的七个专门的眩晕和头痛诊所。还包括健康个体作为对照组。使用横断面调查设计,我们收集了与闪烁触发的光强和头晕频率有关的数据,眩光,眩光使用头痛触发敏感性和避免性问卷和眼睛疲劳。
结果:共招募了366名患者。由闪烁引起的头晕的光敏性和频率,眩光,眩光与没有畏光的患者和对照组参与者相比,在有VM和畏光的患者中观察到的眼睛疲劳显着升高(P<0.001)。光敏感性水平与闪烁引起的头晕频率之间存在显着正相关,眩光,眩光VM和畏光患者的眼睛疲劳(P<0.001)。
结论:本研究明确确立了畏光与发作间光敏性和视觉触发性头晕的正相关,强烈主张需要进一步研究基于暴露的治疗来管理VM。
背景:ClinicalTrial.gov标识符,NCT04939922,回顾性注册,2021年6月14日。
BACKGROUND: Vestibular migraine (VM) is a prevalent vestibular disorder characterized by episodic vertigo. However, the relationship between
photophobia and visual triggers in VM remains unexplored. We investigated the correlation of
photophobia during the VM attack with interictal photosensitivity and visually triggering dizziness in patients with VM.
METHODS: We enrolled patients diagnosed with VM, with or without
photophobia, across seven specialized vertigo and headache clinics in China. Healthy individuals were also included as a control group. Using a cross-sectional survey design, we collected data related to light intensity and dizziness frequency triggered by flicker, glare, and eyestrain using the Headache Triggers Sensitivity and Avoidance Questionnaire.
RESULTS: A total of 366 patients were recruited. The photosensitivity and frequency of dizziness induced by flicker, glare, and eyestrain observed in patients with VM and photophobia were significantly elevated compared with those in patients without
photophobia and control participants (P < 0.001). A significant positive correlation was observed between photosensitivity levels and dizziness frequency triggered by flicker, glare, and eyestrain in patients with VM and photophobia (P < 0.001).
CONCLUSIONS: This study unequivocally established a positive association of ictal
photophobia with interictal photosensitivity and visually triggering dizziness, strongly advocating the need for further research on exposure-based therapies for managing VM.
BACKGROUND: ClinicalTrial.gov Identifier, NCT04939922, retrospectively registered, 14th June 2021.