omentectomy

网膜切除术
  • 文章类型: Journal Article
    Omental梗塞(OI)是急性腹痛的罕见原因。OI的诊断需要高的临床怀疑指数,因为发病率低于1%。表现为腹痛。我们报告了印度一家三级医院的初级OI的临床和放射学概况。
    在这项回顾性横断面研究中,我们回顾了7年(2015-2022年)腹痛患者的电子医疗和放射学记录.系统地收集和分析变量。
    本研究共纳入22例诊断为原发性OI的患者。男性占优势(63.6%),平均年龄为47.45岁(SD±13.84;范围:18-72岁)。大多数患者属于I类肥胖(根据亚太体重指数分类),平均BMI为26.56kg/m2(SD±3.21kg/m2)。所有患者均以腹痛为主要症状,平均持续时间为8.64天(SD±10.15;范围:1-42天)。最常见的疼痛部位是右侧软骨下(27.3%)和弥漫性(27.3%),其次是右髂窝(18.1%)。大多数(95.45%,n=21/22)患者接受保守治疗,只有一个需要手术干预。
    原发性OI是一种罕见且良性的急腹症病因。肥胖是一种危险因素,但与OI的大小或严重程度无关。放射成像,比如计算机断层扫描(CT)扫描,对诊断至关重要。在考虑手术选择之前,保守的治疗路线应该是治疗原发性OI的第一种方法。
    UNASSIGNED: Omental infarction (OI) is an uncommon cause of acute abdominal pain. A high index of clinical suspicion is required for diagnosis of OI as the incidence is less than 1 %, presenting with abdominal pain. We report primary OI\'s clinical and radiological profile from a single tertiary care hospital in India.
    UNASSIGNED: In this retrospective cross-sectional study, the electronic medical and radiology records of patients with abdominal pain were reviewed over seven years (2015-2022). Variables were systematically collected and analyzed.
    UNASSIGNED: A total of 22 patients diagnosed with primary OI were included in this study. Male preponderance (63.6 %) was noted with a mean age of 47.45 years (SD ± 13.84; range: 18-72 years). Most patients belonged to class I obesity (according to the Asia-Pacific body mass index classification) with a mean BMI of 26.56 kg/m2 (SD ± 3.21 kg/m2). All patients had abdominal pain as the primary symptom, with a mean duration of 8.64 days (SD ± 10.15; range: 1-42 days). The most common locations of pain were the right hypochondrium (27.3 %) and diffuse (27.3 %), followed by the right iliac fossa (18.1 %). Most (95.45 %, n=21/22) patients were treated conservatively, and only one required surgical intervention.
    UNASSIGNED: Primary OI is a rare and benign cause of acute abdomen. Obesity is a risk factor but does not correlate with the size or severity of OI. Radiological imaging, like a computed tomography (CT) scan, is essential for diagnosis. A conservative management line should be the first approach in treating primary OI before considering surgical options.
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  • 文章类型: Systematic Review
    这篇综述概述了网膜切除术的腹部影响,有或没有腹膜外重建。总的来说,报告的并发症发生率较低。短期并发症包括肠梗阻,肠狭窄,腹部脓肿和败血症(范围0.0%-23%)。供方疝主要报告为长期并发症(高达32%),观察到可忽略不计的胃肠道并发症。然而,证据水平和方法学质量相当低,最长随访时间为8.5年.
    This review provides an overview regarding the abdominal effects of an omentectomy, with or without extra-peritoneal reconstructions. In general, reported complication rates were low. Short-term complications involved ileus, bowel stenosis, abdominal abscess and sepsis (range 0.0%-23%). Donor-site hernia was mainly reported as long-term complication (up to 32%) and negligible gastrointestinal complications were observed. However, the level of evidence and methodological quality are quite low with a maximum of 8.5 years follow-up.
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  • 文章类型: Journal Article
    探讨2型子宫内膜癌(EC)隐匿性大网膜转移的危险因素及剔除术对患者生存的影响。这项研究招募了被诊断为高风险(3级,浆液,透明细胞,未分化,癌肉瘤,或混合型)EC在2000年至2021年之间,并在我们中心接受了手术。对482例患者的数据进行回顾性分析。405例(84.0%)患者行网膜切除术。61例(12.7%)患者发生脑转移。这些转移中有18例(29.5%)是隐匿的。附体参与,恶性细胞学,腹膜扩散是大网膜转移的独立危险因素。接受网膜切除术的患者的5年总生存率(OS)为59.5%,未接受的患者为64.7%(P=0.558)。在有和没有网膜转移的患者中,总体5年OS率分别为34.9%和63.5%,分别(P<0.001)。正常网膜患者的5年OS率,肉眼肿瘤,隐匿性转移率为63.5%,26.9%,52.5%,分别(P<0.001)。在II型子宫内膜癌中,网膜转移并不少见;大约三分之一的患者有隐匿性转移。因素-细胞学阳性,附件的参与,腹膜受累与大网膜转移的可能性较高有关。
    To investigate the risk factors for occult omental metastasis and the effect of omentectomy on the survival of type 2 endometrial cancer (EC) patients. This study enrolled patients who were diagnosed with high-risk (grade 3, serous, clear cell, undifferentiated, carcinosarcoma, or mixed type) EC between 2000 and 2021 and underwent surgery in our center. Data from 482 patients were analyzed retrospectively. Omentectomy was performed in 405 (84.0%) patients. Omental metastases were detected in 61 (12.7%) patients. Eighteen (29.5%) of these metastases were occult. Adnexal involvement, malignant cytology, and peritoneal spread were independent risk factors for omental metastasis. The 5-year overall survival (OS) rate was 59.5% in patients who underwent omentectomy and 64.7% in those who did not (P = 0.558). In patients with and without omental metastases, the overall 5-year OS rates were 34.9% and 63.5%, respectively (P < 0.001). The 5-year OS rates of patients with a normal omentum, gross tumors, and occult metastases were 63.5%, 26.9%, and 52.5%, respectively (P < 0.001). Omental metastases is not uncommon in type II endometrial cancer; approximately one third of patients have occult metastases. Factors - positive cytology, adnexal involvement, and peritoneal involvement are associated with higher probability of omental metastases.
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  • 文章类型: Journal Article
    目的:非子宫内膜样子宫内膜癌(非EEC)与子宫内膜样子宫内膜癌的治疗方法不同。目的探讨非子宫内膜样子宫内膜癌大网膜疾病的预后意义和大网膜切除术的作用,并结合研究结果讨论目前的文献。
    方法:该研究包括1996年1月至2018年12月在大学医院妇科肿瘤中心接受手术治疗和随访的200,3例非EEC患者。根据是否进行网膜切除术和是否存在网膜转移,将患者分为三组。病人的人口统计,临床特征,如分期,grade,组织病理学类型,淋巴管间隙侵犯(LVSI),子宫肌层浸润,淋巴结受累,并比较两组间的生存结局.
    结果:该研究包括203名患者。25例患者(12%)有网膜转移。LVSI报告为57.3%,88.0%,43.2%的非网膜切除术,无网膜转移,和网膜转移组,分别(p=0.001)。5年无病生存率(DFS)和总生存率(OS)根据肿瘤分级,腹膜细胞学,和淋巴结清扫术也进行了比较,发现在统计学上相似。无网膜转移组5年OS率为70.6%,有网膜转移组5年OS率为16.2%,分别(p=0.001)。在网膜切除术组中,无网膜转移的5年DFS率为62.2%,有网膜转移的5年DFS率为13.0%(p=0.001)。未切除组5年OS率为86.3%,DFS率为80.0%。
    结论:在非子宫内膜样肿瘤中,未进行网膜切除术组的生存率较好.基于这些结果,我们可以说,对于术中目视检查发现网膜正常的非子宫内膜样肿瘤,可能不需要进行网膜切除术。
    Non-endometrioid endometrial cancers (non-EEC) have different management from endometrioid endometrial cancers. The purpose of this study was to investigate the prognostic significance of omental disease and the role of omentectomy in non-endometrioid endometrial cancer and discuss the current literature with the findings.
    The study included two hundred-three patients with non-EEC who underwent surgical treatment and follow-up between January 1996 and December 2018 in a University Hospital Gynecologic Oncology Center. The patients were divided into three groups according to whether omentectomy was performed and the presence of omental metastasis. The patient\'s demographics, clinical characteristics such as stage, grade, histopathologic type, lymphovascular space invasion (LVSI), myometrial invasion, lymph node involvement, and survival outcomes were compared between the groups.
    The study included 203 patients. Twenty-five patients (12%) had omental metastases. LVSI was reported in 57.3%, 88.0%, and 43.2% of the non-omentectomy, no-omental metastasis, and omental metastatic groups, respectively (p = 0.001). The 5-year disease-free survival (DFS) and overall survival (OS) rates according to the tumor grade, peritoneal cytology, and lymphadenectomy were also compared and were found to be statistically similar. The five-year OS rates were 70.6% for the group without omental metastases and 16.2% for the group with omental metastases, respectively (p = 0.001). In the group of omentectomy, the five-year DFS rates were 62.2% in cases without omental metastasis and 13.0% in cases with omental metastasis (p = 0.001). The five-year OS rates of 86.3% and DFS rates of 80.0% in the group without omentectomy.
    In non-endometrioid tumors, the survival rate was better in the group that did not undergo omentectomy. Based on these results, we can say that omentectomy may not be necessary for non-endometrioid tumors whose omentum is found to be normal in intraoperative visual examination.
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  • 文章类型: Multicenter Study
    背景:PD导管尖端迁移是常见的并发症,也是导管故障的重要原因。从这个角度来看,我们介绍了我们在新导管和新技术方面的经验,该技术涉及使用新的三袖带PD导管和低进入部位,以试图防止PD导管迁移.
    方法:在5年的时间里,在一个以上的PD中心对503例PD患者进行了研究。
    结果:在5年随访期间,我们记录的导管迁移百分比为零。其他技术并发症为引流不良,占3.4%,网膜包裹占2.8%,早期渗漏3.4%,导管置换占2.4%。在研究结束时,PD导管1年生存率为97.6%.
    结论:我们的新型三套囊PD导管和我们的低进入方法似乎在预防PD导管迁移和减少其他机械并发症方面有效。
    BACKGROUND: PD catheter tip migration is a common complication and a significant cause of catheter malfunction. In this perspective, we present our experience with a new catheter and a new technique that involves the use of a new triple cuff PD catheter and a low entry site in an attempt to prevent PD catheter migration.
    METHODS: A total of 503 incident PD patients have been studied in more than one PD center over a period of 5 years.
    RESULTS: During the 5-year follow up we recorded zero percent catheter migration. Other technical complications were poor drainage in 3.4%, omental wrap in 2.8%, early leakage in 3.4%, and catheter replacement in 2.4%. By the end of the study, the one-year PD catheter survival was 97.6%.
    CONCLUSIONS: Our new triple cuff PD catheter and our low-entry approach seem to be effective in preventing PD catheter migration and minimizing other mechanical complications.
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  • 文章类型: Journal Article
    本研究旨在确定通过经阴道自然腔道内镜手术(vNOTES)进行网膜切除术以对卵巢和高危子宫内膜恶性肿瘤进行手术分期的可行性。
    这项描述性研究是在瑞士一家非大学医院进行的。在2020年5月至2023年4月期间,通过vNOTES对18例可疑附件肿块或高危子宫内膜癌患者进行了手术分期,包括网膜下切除术。
    患者因可疑附件肿块14例(77.8%)和高危子宫内膜癌4例(22.2%)行肿瘤手术分期。所有患者均进行了vNOTES眼切除术,无并发症。相关手术包括输卵管卵巢切除术(94.4%),子宫切除术(55.6%),腹膜活检(33.3%),盆腔前哨淋巴结活检(22.2%),阑尾切除术(5.6%)。进行眼切除术的中位时间为9(4-13)分钟。所有肿瘤分期均由vNOTES完成。术中无明显并发症发生。我们观察到1例(5.6%)术后发热可能与阴道袖带感染有关(Clavien-DindoII级)。
    这项研究证明了进行vNOTES肿瘤分期的可行性,需要复杂的肾盂外手术,如网膜切除术,支持其在治疗妇科恶性肿瘤如卵巢癌和高危子宫内膜癌方面的潜在作用。然而,在将这种方法扩展到研究设置之外之前,其可行性的有力证据,实际利益,和长期的肿瘤结果是必要的。
    UNASSIGNED: This study aimed to determine the feasibility of performing omentectomy by transvaginal natural orifice transluminal endoscopic surgery (vNOTES) for surgical staging of ovarian and high-risk endometrial malignancies.
    UNASSIGNED: This descriptive study was realized in a non-university hospital in Switzerland. Eighteen patients with suspicious adnexal masses or high-risk endometrial cancer underwent surgical staging comprising infracolic omentectomy by vNOTES between May 2020 and April 2023.
    UNASSIGNED: Patients underwent oncological surgical staging for suspicious adnexal masses in 14 cases (77.8%) and high-risk endometrial cancer in 4 cases (22.2%). vNOTES omentectomies were performed in all patients without complications. Associated procedures included salpingo-oophorectomy (94.4%), hysterectomy (55.6%), peritoneal biopsies (33.3%), pelvic sentinel lymph node biopsies (22.2%), and appendectomy (5.6%). The median time to perform omentectomies was 9 (4-13) min. All oncological staging were completed by vNOTES. No significant intraoperative complications occurred. We observed 1 case (5.6%) of postoperative fever probably associated with vaginal cuff infection (Clavien-Dindo grade II).
    UNASSIGNED: This study demonstrated the feasibility of performing vNOTES oncological staging requiring complex extrapelvic procedures such as infracolic omentectomy, supporting its potential role for managing gynecological malignancies such as ovarian and high-risk endometrial cancers. However, before expanding this approach outside study settings, strong evidence of its feasibility, practical benefits, and long-term oncological outcomes are needed.
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  • 文章类型: Journal Article
    腹膜透析导管(PDC)的放置目前是儿科外科医生实践中的常见程序,对终极技术的探索永远不会停止。这项研究的目的是评估我们对腹腔镜PDC放置方法的经验,执行“2+1”(“二加一”)技术,其中\"+1\"套管针倾斜放置,穿过腹壁时指向道格拉斯袋。该隧道还用于放置和保持PDC的适当位置。
    方法:我们评估了2018年至2022年间接受腹腔镜辅助PDC置入的5名儿童的队列。
    结果:这个过程很简单,相对较快,以及PDC放置的安全技术。此外,根据我们的经验,同时进行网膜切除术是必要的,以减少由于网膜包裹引起的导管阻塞和迁移的风险。
    结论:腹腔镜方法可以改善可视化并更准确地将导管放置在腹腔内。伴随网膜切除对于防止PDC功能障碍和迁移是必要的。
    The placement of a peritoneal dialysis catheter (PDC) is currently a common procedure in pediatric surgeon practice, and the search for the ultimate technique never stops. The purpose of this study is to evaluate our experience with the laparoscopic PDC placement approach, performing a \"2+1\" (\"two plus one\") technique, where the \"+1\" trocar is placed in an oblique manner, pointing toward the Douglas pouch when passing through the abdominal wall. This tunnel is further used to place and maintain the proper position of the PDC.
    METHODS: We assessed a cohort of five children who underwent laparoscopic-assisted PDC placement between 2018 and 2022.
    RESULTS: This procedure is a simple, relatively quick, and safe technique for PDC placement. Furthermore, in our experience, concomitant omentectomy is necessary to reduce the risk of catheter obstruction and migration due to omental wrapping.
    CONCLUSIONS: The laparoscopic approach allows for improved visualization and more accurate placement of a catheter inside the abdominal cavity. Concomitant omental excision is necessary to prevent PDC malfunction and migration.
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  • 文章类型: Multicenter Study
    背景:胃癌的治疗通常包括围手术期化疗联合根治性(R0)胃切除术。除了改良的D2淋巴结肿大,建议进行完整的网膜切除术.然而,几乎没有证据表明网膜切除术对生存有益.本研究提供了OMEGA研究的后续数据。
    方法:这项多中心前瞻性队列研究纳入了100例连续胃癌患者,这些患者接受了(次)全胃切除术,包括完整的整体网膜切除术和改良的D2淋巴结切除术。本研究的主要结果是5年总生存率。比较有无网膜转移的患者。多变量回归分析检测与局部复发和/或转移相关的病理因素。
    结果:在纳入的100名患者中,5人在大网膜有转移.有网膜转移的患者的五年总生存率为0.0%,无网膜转移的患者为44.2%(p=0.001)。有或没有网膜转移的患者的中位总生存时间为7个月和53个月。在没有网膜转移的患者中,(y)pT3-4期肿瘤和血管侵袭性生长与局部复发和/或转移有关。
    结论:在接受潜在治愈性手术的胃癌患者中,大网膜转移的存在与总生存期受损相关。在未发现网膜转移的情况下,作为胃癌根治性胃切除术的一部分的网膜切除术可能不会对生存带来好处。
    BACKGROUND: Curative therapy for gastric cancer usually consists of perioperative chemotherapy combined with a radical (R0) gastrectomy. In addition to a modified D2 lymphadenectomy, a complete omentectomy is recommended. However, there is little evidence for a survival benefit of omentectomy. This study presents the follow-up data of the OMEGA study.
    METHODS: This multicenter prospective cohort study included 100 consecutive patients with gastric cancer undergoing (sub)total gastrectomy with complete en bloc omentectomy and modified D2 lymphadenectomy. Primary outcome of the current study was 5-year overall survival. Patients with or without omental metastases were compared. Pathological factors associated with locoregional recurrence and/or metastases were tested with multivariable regression analysis.
    RESULTS: Of 100 included patients, five had metastases in the greater omentum. Five-year overall survival was 0.0% in patients with omental metastases and 44.2% in patients without omental metastases (p = 0.001). Median overall survival time for patients with or without omental metastases was 7 months and 53 months. A (y)pT3-4 stage tumor and vasoinvasive growth were associated with locoregional recurrence and/or metastases in patients without omental metastases.
    CONCLUSIONS: The presence of omental metastases in gastric cancer patients who underwent potentially curative surgery was associated with impaired overall survival. Omentectomy as part of radical gastrectomy for gastric cancer might not contribute to a survival benefit in case of undetected omental metastases.
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  • 文章类型: Journal Article
    网膜切除术是细胞减灭术(CRS)的重要组成部分。然而,考虑到对损伤的恐惧,去除网膜的胃周围拱廊(PGA)是网膜切除术的一个有争议的方面,血管受损和胃轻瘫。因此,我们进行了一项研究,以评估在网膜切除术中去除PGA的必要性和效果.
    这项研究的性质是一项前瞻性观察性研究。研究期为1年,介于2019年3月至2020年2月29日之间。III至IV期浆液性上皮性卵巢癌患者-化疗初治/新辅助化疗后,没有宏观参与的PGA纳入研究.将患者分为两组-去除PGA的患者(第1组)和保留PGA的患者(第2组)。Pre,采用标准统计学方法比较两组患者的术中和术后因素。
    在第1组中36.4%的患者中存在PGA微转移。这种参与的预测因素包括大网膜移动部分的总体参与和微观参与(p<0.001),术前Meyer评分(p<0.05)和CRS期间的腹膜炎切除术要求(p<0.05),这意味着腹膜癌病的发生率更高,更多的是PGA微观参与的机会。在比较两组术后结果时,我们注意到术中时间的统计学差异(p<0.01),第1组患者恢复时间延长,重症监护病房和住院时间增加(p<0.001),尽管绝对差异很小。然而,术后主要并发症或耐受软饮食的时间无显著差异.
    在大量病例中发现了PGA微转移。去除它也是一种安全的手术,发病率最低,术后效果良好,尤其是在患有严重腹膜癌的情况下。因此,应该考虑,前提是我们要实现完全的细胞减少。
    UNASSIGNED: Omentectomy is an essential part of cytoreductive surgery (CRS). However, removal of perigastric arcade (PGA) of the omentum is a controversial aspect of omentectomy in view of the fear of injury, vascular compromise and gastroparesis. Hence, we conducted a study to evaluate the necessity and effect of removal of PGA during omentectomy.
    UNASSIGNED: The nature of the study was a prospective observational study. The study period was for 1 year between 1.3.2019 and 29.2.2020. Patients with stage III to IV serous epithelial ovarian cancers - chemo naive/post neoadjuvant chemotherapy, without macroscopic involvement of the PGA were included in the study. Patients were divided into two groups - those who had PGA removed (group 1) and those whose PGA was preserved (group 2). Pre, intra and postoperative factors between the two groups were compared using standard statistical methods.
    UNASSIGNED: Micrometastasis to PGA was present in 36.4% of the patients in group 1. The predictors for this involvement included gross involvement and microscopic involvement of the mobile part of the omentum (p < 0.001), pre surgery Meyer\'s score (p < 0.05) and requirement of peritonectomy (p < 0.05) during the CRS implying that higher the peritoneal carcinomatosis, more are the chances of microscopic involvement of PGA. On comparing postoperative outcomes between the two groups, we noted a statistically significant difference in intra-operative time (p < 0.01), prolonged recovery time with increased intensive care unit and hospital stay (p < 0.001) in group 1, although all with small absolute difference. However, there was no significant difference in major post-operative complications or time taken to tolerate soft diet.
    UNASSIGNED: Micrometastasis to PGA was noted in significant number of cases. Its removal is also a safe procedure with minimal morbidity and good postoperative outcomes especially in cases with significant peritoneal carcinomatosis. Hence, it should be considered, provided we are achieving a complete cytoreduction otherwise.
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  • 文章类型: Journal Article
    NeginePaulIntroduction传统上,胃癌切除术中完整网膜切除术的概念是基于淋巴引流和隐匿性网膜转移(OM)的发生。然而,最近出现的证据对完全网膜切除术的概念提出了挑战.我们,因此,目的了解隐匿性OM的发生率和危险因素,并评估有和无转移患者的预后。方法这是一个单一的机构,回顾性研究接受根治性胃癌根治术3年(2016年4月1日至2019年3月31日)的胃癌患者。所有患者均进行了完整的网膜切除术,并在切除的标本中解剖了网膜和淋巴结,并送去进行病理分析。从医院患者数据库中收集临床和流行病学数据并进行分析。结果共纳入185例患者,平均年龄53.84岁.185例患者中有20例患有OM(10.8%)。年龄,性别,肿瘤的位置,和新辅助化疗在预测OM方面无统计学意义。然而,发现肿瘤大小和肿瘤深度与OM显著相关.OM的发生更可能与疾病复发有关,尤其是在腹膜里.平均总生存期为38.15个月(±3.33SD),而OM患者的生存率较低,23.31个月(±7.79标准差),p值为0.012。结论T1和T2胃癌未出现OM,T3和T4肿瘤中OM的发生率约为12.7%。因此,在T1/T2早期肿瘤中可以省略完整的网膜切除术。OM与不良预后相关,腹膜复发增加,总生存率下降,尽管做了完整的网膜切除术,并可作为疾病复发和总生存期的预后指标。
    Negine PaulIntroduction  Traditionally, the concept of complete omentectomy during gastric resection for cancer was based on lymphatic drainage and the occurrence of occult omental metastasis (OM). However, recent emerging evidence has challenged this concept of complete omentectomy. We, therefore, aim to find the incidence and risk factors of occult OM and also evaluate the outcome of patients with and without such metastasis. Methods  This is a single institutional, retrospective study of patients with gastric cancer who underwent curative radical gastrectomy for a period of 3 years (April 1, 2016, to March 31, 2019). A complete omentectomy was performed in all patients and the omentum and nodal stations were dissected in the resected specimen and sent for pathological analysis. Clinical and epidemiological data were collected from the hospital patient database and analysis was done. Results  A total of 185 patients have been included in the study, with a mean age of 53.84 years. Twenty of the 185 patients had OM (10.8%). Age, sex, location of the tumor, and neoadjuvant chemotherapy were not statistically significant in predicting OM. However, tumor size and tumor depth were found to have a significant association with OM. The occurrence of OM was more likely to be associated with disease recurrence, especially in the peritoneum. The mean overall survival was 38.15 months (±3.33 SD), whereas patients with OM had lower survival, 23.31 months (±7.79 SD), with a p -value of 0.012. Conclusion  OM was not encountered in T1 and T2 gastric cancers and the incidence of OM in T3 and T4 tumors was approximately 12.7%. Therefore, complete omentectomy may be omitted in early T1/T2 tumors. OM was associated with poor prognosis, increased peritoneal recurrence, and decreased overall survival, in spite of a complete omentectomy, and may serve as a prognostic indicator for disease recurrence and overall survival.
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