糖尿病是当前快节奏文化中的主要代谢紊乱;其患病率在世界范围内和所有年龄段中都在上升。指南建议对糖尿病进行普遍筛查;然而,由于血液采集的侵入性,个体对这些测试的吸收表明了挑战。因此,有必要对糖尿病筛查进行非侵入性调查,以减少亲热,并适用于所有医疗环境.
■因此,我们根据系统评价和荟萃分析指南的首选报告项目进行了系统评价和荟萃分析,量化糖尿病与脱落细胞学高碘酸-希夫染色作为筛查方法的有效性之间的关联。MEDLINE,EMBASE,科克伦,Scopus,WebofScience,CINAHL,和谷歌学者被系统地搜索到2022年7月20日之前的出版物。选择了六项研究(病例对照横断面)并进行了深入评估。对森林地块进行统计评估,并检查了比值比和权重。
■证明了具有高碘酸-希夫(PAS)染色的脱落细胞学可用作糖尿病状态评估的筛查测试。研究结果表明,上述非侵入性测试是糖尿病患者的决定性筛查实践。
■本系统综述和荟萃分析表明,剥脱细胞学中的PAS染色可用作糖尿病个体的非侵入性筛查,以评估当前的血糖水平。鉴于全球糖尿病风险增加,更高质量的前瞻性证据建议在更大的样本量与其他代谢紊乱,种族,和口腔疾病,以进一步评估结果的合理性。
UNASSIGNED: Diabetes mellitus is a dominant metabolic disorder in the current fast paced culture; its prevalence is escalating worldwide and among all age groups. Guidelines recommend universal screening for diabetes; however, the uptake of these tests in individuals suggests challenges owing to invasive nature of blood collection. Thus, there arises the need for a
noninvasive investigation for diabetes screening with a minimum paraphilia and for all medical settings.
UNASSIGNED: We have thus conducted a systematic
review and meta-analysis according to Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines, to quantify the association between diabetes and effectiveness of periodic acid-Schiff staining of exfoliative cytology as a screening method. MEDLINE, EMBASE, Cochrane, Scopus, Web of science, CINAHL, and Google Scholar were searched systematically for publications dated till July 20, 2022. Six studies (case-control cross-sectional) were selected and evaluated in depth. The statistical evaluation was done with a forest plot with odds ratio and weightage examined.
UNASSIGNED: It was proved that exfoliative cytology with periodic acid-Schiff (PAS) staining can be used as a screening test for diabetic status evaluation. The findings suggest that the aforesaid
noninvasive test is a conclusive screening practice for diabetics.
UNASSIGNED: This systematic
review and meta-analysis suggest that PAS staining in exfoliative cytology can be used as a
noninvasive screening in diabetic individuals to assess the current level of blood glucose. Given the increased risk of diabetes worldwide, higher quality prospective evidence is suggested in larger sample sizes with other metabolic disorders, ethnicity, and oral disorders to further evaluate the plausibility of the results.