背景:全球超过17亿人受到被忽视的热带病(NTDs)的影响。受NTD影响的人口中有40%生活在非洲最贫穷的人,最脆弱的,很难到达地理区域。NTD造成了巨大的社会和经济负担,加剧了边缘化和污名化。世界卫生组织目前的NTD路线图旨在防止,control,消除,或根除20种热带病。埃塞俄比亚经历了这些疾病的沉重负担,但是目前对诊断的访问,医学,和/或护理很少被探索以告知该国的NTD战略计划。范围界定审查的总体目的是绘制和描述NTD的负担和获得诊断方面的挑战,医学,和/或在埃塞俄比亚的护理。
方法:在PubMed,科克伦图书馆,和谷歌学者从2000年1月到2022年5月,没有语言或学习设计的限制。遵循系统审查和Meta分析扩展的首选报告项目,用于筛选研究。对关键发现进行了定性提取和叙述。
结果:搜索结果为4532篇文章,其中105项符合纳入标准,并被纳入范围审查的三个主题:NTD的负担,访问诊断,药物和/或护理,和关键障碍。尽管埃塞俄比亚在预防和控制NTD方面取得了进展,负担仍然很高,以及获得诊断的进展,药物/药物,和/或护理非常缓慢。贫穷,生活质量差,NTD计划的资金不足使该国消除NTD计划的进程减速。
结论:范围审查确定了大量关于埃塞俄比亚NTDs负担和诊断策略的研究,治疗,和/或护理;然而,关于新诊断技术和药物在该国的适用性和潜在益处的证据很少。定期审查和分析此类国家一级的证据对于为国家NTD路线图和地方实施战略提供信息非常重要。
More than 1.7 billion people are affected by neglected tropical diseases (NTDs) worldwide. Forty percent of the NTD-affected people live in Africa with the poorest, most vulnerable, and hard to reach geographical areas. The NTDs cause significant social and economic burden and deepen marginalization and stigmatization. The World Health Organization\'s current roadmap for NTD aims to prevent, control, eliminate, or eradicate 20 tropical diseases. Ethiopia experiences a high burden of these diseases, but current access to diagnostics, medicine, and/or care has been little explored to inform the country\'s NTD strategic plan. The overall purpose of the scoping
review was to map and characterize the burden of NTDs and challenges in access to diagnostics, medicine, and/or care in Ethiopia.
A systematic search of evidence was conducted in PubMed, Cochrane Library, and Google Scholar from January 2000 until May 2022, without restrictions of language or study design. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping
Review was followed for screening of studies. Key findings were extracted and narrated qualitatively.
The search resulted in 4532 articles, of which 105 met the inclusion criteria and were included in the scoping
review under three themes: burden of NTDs, access to diagnostics, medicine and/or care, and key barriers. Although gains have been made in the prevention and control of NTDs in Ethiopia, the burden remains high, and progress in access to diagnostics, medicine/drugs, and/or care is very slow. Poverty, poor quality of life, and underfunding of NTD programs decelerate the process of NTD elimination program in the country.
The scoping
review identified a considerable number of studies on the burden of NTDs in Ethiopia and strategies for diagnosis, treatment, and/or care; however, there is a paucity of evidence on the suitability and potential benefits of novel diagnostic technologies and medicines in the country. A regular
review and analysis of such country-level evidence is important to inform the country NTDs roadmap and local implementation strategies.