关键词: African region Control Elimination Eradication Neglected tropical diseases Scoping review

Mesh : Humans Neglected Diseases / epidemiology prevention & control World Health Organization Ethiopia Onchocerciasis / epidemiology prevention & control Schistosomiasis Tropical Medicine

来  源:   DOI:10.1016/j.ijid.2024.01.010   PDF(Pubmed)

Abstract:
OBJECTIVE: NTDs historically receive less attention than other diseases in the same regions. Recent gap analyses revealed notable shortcomings despite NTD elimination progress. This systematic scoping review was conducted to understand NTD control, elimination, and eradication efforts in the WHO African region over the last 30 years.
METHODS: Peer-reviewed publications from PubMed, Web of Science, and Cochrane databases related to NTD control, elimination, and eradication in the WHO African Region from 1990 to 2022 were reviewed. Included articles were categorized based on NTD; study location, type, and period; and topic areas. Technical and guidance documents from WHO, UN, partner, and academic/research institutions were reviewed. Country-specific multi-year NTD master plans were documented.
RESULTS: Four hundred eighty peer-reviewed articles, six Cochrane reviews, and 134 technical reports were included. MDA and non-interventional/survey-related studies were common topics. Lymphatic filariasis, trachoma, schistosomiasis, and onchocerciasis were the most frequently studied NTDs. Tanzania, Ethiopia, and Nigeria were the most represented countries; multi-country studies were limited.
CONCLUSIONS: The review highlights progress made in NTD control, elimination, and eradication efforts in the WHO African Region and can inform national/regional strategies. Disease and geographical disparities were evident, warranting focus and research in certain countries. A standardized approach to NTD control programs is needed for sustained progress.
BACKGROUND: There was no funding source for this study.
摘要:
背景:NTDs历来比同一地区的其他疾病受到的关注少。尽管消除NTD取得了进展,但最近的差距分析显示出明显的缺点。进行了系统的范围审查,以了解NTD控制,消除,以及过去30年来世卫组织非洲区域的根除努力。
方法:来自PubMed的同行评审出版物,WebofScience,和与NTD控制相关的Cochrane数据库,消除,对世卫组织非洲区域1990年至2022年的根除情况进行了审查。纳入的文章根据NTD进行分类;研究地点,type,和时期;和主题领域。世卫组织的技术和指导文件,UN,合作伙伴,和学术/研究机构进行了审查。记录了针对特定国家的多年NTD总计划。
结果:480篇同行评审文章,六个Cochrane评论,其中包括134份技术报告。MDA和非干预/调查相关研究是共同的主题。淋巴丝虫病,沙眼,血吸虫病,盘尾丝虫病是研究最频繁的NTDs。坦桑尼亚,埃塞俄比亚,尼日利亚是代表最多的国家;多国研究有限。
结论:这篇综述突出了NTD控制方面取得的进展,消除,世卫组织非洲区域的根除努力,并可以为国家/区域战略提供信息。疾病和地理差异很明显,保证在某些国家的重点和研究。NTD控制程序的标准化方法需要持续进展。
背景:本研究没有资金来源。
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