常见的皮肤感染,如脓疱疮和sc疮,在全球范围内构成了巨大的疾病负担。在热带和资源有限的环境中特别普遍。通过大规模药物管理解决这些感染的努力最近已被证明是有效和安全的。在萨摩亚,一个太平洋岛国,这些被忽视的热带病的流行病学数据明显缺乏,或欣赏他们的司机在这个设置。
■观测,Upolu岛农村地区4至15岁儿童就读于小学的横断面调查,对萨摩亚进行了评估,以评估居住在萨摩亚农村的学童中的脓疱病和sc疮的患病率,与描述性流行病学和微生物基因组数据相结合。对从萨摩亚学童中分离出的本地金黄色葡萄球菌进行了系统发育评估,以估计推定的社区传播。
■在这项调查中,在萨摩亚学童中观察到的脓疱病患病率是全球描述的最高患病率之一(57•1%,95%CI[53•8-60•5%],476/833)。注意到活动性脓疱病与年龄和性别之间的关联,年龄较小的儿童和男性更常见(aOR2•8[1•8-4•7]和aOR1•8[1•3-2•5],分别)。sc疮的患病率与其他南太平洋岛国相似(14•4%,95%CI[12•2-17•0%],120/833)。预测了金黄色葡萄球菌的传播,主要是在同一所学校的孩子之间。化脓性链球菌的运输明显较低,在不到2%的学童中观察到咽带,与萨摩亚早期的研究一致。
■这项研究描述了萨摩亚脓疱疮和sc疮引起的相当大的疾病负担。这些发现对于解决这些条件带来的公共卫生挑战将是有价值的。提供基线流行数据,并强调在这种情况下减少相关微生物和寄生虫传播的实用策略。
■Oa\'afiagaolepa\'uifa\'ama\'iolepo\'u(脓疱病)maleutuolepa\'u(sc疮),uatelenaualefanauuamauaaiilepasefika,马勒·拉洛拉吉·阿托阿。Ofuafuagavaaimamaomapopokalameefoinaaineifaafitauli,eaofiaaileinumagaofualaauetapeinaaineifa\'ama\'i,阿利阿里·迈艾·马法伊纳·法塔玛亚·内法·马·我。EleotelenitusitusigamafaamaumaugaitotonuoSamoa,体育塔\'阿特勒内法\'阿迈奥勒帕\'u体育丽。奥娜·勒法塔瓦伊娜·内法·阿玛·我,eleoiloafo\'inimafuagamanisitulagaefaateleinaaineifa\'ama\'iolepa\'ui萨摩亚。
■Olesuesuegafaasaenisiilefanauaogailevaole4male15tausagaolooao\'ogailetulagaluainisionunu\'uituaiUpolu,Nafaatinoinaaisuesuegalea,iasuesueinaaileaotelegamafainumeraolefanauuamauaifa\'ama\'Iolepo\'u(脓疱病)maleutuolepa\'u(sc疮)。列内福·苏苏埃加,nafiailoaaifo\'ipo\'aituaigasiamaeseeseoloomauailugaopa\'umatinoolefanauaoga,inaiailoaaifoiaualauapipissiaineisiamamaileisitamaitiitiileisi,奥娜·马法瓦·艾利·奥内法\“阿玛\”我奥勒帕\“你。
■Uafaailoamaiilesuesuega,leta\'ateleolefa\'ama\'iolepo\'u(脓疱病)uamauaailefanauaoga(57%),我AoganaFaiaaileSuesuega.Osefainumerauamaualugateleilelalolagiatoa.etoateleatunisiolefanaulaiti(年轻)matama(男性)emauailepo\'unailoisitamaiti.Olefainumeraoleutuolepa'u(sc疮)(14·4%)etutusa熔岩maisimotuolePasefika。Olefeaveainaolesiamafaapitoa(金黄色葡萄球菌)uatupuleailefanauuaao\'ogaileaogaetasi.Eletoatelefoinisiolefanau(2%)namauailesiamafaapitoaolefa\ai(链球菌化脓)eonamafuaailefivarumatika.奥列伊·法努玛·阿塔图萨·马苏苏埃加·法萨尼西娜·法伊·穆阿马·萨摩亚。
■Oleaotelegalaoleneisuesuegafaasaenisi,uafaailoainamaiailetelenauaolefa\'ama\'iolepa\'u,opo\'u(脓疱病)maleutuolepa\'u(sc疮)i萨摩亚nei。Oneifoisuesuegaoleaaogateleinipolokalamemanifuafuagamamaoefafoisiaaineifaafitaulilesoifuamalloinaolefanaui萨摩亚.Oleaaveafoineifainumeraefaamamaumainamolesilafiaeleatunuumalesoifuamaloloina,Leta\'ateleoneifa\'amaiolepa\'u,莫勒·塔佩纳娜·尼福福·塔拉菲盖伊·泰米·伊·卢马,我是faaitiitinaailepipissioneisiamiifanau\'ogaiSamoa.
UNASSIGNED: Common infections of the skin such as impetigo and scabies represent a large burden of disease globally, being particularly prevalent in tropical and resource-limited settings. Efforts to address these infections through mass drug administrations have recently been shown as efficacious and safe. In Samoa, a Pacific Island nation, there is a marked lack of epidemiological data for these neglected tropical diseases, or appreciation of their drivers in this setting.
UNASSIGNED: An observational, cross-sectional survey of children aged between 4 and 15 years attending primary schools in rural areas of Upolu Island, Samoa was carried out to assess the prevalence of impetigo and scabies in schoolchildren residing in rural Samoa, integrated with descriptive epidemiological and microbial genomic data. A phylogenetic assessment of local Staphylococcus aureus isolated from Samoan schoolchildren was performed to estimate putative community transmission.
UNASSIGNED: In this survey, the prevalence of impetigo observed in Samoan schoolchildren was one of the highest described globally (57•1%, 95% CI [53•8-60•5%], 476/833). Associations between active impetigo and age and gender were noted, with younger children and males more commonly affected (aOR2•8 [1•8-4•7]and aOR1•8 [1•3-2•5], respectively). The prevalence of scabies was similar to that seen in other South Pacific island countries (14•4%, 95% CI [12•2-17•0%], 120/833). Transmission of S. aureus was predicted, primarily between those children attending the same school. Carriage of S. pyogenes was notably low, with pharyngeal carriage observed in less than 2% of schoolchildren, consistent with earlier studies from Samoa.
UNASSIGNED: This
study describes a considerable burden of disease attributed to impetigo and scabies in Samoa. These findings will be valuable in addressing the public health challenge posed by these conditions, providing baseline prevalence data and highlighting practical strategies to reduce transmission of relevant microbes and parasites in this setting.
UNASSIGNED: O a\'afiaga o le pa\'u i fa\'ama\'i o le po\'u (impetigo) ma le utu o le pa\'u (scabies), ua tele naua le fanau ua maua ai i le pasefika, ma le lalolagi atoa. O fuafuaga vaai mamao ma polokalame e fofoina ai nei faafitauli, e aofia ai le inumaga o fualaau e tapeina ai nei fa\'ama\'i, ua aliali mai ai e mafai ona faatamaia nei fa\'ama\'i. E le o tele ni tusitusiga ma faamaumauga i totonu o Samoa, pe ta\'atele nei fa\'amai o le pa\'u pe leai. Ona o le le faatauaina o nei fa\'ama\'i, e le o iloa fo\'i ni mafuaga ma nisi tulaga e faateleina ai nei fa\'ama\'i o le pa\'u i Samoa.
UNASSIGNED: O le suesuega faasaenisi i le fanau aoga i le va o le 4 ma le 15 tausaga o loo ao\'oga i le tulaga lua i nisi o nu\'u i tua i Upolu, na faatinoina ai suesuega lea, ia suesueina ai le aotelega ma fainumera o le fanau ua maua i fa\'ama\'I o le po\'u (impetigo) ma le utu o le pa\'u (scabies). O lenei foi suesuega, na fia iloa ai fo\'i po\'o a ituaiga siama eseese o loo maua i luga o pa\'u ma tino o le fanau aoga, ina ia iloa ai foi auala ua pipisi ai nei siama mai le isi tamaitiiti i le isi, ona mafua ai lea o nei fa\'ama\'i o le pa\'u.
UNASSIGNED: Ua faailoa mai i le suesuega, le ta\'atele o le fa\'ama\'i o le po\'u (impetigo) ua maua ai le fanau aoga (57%), i aoga na faia ai le suesuega. O se fainumera ua maualuga tele i le lalolagi atoa. E toatele atu nisi o le fanau laiti (younger) ma tama (male) e maua i le po\'u nai lo isi tamaiti. O le fainumera o le utu o le pa\'u (scabies) (14·4%) e tai tutusa lava ma isi motu o le Pasefika. O le feaveaina o le siama faapitoa (staph aureus) ua tupu lea i le fanau ua ao\'oga i le aoga e tasi. E le toatele foi nisi o le fanau (2%) na maua i le siama faapitoa o le fa\'ai (strep pyogenes) e ona mafua ai le fiva rumatika. O lenei fainumera ua tai tutusa ma suesuega faasaenisi na fai muamua i Samoa.
UNASSIGNED: O le aotelega la o lenei suesuega faasaenisi, ua faailoaina mai ai le tele naua o le fa\'ama\'i o le pa\'u, o po\'u (impetigo) ma le utu o le pa\'u (scabies) i Samoa nei. O nei foi suesuega o le a aoga tele ini polokalame ma ni fuafuaga mamao e fa\'afoisia ai nei faafitauli i le soifua maloloina o le fanau i Samoa. O le a avea foi nei fainumera e faamaumauina mo le silafia e le atunuu ma le soifua maloloina, le ta\'atele o nei fa\'amai o le pa\'u, mo le tapenaina o ni fofo talafeagai ise taimi o i luma, ina ia faaitiitina ai le pipisi o nei siami i fanau ao\'oga i Samoa.