myocardial viability

心肌活力
  • 文章类型: Journal Article
    这项研究旨在评估实施亚洲心血管成像学会实用教程2020(ASCI-PT2020)的共识声明对心脏MR晚期g增强(CMR-LGE)心肌活力评分的可靠性的影响在缺血性心肌病的背景下。
    共有来自五个不同国家的17名心血管成像专家评估了26名患者(男性:女性,23:3;中位年龄[四分位数范围],55.5年[50-61.8])伴有缺血性心肌病。对于LGE评分,根据17段,根据共识声明,使用暴露前后0~4分5分评分系统对各段的LGE程度进行评分.所有评分均通过基于网络的审查进行。切片的分数,维管区,总分作为相关节段得分的总和。使用Fleiss\'kappa评估段分数的观察者间可靠性,虽然组内相关系数(ICC)用于切片评分,血管区域评分,和总分。使用来自平均值(LoA)的协议限制来评估观察员之间的协议。
    在共识之前,每个部分的观察者间可靠性(Fleiss\'kappa)范围为0.242-0.662,在共识之后增加到0.301-0.774。每个切片的观察者间可靠性(ICC),每个血管区域,共识后总分增加(切片,0.728-0.805和0.849-0.884;血管区域,0.756-0.902和0.852-0.941;总分,0.847和0.913,在执行共识声明之前和之后,分别。随着所有切片的共识的实施,观察员之间在评分方面的共识也得到了改善,维管区,和总分。总分的LoA从±10.36分缩小到±7.12分。
    遵循ASCI-PT2020共识声明的指导,缺血性心肌病CMR-LGE评分的观察者间可靠性和一致性得到改善。
    This study aimed to evaluate the effect of implementing the consensus statement from the Asian Society of Cardiovascular Imaging-Practical Tutorial 2020 (ASCI-PT 2020) on the reliability of cardiac MR with late gadolinium enhancement (CMR-LGE) myocardial viability scoring between observers in the context of ischemic cardiomyopathy.
    A total of 17 cardiovascular imaging experts from five different countries evaluated CMR obtained in 26 patients (male:female, 23:3; median age [interquartile range], 55.5 years [50-61.8]) with ischemic cardiomyopathy. For LGE scoring, based on the 17 segments, the extent of LGE in each segment was graded using a five-point scoring system ranging from 0 to 4 before and after exposure according to the consensus statement. All scoring was performed via web-based review. Scores for slices, vascular territories, and total scores were obtained as the sum of the relevant segmental scores. Interobserver reliability for segment scores was assessed using Fleiss\' kappa, while the intraclass correlation coefficient (ICC) was used for slice score, vascular territory score, and total score. Inter-observer agreement was assessed using the limits of agreement from the mean (LoA).
    Interobserver reliability (Fleiss\' kappa) in each segment ranged 0.242-0.662 before the consensus and increased to 0.301-0.774 after the consensus. The interobserver reliability (ICC) for each slice, each vascular territory, and total score increased after the consensus (slice, 0.728-0.805 and 0.849-0.884; vascular territory, 0.756-0.902 and 0.852-0.941; total score, 0.847 and 0.913, before and after implementing the consensus statement, respectively. Interobserver agreement in scoring also improved with the implementation of the consensus for all slices, vascular territories, and total score. The LoA for the total score narrowed from ± 10.36 points to ± 7.12 points.
    The interobserver reliability and agreement for CMR-LGE scoring for ischemic cardiomyopathy improved when following guidance from the ASCI-PT 2020 consensus statement.
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  • 文章类型: Journal Article
    在临床决策中,心肌活力定义为急性或慢性冠状动脉疾病和其他有收缩功能障碍但保持代谢和电功能的情况下的心肌。有可能改善血管重建术或其他治疗后的功能障碍。几种病理生理条件可以共存来解释这种现象。心脏成像可以通过不同的原理识别心肌的活力,目的是预测治疗反应和选择治疗方法。这份专家共识文件回顾了对潜在病理生理学和评估生存能力的可用方法的最新见解。特别是该文件回顾了当代生存能力成像技术,包括应力超声心动图,单光子发射计算机断层扫描,正电子发射断层扫描,心血管磁共振,和计算机断层扫描,并就如何在采集和解释方面标准化这些方法提供临床建议。最后,它提出了临床方案,其中生存能力评估在临床上有用。
    In clinical decision making, myocardial viability is defined as myocardium in acute or chronic coronary artery disease and other conditions with contractile dysfunction but maintained metabolic and electrical function, having the potential to improve dysfunction upon revascularization or other therapy. Several pathophysiological conditions may coexist to explain this phenomenon. Cardiac imaging may allow identification of myocardial viability through different principles, with the purpose of prediction of therapeutic response and selection for treatment. This expert consensus document reviews current insight into the underlying pathophysiology and available methods for assessing viability. In particular the document reviews contemporary viability imaging techniques, including stress echocardiography, single photon emission computed tomography, positron emission tomography, cardiovascular magnetic resonance, and computed tomography and provides clinical recommendations for how to standardize these methods in terms of acquisition and interpretation. Finally, it presents clinical scenarios where viability assessment is clinically useful.
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