■感染性心内膜炎是一种具有挑战性的诊断,通常需要心血管影像确认作为方法的一部分。18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(18F-FDG-PET/CT)是一种成像技术,在超声心动图不确定的情况下,对诊断人工瓣膜心内膜炎(PVE)更敏感。
我们介绍了一个35岁男子的案例,该男子在4年前曾进行过Bentall-DeBono手术,其中包括生物学,国家心脏病研究所(INC)类型,本地制造的主动脉瓣置换术和在升主动脉中的编织涤纶管移植物植入。他因呼吸困难入院,水肿,发烧,和晕厥。诊断为完全性耳室阻滞,需要心脏起搏.此外,怀疑感染性心内膜炎(IE).血液培养显示地衣芽孢杆菌的分离。经胸超声心动图,经食管超声心动图,和CT血管造影对IE尚无定论。开始静脉(IV)抗生素治疗,和一个广泛的IE协议,包括分子成像模式,被命令了。获得99mTc-Ubiquicidin闪烁显像没有异常发现。18F-FDG-PET/CT图像显示人工主动脉瓣环以经典模式异常强烈的异质摄取。适用于PET/CT的修改后的2015年Duke标准,PVE已确认。
■尽管其他成像方式均为阴性,高度的临床怀疑使得必须继续研究方案,关于18F-FDG-PET/CT对被归类为“可能”心内膜炎的患者的实用性,就像我们的病人一样。
UNASSIGNED: Infective endocarditis is a challenging diagnosis that usually requires cardiovascular image confirmation as part of the approach. 18F-Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) is an imaging technique more sensible for the diagnosis of prosthetic valve endocarditis (PVE) when echocardiography is inconclusive.
UNASSIGNED: We present the
case of a 35-year-old man who had a previous Bentall-De Bono procedure 4 years prior that included biological, national institute of cardiology (INC)-type, locally manufactured aortic valve replacement and woven Dacron tube graft implantation in the ascending aorta. He was admitted because of dyspnoea, oedema, fever, and syncope. A complete auriculoventricular blockade was diagnosed, requiring cardiac pacing. Also, infective endocarditis (IE) was suspected. Blood cultures showed the isolation of Bacillus licheniformis. Transthoracic echocardiography, transoesophageal echocardiography, and CT angiography were inconclusive for IE. Treatment was initiated with intravenous (IV) antibiotic therapy, and an extensive protocol for IE, including molecular imaging modalities, was ordered. 99mTc-Ubiquicidin scintigraphy was acquired without abnormal findings. Images of 18F-FDG-PET/CT revealed abnormally intense heterogeneous uptake in the prosthetic aortic annulus in a classic pattern. Applying the modified 2015 Duke criteria for PET/CT, PVE was confirmed.
UNASSIGNED: Although the other imaging modalities were negative, the high clinical suspicion made it mandatory to continue the study protocol, remarking on the utility of 18F-FDG-PET/CT on patients categorized as having \'possible\' endocarditis, as in our patient.