在硬腭出现任何病变的情况下,排除它们可能的牙源性起源总是很重要的。锥形束计算机断层扫描是强制性的。如果证实了可能的非牙齿相关病理,每位临床医生都应记住可能的鉴别诊断.在粘膜和骨之间的许多小唾液腺存在于这个腭区域。由小腺体引起的良性和恶性肿瘤,和硬腭的粘膜,可能发生。由于结节的一致性,此处介绍的病例模仿了实体瘤。由于健康的腭粘膜没有任何侵蚀或刺激,与粘膜下结节牢固连接,在这种情况下,怀疑可能是小唾液腺起源的恶性肿瘤。当肿瘤直径较小时,需要进行切除活检以收集良好且具有代表性的材料,以进行进一步的组织病理学评估。在大多数情况下,在触诊时,腭上存在的大结节很难,不可移动,覆盖着健康的粘膜.粘膜溃疡可能的骨浸润可能表现出病变的扩张性。在本案中,首次与腺样囊性癌(ACC)的发生区分开来,发生了不寻常的创伤性神经瘤,没有任何过去的创伤性病因,多形性腺瘤,其他良性/恶性小腺体肿瘤,或非典型的,腭纤维瘤/神经鞘瘤。本文介绍了42岁男性患者中这种罕见的口腔神经肿瘤的治疗选择以及硬腭肿瘤之间的鉴别诊断。进一步强调了切除活检作为组织样本的良好来源的作用。
In the
case of any pathologies arising in the hard palate, it is always important to exclude their possible odontogenic origins. Cone-beam computed tomography is mandatory. In cases where a possible non-teeth-related pathology is confirmed, each clinician should remember possible differential diagnostics. Many small salivary glands between the mucosa and bone are present in this palatal area. Both benign and malignant tumors arising from the small glands, and mucosa of the hard palate, might occur. The
case presented here mimics a solid tumor because of the nodule consistency. Because of a healthy palatal mucosa without any erosions or irritations with firm attachment to the submucosal nodule, a possible malignant tumor of small salivary gland origins was suspected in this
case. When the tumor diameter is small, an excisional biopsy is required to collect good and representative material for further histopathological evaluation. In most cases, bulky nodules present on the palate are hard on palpation, non-movable, and covered with healthy mucosa. Possible bone infiltrations with mucous membrane ulcerations could manifest a more expansive character of the lesion. In the presented
case, an unusual occurrence of a traumatic neuroma without any past traumatic etiology of the palate was first differentiated from the occurrence of adenoid-cystic carcinoma (ACC), pleomorphic adenoma, other benign/malignant small gland tumors, or atypical, fibroma/schwannoma of the palate. This paper presents treatment options for this rare oral neural tumor occurrence in the palate and differential diagnosis between hard palate tumors in a 42-year-old male patient, furthermore highlighting the role of an excisional biopsy as a good source for a tissue sample.