滑膜肉瘤(SSs)是一组罕见的起源于多能间充质细胞的恶性肿瘤,通常发生在关节面附近软组织的原发性肿瘤,肌腱,和关节滑膜.在这里,我们报告了一例罕见的纵隔SS病例,该病例发生在一名18岁青少年中,最初以咳嗽为主要症状.在这种情况下,胸部平扫CT和对比增强CT清楚地显示,纵隔中的病变表现为圆形和不均匀的密度肿块,并伴有不均匀的增强,压缩气管并侵入相邻的血管。根据免疫组织化学和荧光原位杂交(FISH)的结果,结合影像学与纵隔其他类型肿瘤的鉴别诊断,我们能够将肿瘤诊断为位于纵隔的SS.随后切除病灶,再加上化疗和免疫治疗可改善患者的症状。
Synovial sarcomas (SSs) are a rare group of malignant tumors originating from pluripotential mesenchymal cells, which commonly occur as the primary tumor in the soft tissues near the articular surface, tendons, and articular synovium. Herein, we report a rare
case of mediastinal SS in an 18-year-old teenager who initially presented with cough as the primary symptom. In this
case, plain chest CT and contrast-enhanced CT clearly revealed the lesion presenting as a round-like and uneven density mass in the mediastinum with heterogeneous enhancement, which compressed the trachea and invaded the adjacent vessels. Based on the results of immunohistochemistry and fluorescence in situ hybridization (FISH), combined with the differential diagnosis with other types of tumors in the mediastinum on imaging, we were able to diagnose the tumor as an SS located in the mediastinum. Subsequent resection of the lesion coupled with chemotherapy and immunotherapy led to an improvement in the patient\'s symptoms.