mental disease

  • 文章类型: Systematic Review
    这项研究在精神卫生保健创新设计研究中检查并反映了具有精神病症状和特征的人作为目标人群的频率。
    This study examined and reflected on the frequency of people with psychotic symptoms and features as the target population in design studies for mental health care innovation.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    西方饮食是一种现代饮食模式,其特征是大量摄入预先包装的食物,精制谷物,红肉,加工肉,高糖饮料,糖果,糖果,油炸食品,传统饲养的动物产品,高脂肪乳制品,和高果糖产品。本综述旨在描述西方模式饮食对新陈代谢的影响,炎症,和抗氧化状态;对肠道微生物群和线粒体适应性的影响;对心血管健康的影响,心理健康,和癌症;以及西方饮食的卫生成本。为了实现这一目标,使用主要来源进行了共识性批判性审查,比如科学文章,和次要来源,包括书目索引,数据库,和网页。Scopus,Embase,科学直接,体育讨论,ResearchGate,和WebofScience被用来完成任务。符合MeSH的关键词,如“西方饮食”,\"炎症\",“代谢健康”,“代谢适应性”,“心脏病”,\"癌症\",“氧化应激”,“心理健康”,和“新陈代谢”被使用。适用以下排除标准:(i)主题不适当或无关的研究,与审查的主要重点没有密切关系;(二)博士学位论文,会议记录,和未发表的研究。这些信息将有助于更好地理解这种营养行为及其对个体新陈代谢和健康的影响,以及对国家卫生系统的影响。最后,从这些信息中得出的实际应用。
    The Western diet is a modern dietary pattern characterized by high intakes of pre-packaged foods, refined grains, red meat, processed meat, high-sugar drinks, candy, sweets, fried foods, conventionally raised animal products, high-fat dairy products, and high-fructose products. The present review aims to describe the effect of the Western pattern diet on the metabolism, inflammation, and antioxidant status; the impact on gut microbiota and mitochondrial fitness; the effect of on cardiovascular health, mental health, and cancer; and the sanitary cost of the Western diet. To achieve this goal, a consensus critical review was conducted using primary sources, such as scientific articles, and secondary sources, including bibliographic indexes, databases, and web pages. Scopus, Embase, Science Direct, Sports Discuss, ResearchGate, and the Web of Science were used to complete the assignment. MeSH-compliant keywords such \"Western diet\", \"inflammation\", \"metabolic health\", \"metabolic fitness\", \"heart disease\", \"cancer\", \"oxidative stress\", \"mental health\", and \"metabolism\" were used. The following exclusion criteria were applied: (i) studies with inappropriate or irrelevant topics, not germane to the review\'s primary focus; (ii) Ph.D. dissertations, proceedings of conferences, and unpublished studies. This information will allow for a better comprehension of this nutritional behavior and its effect on an individual\'s metabolism and health, as well as the impact on national sanitary systems. Finally, practical applications derived from this information are made.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    Alzheimer\'s disease (AD) and vascular dementia (VaD) are major types of dementia, both of which cause heavy economic burdens for families and society. However, no currently available medicines can control dementia progression. Rhizoma coptidis, a Chinese herbal medicine, has been used for >2000 years and is now gaining attention as a potential treatment for AD and VaD.
    We reviewed the mechanisms of the active ingredients of Rhizoma coptidis and Rhizoma coptidis-containing Chinese herbal compounds in the treatment of AD and VaD. We focused on studies on ameliorating the risk factors and the pathological changes of these diseases.
    The Rhizoma coptidis active ingredients include berberine, palmatine, coptisine, epiberberine, jatrorrhizine and protopine. The most widely studied ingredient is berberine, which has extensive therapeutic effects on the risk factors and pathogenesis of dementia. It can control blood glucose and lipid levels, regulate blood pressure, ameliorate atherosclerosis, inhibit cholinesterase activity, Aβ generation, and tau hyperphosphorylation, decrease neuroinflammation and oxidative stress and alleviate cognitive impairment. Other ingredients (such as jatrorrhizine, coptisine, epiberberine and palmatine) also regulate blood lipids and blood pressure; however, there are relatively few studies on them. Rhizoma coptidis-containing Chinese herbal compounds like Huanglian-Jie-Du-Tang, Huanglian Wendan Decoction, Banxia Xiexin Decoction and Huannao Yicong Formula have anti-inflammatory and antioxidant stress activities, regulate insulin signaling, inhibit γ-secretase activity, neuronal apoptosis, tau hyperphosphorylation, and Aβ deposition, and promote neural stem cell differentiation, thereby improving cognitive function.
    The \"One-Molecule, One-Target\" paradigm has suffered heavy setbacks, but a \"multitarget- directed ligands\" strategy may be viable. Rhizoma coptidis active ingredients and Rhizoma coptidiscontaining Chinese herbal compounds have multi-aspect therapeutic effects on AD and VaD.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • DOI:
    文章类型: Journal Article
    暂无摘要。
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

公众号