■全血细胞减少症是贫血的一种分类,白细胞减少症,和血小板减少症.导致全血细胞减少的病因因年龄等因素而异,性别,职业,和地理分布。不幸的是,血液学的主要论文没有强调引起全血细胞减少症的不同病因的出血表现。
■这项观察性研究旨在确定印度东部全血细胞减少症患者的出血表现。
■这项研究是在印度东部一家三级护理教学机构的医学系进行的,为期两年。所有有贫血特征的患者,血小板减少症,对全血细胞减少症或白细胞减少症进行筛查,共选择214例。患者分为两组,年龄大于14岁的患者构成第一组,小于14岁的患者构成第二组。详细的体检,血液学,并进行生化检查以确定全血细胞减少症患者的出血表现。
■在组中,全血细胞减少症患者出血表现的最常见原因是再生障碍性贫血,白血病,骨髓增生异常综合征,和骨髓纤维化。巨幼细胞性贫血患者未见出血表现,kala-azar,脾功能亢进,以及其他导致全血细胞减少的原因。
■由再生障碍性贫血引起的全血细胞减少症患者,急性白血病,与巨幼细胞性贫血引起的全血细胞减少相比,骨髓增生异常综合征有更多的出血机会,kala-azar,或者脾功能亢进.
UNASSIGNED: Pancytopenia is a triage of anemia, leukopenia, and thrombocytopenia. The etiology causing pancytopenia varies depending upon factors such as age, sex, occupation, and geographical distribution. Unfortunately, the major treatises of hematology have not given emphasis on the hemorrhagic manifestation of different etiologies causing pancytopenia.
UNASSIGNED: This observational
study was carried out with the aim to identify hemorrhagic manifestation in patients with pancytopenia in eastern India.
UNASSIGNED: This
study was conducted over a period of two years at the Department of Medicine of a tertiary care teaching institute in eastern India. All the patients with features of anemia, thrombocytopenia, or leukopenia were screened for pancytopenia and a total of 214 cases were selected. Patients were divided into two groups as patients with age more than 14 years constitute group one and the patients less than 14 years constitute the second group. A detailed physical examination, hematological, and biochemical investigation was done to ascertain the hemorrhagic manifestations in pancytopenia patients.
UNASSIGNED: In the groups, the most common cause of hemorrhagic manifestation in patients with pancytopenia was aplastic anemic, leukemia, myelodysplastic syndrome, and myelofibrosis. No bleeding manifestation was seen in patients with megaloblastic anemia, kala-azar, hypersplenism, and other causes of pancytopenia.
UNASSIGNED: Patients with pancytopenia caused by aplastic anemia, acute leukemia, and myelodysplastic syndrome have more chances of bleeding manifestation as compared with pancytopenia caused by megaloblastic anemia, kala-azar, or hypersplenism.