自1970年代以来,甲褶毛细管镜检查(NFC)在诊断风湿病如系统性硬化症中的应用已经得到了很好的证实.进一步的研究还表明,NFC可以检测非风湿性疾病,如糖尿病,青光眼,皮炎,和阿尔茨海默病。在过去的十年里,甲皱毛细血管形态变化也被报道为不健康的生活习惯的症状,如不良的饮食习惯,吸烟,睡眠剥夺,甚至心理压力,所有这些都会导致血液流动缓慢。因此,研究甲皱毛细血管的形态与生活习惯之间的关系很有可能表明不健康的状态,甚至是疾病前的状况。简单,便宜,和诸如NFC的非侵入性方法对于常规医学检查是重要且有用的。本研究从PubMed数据库的系统文献检索开始,然后是报告通过NFC检测到的形态学变化的评估的研究摘要。并全面审查NFC在临床诊断和改善不健康饮食生活方式中的效用。它总结了饮食和生活方式健康促进策略,基于NFC和其他指示健康微血管血流和内皮功能的相关测量进行评估。
Since the 1970s, the utility of nailfold capillaroscopy (NFC) in diagnosing rheumatological disorders such as systemic sclerosis has been well established. Further studies have also shown that NFC can detect non-rheumatic diseases such as diabetes, glaucoma, dermatitis, and Alzheimer disease. In the past decade, nailfold capillary morphological changes have also been reported as symptoms of unhealthy lifestyle habits such as poor diet, smoking, sleep deprivation, and even psychological stress, all of which contribute to slow blood flow. Therefore, studying the relationships between the morphology of nailfold capillaries and lifestyle habits has a high potential to indicate unhealthy states or even pre-disease conditions. Simple, inexpensive, and non-invasive methods such as NFC are important and useful for routine medical examinations. The present study began with a systematic literature search of the PubMed database followed by a summary of studies reporting the assessment of morphological changes detected by NFC, and a comprehensive
review of NFC\'s utility in clinical diagnosis and improving unhealthy dietary lifestyles. It culminates in a summary of dietary and lifestyle health promotion strategy, assessed based on NFC and other related measurements that indicate healthy microvascular blood flow and endothelial function.