背景:术语先天性膈膨出(CDE)是指膈的解剖学异常。这是非常罕见的情况;然而,早期和及时诊断是非常重要的,因为可能危及生命的并发症。受影响最严重的病人是新生儿,通常表现为呼吸窘迫症状。本研究的目的是系统回顾现有文献,巩固新生儿CDE的数据,并报告一例先天性左半膈肌diaphragm肌膨出的新生儿以及胃肠道的临床体征和症状。
方法:对PubMed和Scopus数据库进行了电子搜索,涉及评估临床表现的研究,诊断方法,治疗,和新生儿人群CDE的结果。
结果:93项研究的数据被纳入我们的综述,报告204例CDE病例,根据他们的说法,男性/女性比例为1/1,主要为右侧外移。诊断主要通过胸部X光检查确定;手术干预是最常见的治疗方法。复发率为8.3%(9/109例)。
结论:早期准确的CDE诊断和膈肌修复可预防并发症,降低发病率,提高患者的生活质量。
BACKGROUND: The term congenital diaphragmatic eventration (CDE) refers to an anatomical abnormality of the diaphragm. It is a very rare condition; however, early and prompt diagnosis is of very great importance due to possible life-threatening complications. Most severely affected patients are neonates, usually presented with respiratory distress symptoms. The aim of this study was to systematically
review the existing literature and to consolidate data on CDE in neonates as well as to report a case of a neonate with congenital diaphragmatic eventration of the left hemidiaphragm and clinical signs and symptoms of the gastrointestinal tract.
METHODS: An electronic search of the PubMed and Scopus databases was performed regarding studies evaluating the clinical presentation, diagnosis methods, treatments, and outcomes of CDE in the neonatal population.
RESULTS: Data from 93 studies were integrated into our
review, reporting 204 CDE cases, and according to them, the male/female ratio was 1/1 with a predominance of right-sided eventration. The diagnosis was primarily established by chest X-ray; surgical intervention was the most frequent treatment. The recurrence rate was 8.3% (9/109 cases).
CONCLUSIONS: Early and accurate diagnosis of CDE and repair of the diaphragm can prevent complications, reduce morbidity, and improve the quality of patient\'s life.