女性生殖系统恶性肿瘤是一个严重的健康和社会问题,因为它们是女性死亡的第二大原因,乳腺癌后。外阴肿瘤仅占所有妇科肿瘤的4%,它们的频率仅次于子宫颈肿瘤,子宫,和卵巢。所有外阴肿瘤的98%是良性的,只有2%是恶性的。外阴肉瘤占所有外阴癌的约1-3%。他们的特点是快速增长,高转移潜能,频繁复发,攻击性行为,和高死亡率。在本文的第一部分中,我们介绍了最常见的外阴肉瘤形式:平滑肌肉瘤,上皮样肉瘤,恶性横纹肌样瘤,和横纹肌肉瘤.本综述的第二部分将主要集中在外阴肉瘤的最罕见的变种:低级别纤维粘液样肉瘤,滑膜肉瘤,单相滑膜肉瘤,癌肉瘤,尤因肉瘤,骨髓肉瘤,隆突性皮肤纤维肉瘤,恶性纤维组织细胞瘤,血管瘤样纤维组织细胞瘤,脂肪肉瘤,恶性周围神经鞘瘤,和恶性间皮瘤.
Malignant tumors of the female reproductive system are a serious health and social problem, as they are the second most common cause of death among women, after breast cancer. Vulvar tumors represent only 4% of all gynecological neoplasms, and they are fourth in frequency after tumors of the cervix, uterus, and ovary. Ninety-eight percent of all vulvar tumors are benign and only 2% are malignant. Sarcomas of the vulva comprise approximately 1-3% of all vulvar cancers. They are characterized by rapid growth, high metastatic potential, frequent recurrences, aggressive behavior, and high mortality rate. In Part 1 of this paper, we presented the most common forms of sarcoma of the vulva: leiomyosarcoma, epithelioid sarcoma, malignant rhabdoid tumor, and rhabdomyosarcoma. The second part of this review will focus mainly on the rarest variants of vulvar sarcoma: low-grade fibromyxoid sarcoma, synovial sarcoma, monophasic synovial sarcoma, carcinosarcoma, Ewing sarcoma, myeloid sarcoma, dermatofibrosarcoma protuberans, malignant fibrous histiocytoma, angiomatoid fibrous histiocytoma,
liposarcoma, malignant peripheral nerve sheath tumor, and malignant mesothelioma.