Abstract：
Preoperative biopsy for retroperitoneal sarcoma (RPS) enables appropriate multidisciplinary treatment planning. A systematic review of literature from 1990 to June 2022 was conducted using the population, intervention, comparison and outcome model to evaluate the local recurrence and overall survival of preoperative biopsy compared to those that had not. Of 3192 studies screened, five retrospective cohort studies were identified. Three reported on biopsy needle tract seeding, with only one study reporting biopsy site recurrence of 2 %. Two found no significant difference in local recurrence and one found higher 5-year local recurrence rates in those who had not been biopsied. Three studies reported overall survival, including one with propensity matching, did not show a difference in overall survival. In conclusion, preoperative core needle biopsy of RPS is not associated with increased local recurrence or adverse survival outcomes.
摘要：
腹膜后肉瘤（RPS）的术前活检可实现适当的多学科治疗计划。对1990年至2022年6月的文献进行了系统回顾，使用人口，干预，比较和结局模型，以评估术前活检与未活检的局部复发和总生存期。在筛选的3192项研究中，纳入5项回顾性队列研究.三次报告活检针道播种，只有一项研究报告活检部位复发2%。两个发现局部复发没有显着差异，一个发现在没有进行活检的人中5年局部复发率更高。三项研究报告了总生存率，包括一个倾向匹配的，没有显示总生存期的差异。总之,RPS术前芯针活检与局部复发或不良生存结局无关.
