背景:我们进行了一项范围审查,以分析过去十年中维生素D缺乏对女性生殖健康的影响和意义。考虑到温带行星带和气候变化的影响。
方法:我们使用了一种定性方法来对PubMed进行全景数据库审查,WebofScience,Scopus涵盖了过去十年的文章,重点是生活在高于40°N和40°S的纬度上的人群。我们用了气候变化,胆钙化醇或维生素d3,怀孕,和女人健康和布尔运算符AND和OR。我们排除了给编辑的信,reviews,协议,和没有人类参与者的临床试验,以及重复的文章。
结果:我们纳入了35项英文研究,其中大部分来自北美或欧洲。没有发现南半球或与气候变化有任何直接关系的研究,尽管研究表明纬度和环境因素影响维生素D缺乏,这对孕妇和他们的孩子产生了影响。补充准则没有很好地制定,并且在高危女性群体中缺乏研究(例如,深色皮肤,高纬度地区,移民)贯穿一生。
结论:维生素D缺乏是影响女性生殖健康的全球性环境问题,取决于多种环境因素和人类行为。因此,我们建议在公共政策和临床研究中考虑环境和社会文化因素,并更多地研究补充和强化策略的有效性。从事生殖健康工作的卫生保健专业人员需要采取行动来检测,教育,以及预防妇女一生中维生素D缺乏,考虑到这种现象的多重性,其中包括人口健康中的环境和气候因素。
We conducted a scoping
review to analyze the effects and implications of vitamin D deficiency on female reproductive health during the last decade, considering temperate planetary zones and climate change impacts.
We used a qualitative methodology for a panoramic database
review of PubMed, Web of Science, and Scopus covering articles from the last decade focused on populations living at latitudes higher than 40° N and 40° S. As descriptors, we used the phrases climate change, cholecalciferol or vitamin d3, pregnancy, and woman health and the Boolean operators AND and OR. We excluded letters to the editor, reviews, protocols, and clinical trials without human participants, as well as duplicate articles.
We included 35 studies in English, the majority of which were from North America or Europe. No studies were found from the Southern Hemisphere or having any direct relation with climate change, although studies demonstrated that
latitude and environmental factors affected vitamin D deficiency, which had an impact on pregnant women and their children. Supplementation guidelines were not well developed, and there was a lack of studies among at-risk groups of women (eg, darker skin, higher latitudes, immigrants) across the life span.
Vitamin D deficiency is a global environmental problem that affects female reproductive health and depends on multiple environmental factors and human behavior. Therefore, we recommend consideration of environmental and sociocultural factors in public policy and clinical research and more research on the effectiveness of supplementation and fortification strategies. Health care professionals working in reproductive health need to generate actions for detection of, education on, and prevention of vitamin D deficiency among women across their life spans, considering the multicausality of the phenomenon, which includes environmental and climate factors in population health.